主要內容
分子生物學與分子遺傳學領域正經歷著日新月異的變化，每天都會出現新的數據，那些熱門的研究進程，過去每隔數年才會出現新的見解和看法，現在只要幾周或幾個月。在過去幾十年里，對廣大教學者來說，Lewin的《基因》是一本十分優秀的教材，該書對分子生物學和分子遺傳學進行了精彩的論述，內容涵蓋了基因的結構、序列、組織和表達。基因x》在內容上增加了一些新的章節，結構也進行了一些調整，使得全書各個主題在排列上更加富有邏輯性。另外許多章節也重新命名，和內容更加相符。新版中還包含了一些新的教學特色，便於學生在閱讀《基因X》過程中更好地學習；增加一個線上學習導航，學生可以使用它對關鍵內容進行自我測試。
新版特色
全新的第3章——分子生物學和基因工程方法，詳細介紹了分子生物學實驗技術的概念和實踐。
新插入的第8章——基因組進化，對於早期版本分散在各章節中的相關材料做了整合、擴展和更新，並介紹了一些新進展。
第22章——mRNA的穩定性和定位，完全更新並重寫，以包含更多的前沿內容。
第30章——調控RNA和小RNA，特別引入了RNA通路的相關內容。
大量嶄新的精美插圖反映了相關領域的新進展，尤其是基閃組結構和功能、表觀遺傳學，以及原核生物中非編碼和小RNA的調控。
圖書目錄
Contents
Preface
xxPart 1. GENES AND CHROMOSOMES 1
Chapter 1. Genes Are DNA 2Chapter 2.
Genes Code for Proteins 26
Edited by Esther Siegfried, Pennsylvania State University, Altoona
Chapter 3. Methods in Molecular Biology andGenetic Engineering 42
Edited by John Brunstein, University of British Columbia
Chapter 4. The Interrupted Gene 79
Edited by Donald Forsdyke, Queens University
Chapter5. The Content of the Genome 98
Chapter 6. Genome Sequences and GeneNumbers 118
Chapter 7. Clusters and Repeats 139
Chapter 8. Genome Evolution 159
Chapter 9. Chromosomes 189
Edited by Hank W. Bass, Florida State University
Chapter 10. Chromatin 220
Part 2. DNA REPLICATIONAND RECOMBINATION 262
Chapter 11. The Replicon 263
Edited by Stephen D. Bell, Oxford University
Chapter 12. Extrachromosomal Replicons 282
Edited by Sgren Johannes Serensen & lars Hestbjerg Hansen, University of Copenhagen
Chapter 13. Bacterial Replication Is Connectedto the Ceil Cycle 299
Edited by Barbara Funnell, University of Toronto
Chapter 14. DNA Replication 320
Edited by Peter Burgers, Washington University Medical School
Chapter 15. Homologous and Site-SpecificRecombination 348
Edited by Hannah L. Klein & Samantha Hoot, New York University Langone Medical Center
Chapter 16. Repair Systems 391
Chapter 17. Transposable Elementsand Retroviruses 419
Edited by Damon Lisch, University of California,Berkeley
Chapter 18. Somatic Recombination andHypermutation in the Immune System 458
Edited by Paolo Casali, Institute for Immunology,University of California, Irvine
Part 3. TRANSCRIPTIONAN D POSTrRANSCRIPTIONALMECHANISMS 503
Chapter 19. Prokaryotic Transcription 504
Edited by Richard Gourse, University of Wisconsin, Madison
Chapter 20. Eukaryotic Transcription 546
Chapter 21. RNA Splicing and Processing 573
Edited by Xiang-Dong Fu, University of California,San Diego, School of Medicine
Chapter 22. mRNA Stability andLocalization 618
Edited by Ellen Baker, University of Nevada, Reno
Chapter 23. Catalytic RNA 642
Edited by Douglas ,7. Briant, University of Victoria
Chapter 24. Translation 665
Edited by Cheryl Keller Capone, Pennsylvania State University
Chapter 25. Using the Genetic Code 704
Edited by John Perona, University of California, Santa Barbara
Part 4. GENE REGULATION 734Chapter 26. The Operon 735
Edited by Liskin Swint-Kruse, University of Kansas School of Medicine
Chapter 27. Phage Strategies 767
Chapter28.Eukaryotic TranscriptionRegutation 795
Chapter 29. Epigenetic Effects AreInherited 828
Edited by Trygve ToUefsbol, University of Alabama, Birmingham
Chapter 30. Regutatory RNA 861
Gtossary 881
Index 905
