工作經歷
美國密西根大學醫學院,博士後,1995-1997美國史丹福大學醫學院,博士後,1997-1999
香港科技大學生物化學系,研究助理,2000-2003
清華大學生命科學學院,副教授,2004-至今
研究興趣、領域
蛋白質之間的相互作用與功能,真核生物基因表達的調控以及脂聯素多聚體形成和分泌的調控機制
所開設的課程:
生物化學(2)(英文)
著作論文
Huang, Z., T. Cui, J. Liu, Y. Zhuang, Q. Meng, L, Tao, and Z. Li. 2008. Characterization of the expression of CTRP9, a paralog of adiponectin. Tsinghua Sci and Tech. 13: 492-499.
Li, Z., G. David, K-W. Hung, R. A. DePinho, A. K. Y. Fu, and N. Y. Ip. 2004. Cdk5/p35 phosphorylates mSds3 and regulates mSds3-mediated repression of transcription. J. Biol. Chem. 279: 54438-54444.
Cheng, K*, Z. Li*, W-Y. Fu, J. H. Wang, A. K. Y. Fu, and N. Y. Ip. 2002. Pctaire1 interacts with p35 and is a novel substrate for Cdk5/p35. J. Biol. Chem. 277: 31988-31993. *These authors contributed equally to this work.
Li, Z., C. A. Karlovich, M. P. Fish, M. P. Scott, and R. M. Myers. 1999. A putative Drosophila homolog of the huntington disease gene. Hum. Mol. Genet. 8:1807-1815.
Shelbourne, P. F., N. Killeen, R. F. Hevner, H. M. Johnston, L. Tecott, M. Lewandoski, M. Ennis, L. Ramirez, Z. Li, C. Iannicola, D. R. Littman, and R. M. Myers. 1999. A Huntington’s disease CAG expansion at the murine Hdh locus is unstable and associated with behavioural abnormalities in mice. Hum. Mol. Genet. 8:763-774.
Li, Z. and G. J. Nabel. 1997. IkB-e, a new member of the IkB protein family, inhibits RelA (p65)-mediated NF-kB transcription. Mol. and Cell. Biol. 17:6184-6190.
Li, Z., A.G. Paulovich, and J.L. Woolford, Jr. 1995. Feedback inhibition of the yeast ribosomal protein gene CRY2 is mediated by the nucleotide sequence and secondary structure of CRY2 pre-mRNA. Mol. and Cell. Biol. 15:6454-6464.
Paulovich, A.G., J.R. Thompson, J.C. Larkin, Z. Li, and J.L. Woolford, Jr. 1993. Molecular genetics of cryptopleurine resistance in Saccharomyces cerevisiae: expression of a ribosomal protein gene family. Genetics 135:719-730.
榮譽、獎勵
2004年入選教育部“新世紀優秀人才支持計畫”
2008年榮獲北京市總工會授予的”北京市教育創新標兵”稱號