簡介
正向遺傳學(forward genetics)
A classical genetic approach, where one starts with a mutation phenotype and works toward identifing the mutated gene.
相關
研究突變表型以確定突變基因的傳統遺傳學方法。
One of the first tools available to molecular geneticists is the forward genetic screen. The aim of this technique is to identify mutations that produce a certain phenotype. A mutagen is very often used to accelerate this process. Once mutants have been isolated, the mutated gene can be molecularly identified.
正向遺傳學篩查是分子遺傳學家最初可使用的一種方法,該技術意在檢定產生特定表型的變異。為了提高變異的速度,常使用誘變劑來實現。而一旦分離出變異體,就可以鑑定出對應的突變基因。