基本情況
個人簡歷
2011年-至今 中國農業大學副教授
2006年-2011年 Kansas State University 博士後
2000年-2005年 南開大學生命科學學院遺傳學專業 博士
1996年-2000年 南開大學生命科學學院生物化學系 學士
教學工作
1. 分子生物學導論 本科生必修課程
2. Basic Biology (英文授課) 本科生必修課程
3. 昆蟲免疫學 研究生選修課程
主要研究方向與項目
研究方向
1. 昆蟲天然免疫反應的分子機制研究
2. 昆蟲天然免疫反應與發育過程的相互關係研究
課題項目
1) 國家自然科學基金面上項目(31172090), 2012-2016年, 主持人
2) 教育部新世紀優秀人才支持計畫(NCET-11-0476), 2013-2015年,主持人
3) 國家“973”計畫項目(2013CB114102),2014-2016年,研究骨幹
4)中國農業大學人才引進科研啟動項目,2011-2014年,主持人
5)中央高校基本科研業務費資金項目(2011JS073),2011年-2012年,主持人
主要學術論文與獲獎
論文著作(*為通訊作者)
1) He, B., Chu, Y., Yin, M.*, Müllen, K., An, C.*, Shen, J*. (2013) Fluorescent nanoparticle delivered dsRNA toward genetic control of insect pests. Adv. Mater. DOI: 10.1002/adma.201301201 (IF: 14.829)
2) An, C.*, Zhang, M., Chu, Y., Zhao, Z.*. (2013) Serine protease MP2 activates prophenoloxidase in the melanization immune response of Drosophila melanigaster. PLos One, DOI: 10.1371/ journal.pone.0079533 (IF: 3.73)
3) Zhang, M., Zhou, F., Chu, Y., Zhao, Z., An, C*. (2013) Identification and expression profile analysis of antimicrobial peptide/protein in Asian corn borer, Ostrinia furnacalis (Gunée), Int. J. Biol. Sci. 9(9): 1004-1012. (IF: 3.168)
4) An, C., Fei, X., Chen, W., Zhao, Z.*. (2012) The integrative effects of population density, photoperiod, temperature, and host plant on the induction of alate aphids in Schizaphis graminum. Arch. Insect Biochem. 79(4):198-206.
5) An, C., Hiromasa, Y., Zhang, X., Lovell, S., Zolkiewski, M., Tomich, JM., Michel, K.*. (2012) Biochemical characterization of Anopheles gambiae SRPN6, a malaria parasite invasion marker in mosquitoes. PLos one. 7(11): e48689.
6)An, C., Budd, A., Kanost, M.R., Michel. K*., (2011) Characterization of a regulatory unit that controls melanization and affects longevity of mosquitoes. Cel. Mol. Life Sci. 68(11):1929-1939.
7)An, C., Ragan, E. J., Kanost, M. R*. (2011) Serpin-1 splicing isoform J inhibits the proSpätzle-activating proteinase HP8 to regulate expression of antimicrobial hemolymph proteins in Manduca sexta. Dev. Comp. Immunol. 35, 135-141.
8)An, C, Lovell, S., Kanost, M.R., Battaile, K. P., Michel, K*. (2011) Crystal structure of native Anopheles gambiae Serpin-2, a negative regulator of melanization in mosquitoes. Proteins. 79(6), 1999-2003.
9)Ragan, E.J., An, C. (Co-first author), Yang, C., Kanost, M.R. (2010) Analysis of mutually-exclusive alternatively spliced serpin-1 isoforms and identification of Serpin-1 proteinase complexes in Manduca sexta hemolymph. J. Biol. Chem. 285(38): 29642-29650.
10)An, C., Kanost, M.R. (2010) Manduca sexta serpin-5 regulates prophenoloxidase activation and the Toll signaling pathway by inhibiting hemolymph proteinase HP6. Insect Biochem. Mol. Biol. 40, 683-689.
11)An. C, Jiang, H., Kanost, M.R. (2010) Proteolytic activation and function of the cytokine Spätzle in the innate immune response of a lepidopteran insect, Manduca sexta. FEBS J. 277, 148-162.
12)An. C., Ishibashi, J., Ragan, E.J., Jiang, H., Kanost, M.R. (2009) Functions of Manduca sexta hemolymph proteinases HP6 and HP8 in two innate immune pathways. J. Biol. Chem. 284, 19716-19726.
13)Ragan, E.J., An, C., Jiang, H., Kanost, M.R. (2009) Roles of haemolymph proeins in antimicrobial defences of Manduca sexta. In: Insect Infection and Immunity (J. Rolff and S. E. Reynolds, eds) pp34-48, Oxford University Press. (Book)
14)Pinto, S.B., Lombardo, F., Koutsos, A.C., Waterhouse, R. M., McKay, K., An, C., Ramakrishnan, C., Kafatos, F. C., Michel, K. (2009) Discovery of Plasmodium modulators by genome-wide analysis of circulating hemocytes in Anopheles gambiae. PNAS. 106, 21270-21275.
15)Gorman, J., An, C., Kanost, M.R. (2007) Characterization of tyrosine hydroxylase from Manduca sexta. Insect Biochem. Mol. Biol. 37, 1327-1337. (IF: 3.12)
獎勵情況
2011年入選教育部“新世紀優秀人才支持計畫”