黃小芹:黃小芹（曾用名黃明敏），湖南常德人，1980年生。現任湖南大學生 -百科知識中文網

個人簡介

2008年至今畢在湖南大學生物院工作。主講過的課程有《普通生物學》、《生物化學》、《生物化學實驗》等專業課程及實驗課程。在《JBiolChem》等知名學術刊物上共發表學術論文10餘篇。獲“湖南師範大學優秀畢業生”獎、第六屆亞洲白內障學術年會優秀報告獎。作為主要人員參加國家級、部省級科研課題多項。現階段主要從事的研究內容為轉錄因子對幹細胞多能性維持和定向分化的作用。

研究成果

[1]HuangX-Q,WangJ,LiuJ-P,FengH,YanQ,LiuW-B,LiuY,SunS-M,DengM,GongL,YunLiuandLi,D.W-C.hTERTextendsproliferativelifespanandpreventsreplicativesenescenceandoxidativestress-inducedapoptosisinhumanlensepithelialcells.Invest.Ophthalmol.Vis.Sci.2005,46,5203-5213.
[2]WangJ,FengH,HuangX-Q(Co-FirstAuthors),XiangH,Y-W.Mao,LiuJ-P,YanQ,LiuW-B,LiuY,DengM,GongL,SunS-M,YunLiuandLi,D.W-C.(2005).hTERTimmortalizesbovinelensepithelialcellsandsuppressesdifferentiationthroughregulationoftheERKsignalingpathway.J.Biol.Chem.280,22776-22787.
[3]ZhongqiuXie,GuixiangTan,MiaoDing,DifeiDong,TuanhuiChen,XiangxianMeng,XiaoqinHuangandYongjunTan.Foxm1transcriptionfactorisrequiredformaintenanceofpluripotencyofP19embryonalcarcinomacells.NucleicAcidsResearch.2010.
[4]Y.Tan,Y.Chen,L.Yu,H.Zhu,X.Meng,X.Huang,L.Meng,M.Ding,Z.WangandL.Shan.Two-foldelevationofexpressionofFoxM1transcriptionfactorinmouseembryonicfibroblastsenhancescellcyclecheckpointactivitybystimulatingp21andChk1transcription.CellProlif.2010.
[5]QinYan,LiliGong,MiDeng,LanZhang,ShumingSun,JiaoLiu,HailiMa,DanYuan,Pei-ChaoChen,XiaohuiHu,Jin-PingLiu,JichaoQin,LingXiao,XiaoqinHuang,JianZhang,DavidLi.SUMOylationActivatestheTranscriptionalActivityofp32Pax-6,AnImportantTranscriptionFactorforEyeandBrainDevelopment.PNAS,2010.
[6]YongjunTan,ZhongqiuXie,MiaoDing,ZhendongWang,QiqiYu,LeiMeng,HongZhu,XiaoqinHuang,LiYu,XiangxianMeng,andYanChen.IncreasedLevelsofFoxA1TranscriptionFactorinPluripotentP19EmbryonalCarcinomaCellsStimulateNeuralDifferentiation.StemCellsandDevelopment.2009.
[7]QinYan,Wen-BinLiu,JichaoQin,JingpingLiu,He-GeChen,HuangX-Q,LiliChen,ShumingSun,MDeng,MiDeng,LiliGong,YongLi,LanZhang,YanLiu,HaoFeng,YameiXiao,YunLiuandDavidW-CLi.ProteinPhosphatase-1dephosphorylatesPax-6,atranscriptionfactorcontrollingbrainandeyedevelopment.J.Biol.Chem.2007.282(9):13954–13965
[8]HaoFeng,HuaXiang,Ying-WeiMao,JuanWang,Jin-PingLiu,HuangX-Q,YanLiu,Shao-JunLiu,ChenLuo,Xuan-JieZhang,YunLiuandDavidWan-ChengLi.HumanBcl-2activatesERKsignalingpathwaytoregulateactivatingprotein-1,lensepithelium-derivedgrowthfactoranddownstreamgenes.Oncogene(2004)23,7310–7321.
[9]HuangX-Q,LiuY,DengM,GongL,SunS-M,ZhangL,ChenLL,FengH,LiuYandDavidW-CLi.TheERKMAPKinasesregulateeyedevelopmentingoldfish.The6thAsiancataractResearchConference，2006,30.
[10]HuangX-Q,LiuY,FengH,LiuW-B,YanQ,LuoC,LiuS-J,ZhangX-J,LiuYandD.W.Li.MapKinasesRegulateEye.ARVOProgramSummaryBook，2005,153.
[11]黃明敏,陳金輝,鄭康,羅琛.草魚基因組隨機擴增多態性引物及多態性位點的篩選.中國科學與工程，2004，4(2):91-96.
[12]陳金輝,黃明敏,鄭康,羅琛.兩個不同的人工雌核發育草魚群體基因組DNA的RAPD分析.水生生物學報,2004,28(5):471-477.
[13]劉正華,陳金輝,黃明敏，鄭康，羅琛.草魚基因組DNA一些RAPD位點的遺傳分析及分子標記篩選.水生生物學報，2006,30（3）:292-297.