概述
劉汝濤教授1972年1月生,山東沂水人,中共黨員,教授,理學博士,博士生導師。
2002年6月畢業於山東大學化學與化工學院,獲理學博士學位。同年6月赴美國Yeshiva大學愛因斯坦醫學院生理與生物物理系,從事博士後研究,師從國際著名生物物理學家Mark R. Chance教授。2005年9月作為高層次優秀人才引入山東大學環境科學與工程學院工作。
近年來主要利用PCR擴增、基因序列分析,凝膠電泳,光譜技術,電視顯微電泳技術,液相色譜-質譜聯用技術等手段從事小分子與蛋白質、核酸相互作用及大分子結構、功能及環境污染與健康領域的研究工作。已發表論文38篇,其中第一作者SCI論文25篇,單篇論文影響因子達9.624。本人發表的論文已被Cell;acct. Chem. Res.; Mol. Cell & Proteomics等國際著名刊物引用200餘次。
學術兼職:
美國質譜學會成員紐約自然科學院成員
國際生物物理學會成員
美國生物化學與分子生物學學會成員
美國Brookhaven國家重點實驗室客座研究員
Biochime等國際著名學術榜刊物的稿件特約評審員
當前研究領域:
環境污染與健康:主要包括環境化學污染物對機體的損傷、致病以及污染物在蛋白質和/或基因分子水平上的毒性作用機理、關鍵修復技術及預防對策等的研究;環境分析化學:開發環境化學污染物的高靈敏度、高選擇性監測方法,研究環境化學污染物在環境、機體中的存在形態、遷移轉化與富集規律及生物標誌物等領域的研究;
持久性有機污染物降解機理及工藝:探討持久性有機污染物的高級氧化降解機理,開發高效率、低能耗的降解工藝;
清潔發展機制(CDM);清潔生產技術及工藝(CP Technology)。
主講課程:
《環境毒理學》,《環境化學》,《環境檢測》,《專業英語》等。科研獎勵:
1.國際獎勵:2002年獲國際技術教育委員會傑出論文獎。2.省級獎勵:2001年獲山東省優秀碩士學位論文獎;
2000年獲“挑戰杯”山東省一等獎。
3.校級獎勵:1998年獲山東大學校長獎學金;
2000年被評為山東大學學生科技創新先進個人;
2001年獲山東大學最高額獎學金—立青獎學金;
2003年獲山東大學優秀博士學位論文獎。
資格證書:
2002年獲美國Yeshiva大學愛因斯坦醫學院環境健康與安全評價證書;2004年獲美國Yeshiva大學愛因斯坦醫學院廢棄物處理與安全評價證書;
2005年獲美國Yeshiva大學愛因斯坦醫學院生理與病理學培訓證書;
2005年獲美國質譜學會培訓證書。
代表性學術論文:
1. Rutao Liu, Olga Zak, Philip Aisen, Mark R. Chance, “Structure of full-length transferrin-transferrin receptor and the iron transportation mechanism with toxicology”, 2006, (In Preparation)2. Lijun Ren, Xueliang Yuan, Rutao Liu*, “Research on method development during the strategic environmental assessment”, Stoch Environ Res Risk Assess, 2006, (SCI, 電子版已發表)
3. Hua Sui, Gang Zheng, Yuanyuan Zhang, Rutao Liu*, Ganzuo Li, “Synthesis of Ferromagnetic in Detergent Solution”, J Dispersion Science Technology,2006,27(3):311-315(SCI)
4. Guozhong Xu, Rutao Liu, Olga Zak, Philip Aisen, Mark R. Chance, “Structural Allostery and Binding of the Transferrin-Receptor Complex”, Mol. & Cellular Proteomics, 2005,4(12): 1959-1967(並列第一作者,影響因子Ip=9.624,該研究成果被選為刊物的封面重點介紹)
5. Rutao Liu, Jinghe Yang, Changxai Sun, Xia Wu, Zengjun Lan, Tao Wu, “Resonance Double Light Scattering Method for the Determination of Nucleic Acids with Cetylpyridine Bromide”, Mikrochimica Acta, 2004, 147(1-2): 105-109. (SCI)
6. Rutao Liu, Jinghe Yang, Changxia Sun, Xia Wu, Lei Li and Benyu Su, “Study on the interaction between nucleic acids and cationic surfactants”, Colloids and surfaces B-Biointerfaces, 2004, 34(1): 59-63. (SCI)
7. Rutao Liu, Jing-Qu Guan, Olga Zak, Philip Aisen, Mark R. Chance, “Structural Reorganization of the Transferrin C-lobe: Transferrin C-lobe Binds to the Receptor Helical Domain”, Biochemistry, 2003, 42: 12447-12454 (Accelerated Publication; Cell, 2004,116: 483-489, Preview 及Cell, 2004,116: 565-576對該成果專門評論; Ip=4.064).
8. Rutao Liu, Jinghe Yang, Changxia Sun, Lei Li, Xia Wu, Zhengmin Li, Chuansong Qi, “Study ofthe interaction of nucleic acids with acridine orange-CTMAB and determination of nucleic acids at nanogram levels based on the enhancement of resonance light scattering”, Chemical Physics Letters, 2003, 376: 108-115.(Ip=2.438)
9. Rutao Liu, Jinghe Yang, Changxia Sun, Xia Wu, Lei Li, Zhengmin Li, “Resonance light-scattering method for the determination of BSA and HSA with sodium dodecyl benzene sulfonate or sodium lauryl sulfate”, Analytical and Bioanalytical Chemistry, 2003, 377(2): 375-379. (Ip=2.098)
10. Rutao Liu, Jinghe Yang, Xia Wu, “Study of the interaction between nucleic acid and oxytetracycline- Eu3+ and its analytical application”, J. Lumin., 2002, 96: 201-209. (SCI)
11. Rutao Liu, Jinghe Yang, Xia Wu, Zhengmin Li, Fang Huang, “Resonance Rayleigh Light -scattering of Thiamine Hydrochloride-nucleic acid-CTMAB systems and their analytical application”, Journal of Trace and Microprobe Techniques, 2002, 20(3), 363-376. (SCI)
12. Rutao Liu, Jinghe Yang, Xia Wu, Zengjun Lan “Resonance Double Light Scattering Method for the Determination of Proteins with Morin-CTMAB”, Spectrochim. Acta, Part A, 2002, 20(3), 363-376. (SCI)
13. Rutao Liu, Jinghe Yang, Xia Wu, Changxia Sun, “Study on the Resonance Light Scattering Spectrum of Berberine-Cetyltrimethylammonium Bromide System and the Determination of Nucleic Acids at Nanogram Levels”, Spectrochim. Acta, part A, 2002, 58/3:459-467 (SCI)
14. Rutao Liu, Jinghe Yang, Xia Wu, “Interaction of cetyl pyridine bromide with nucleic acids and determination of nucleic acids at nanogram levels based on the enhancement of resonance Rayleigh light scattering”, Spectrochimica Acta Part A, 2002, 58(9): 1935-1942. (SCI)
15. Rutao Liu, Canzhu Gao, Jinghe Yang, “Study on the High corrosion Resistance and Long Life-span Process of Electroless Nickel”, Metal Finishing, 2002, 100(3): 34-37. (EI)
16. Rutao Liu, Jinghe Yang, Xia Wu, Changxia Sun, Tao Wu, “Interaction of Morin-CTMAB with Nucleic Acids and Determination of Nucleic acids at Nanogram Per milliliter Levels Based on the Enhancementof Preresonance Light Scattering”, The Analyst, 2001, 126:1367-1371. (Ip=2.789)
17. Rutao Liu, Jinghe Yang, Xia Wu, Tao Wu, “Resonance double frequency light scattering of morin- nucleic acid-CTMAB system and their analytical application”, Analytical Chimica Acta, 2001, 448(1-2):85-91. (Ip=2.588)
18. Rutao Liu, Jinghe Yang, Xia Wu, Changxia Sun, “Interaction of CTMAB with nucleic acids and determination of nucleic acids at nanogram levels based on the measurement of light scattering”, Analytical Chimica Acta, 2001,441/2:303-308. (Ip=2.588)
19. Rutao Liu, Jinghe Yang, Xia Wu, Sui Hua, Changxia Sun, “Interaction of morin with CTMAB: Aggregation and location in micellar”, Spectrochim. Acta, Part A, 2001, 57/13:2561-2566. (SCI)
20. Rutao Liu, Jinghe Yang, Xia Wu, Changxia Sun, “Simple and sensitive determination of nucleic acid by Rayleigh light scattering technique with methyl green-CTMAB”, Indian J. of Chem., 2001, 40A: 1121-1123. (SCI)
21. Rutao Liu, Canzhu Gao, Sui Hua, Yanqing Feng, Jinghe Yang, “Rapid spectrometric Determination of Ni2+ in Electroless Nickel Deposition Baths Containing Fe”,Platingand Surface Finishing, 2001, 88(9): 80-83. (SCI)
22. Rutao Liu, Guan, J-Q., Aisen, P., Chance, M.R. “Human Transferrin Binding Sites with Transferrin Receptor Detected by Hydroxyl Radical Footprinting and Mass Spectrometry”,Biophysical Journa,2004, 86: 96a. (SCI)
23. Chance, M.R., Zak, O., Aisen, P., Rutao Liu, and J-Q.Guan, “Structure of Transferrin: Receptor Complex as Analyzed by Footprinting and Mass Spectrometry”, J. Am. Soc. Mass Spectrometry, 2004, 15:63S. (SCI)
24. Rutao Liu, Zak, O., Aisen, P., Chance, M.R.,“Structural Reorganization of Transferrin C-Lobe and Transferrin Receptor Upon Complex Formation: C-Lobe Binds to the Receptor Helical Domain”, Mol. & Cellular Proteomics, 2003, 2.9 supplement, 45.1. (SCI)
25. Rutao Liu., Aisen, P., Zak, O., Chance, M.R., “Synchrotron Hydroxyl Radical Footprinting and Mass Spectrometry Method to Probe the Surface of Human Transferrin C-Lobe”, Biophysical Journal, 2003, 84: 36A. (SCI)
26. Rutao Liu, Canzhu Gao, Sui Hua, Jinghe Yang, Yuli Lu,“Derivation and RapidSpectrophotometric Determination of iron in Electroless NickelPlating solution”, Plating andSurface Finishing, 2000,87(2): 73-77. (SCI)
27. Rutao Liu, Canzhu Gao, and Yuli Lu, “Study on a medium speed and long life-span electroless nickel plating process”, Transactions of the Institute of Metal Finishing ,2000, 78(5): 198-200. (SCI)
28. Cunguo Lin, Jinghe Yang, Xia Wu, Guiling Zhang, Rutao Liu, Xihui Cao, Rongjiang Han, “Enhanced fluorescence of the terbium-gadolinium-nucleic acids system and the determination of nucleic acids”, Anal. Chim. Acta, 2000, 403:219- 224. (SCI)
29. Fang Huang, Jinghe Yang, Aiyou Hao, Xia Wu, Rutao Liu,Quanli Ma, “The Study of Spectrographic Properties and Molecular Recognition of Calix【n】arenes”, Spectrochim. Acta, Part A, 2001, 57:1025-1030. (SCI)
30. Canzhu Gao, Yuli Lu, Rutao Liu, “Influence of Additives on Electrodeposition of Nickel from a Watts Bath-a Cyclic Voltammetric study”, Plating and Surface Finishing, 1997, 84(9):83-85. (SCI)
31. 劉汝濤, 馮雁卿,高燦柱, 楊景和,“化學鍍鎳清潔生產工藝的研究”,化工環保, 2001, 3:164-167.
32. 劉汝濤, 高燦柱, 楊景和,鹿玉理,“化學鍍鎳液中NaH2PO2的快速測定”,,電鍍與環保, 2000, 20(1),29-31.
33. 劉汝濤, 張繼有, 高燦柱, 鹿玉理,“化學鍍鎳穩定性因素的研究”,表面技術,2001,31(1): 10-12.
34. 劉汝濤, 高燦柱, 鹿玉理,“化學鍍鎳添加工藝的研究”,電鍍與環保,1998,18(5):19-21.
35. 劉汝濤, 高燦柱, 隋華, 鹿玉理,“化學鍍鎳液中鎳離子濃度得快速測定”,材料保護,1998, 31(10):25-27.
36. 劉汝濤, 高燦柱, 隋華, 鹿玉理,“化學鍍鎳液中絡合劑濃度的快速測定”,電鍍與精飾, 1998, 20,(6):33-36.
37. 李懷納, 畢思偉, 劉汝濤, “N-亞水楊基亮氨酸3d金屬配合物的合成及薄層色譜與紫外光譜研究”, 色譜, 1997,15(5):425-427.