符雲新

符雲新 Yun-xin Fu
符雲新(Yun-xin Fu)教授，海南東方人，美國德克薩斯州立大學人類遺傳學研究中心（ UT-Houston School of Public Health Human Genetics Center）特聘教授，雲南大學特聘教授，《genetics》雜誌副主編。
符教授在群體遺傳學和理論進化遺傳學界有很高聲望。他提出的幾種符氏理論在中性檢驗中有廣泛套用，是群體遺傳教科書中必不可少的內容。美國NIH遺傳研究委員會成員，世界著名雜誌《遺傳學》（Genetics）和《分子生物學和進化》（Molcular Biology and evolution）副主編。
1982年畢業於中山大學；1986-1988年在英國雷丁大學從事生物統計學研究，獲博士學位；1988-1989年、1989-1990年、1990-1991年分別在英國國家醫學研究院、美國喬治亞大學、德克薩斯大學從事博士後研究。主要從事計算生物學研究, 包括分子群體遺傳學和分子進化；自2003年起擔任雲南省生物資源保護與利用重點實驗室特聘教授，組建了計算基因組學實驗室並任研究組長，目前已招收數名博士和碩士研究生。

Research Interests: Molecular evolution; population genetics; bioinformatics; computational
genomics The long term objective of my research is to characterize the molecular evolution of
organism and to reconstruct the evolutionary histories of genes and species. Approaches
include (1) mathematical development of the theories of population genetics and evolution of
DNA sequences; (2) development of statistical methods for analyzing molecular data and for
reconstructing molecular phylogenies, especially the methods for testing important hypotheses
about molecular evolution; and (3) utilization of databases of the human genome as well as
other organisms for comparative study, including functional analysis of DNA polymorphism.
A tutorial in my laboratory would provide experiences in the mathematics and statistics of
population genetics, molecular evolution, molecular data analysis and programming in Java.
Publications:
Fu YX (2001) Estimating mutation rate and generation time from longitudinal samples of DNA sequences. Molecular Biology & Evolution. 18:620-626
Fu YX, Li WH (1999) Coalescing into the 21st century: An overview and prospects of coalescent theory. Theoretical Population Biology 56:1-10
Fu YX, Chakraborty R(1998) Simultaneous estimation of all the parameters of a stepwise mutation model. Genetics. 150:487-497
Deng HW, Fu YX (1998) On the three methods for estimating deleterious genomic mutation parameters. Genetical Res. 71:223-236
Fu YX(1998) Probability of a segregating pattern in a sample of DNA sequences. Theoret Popul Biol 54:1-10
Deng HW, Fu YX (1998) Conditions for positive and negative correlations between fitness and heterozygosity in equilibrium populations. Genetics. 148:1333-40
Fu YX (1997) Statistical tests of neutrality of mutations against population growth, hitchhiking and background selection. Genetics. 147:915-25
Fu YX (1997) Coalescent theory for a partially selfing population. Genetics. 146:1489-99
Deng HW, Fu YX (1996) The effects of variable mutation rates across sites on the phylogenetic estimation of effective population size or mutation rate of DNA sequences. Genetics. 144:1271-81
Fu YX (1996) Estimating the age of the common ancestor of a DNA sample using the number of segregating sites. Genetics. 144:829-38