![肖義[大連理工大學精細化工國家重點實驗室教授]](/img/3/59e/nBnauM3X2IjN2MjNwMzN0ETN1UTM1QDN5MjM5ADMwAjMwUzLzczL4IzLt92YucmbvRWdo5Cd0FmLwE2LvoDc0RHa.jpg "肖義[大連理工大學精細化工國家重點實驗室教授]")
教育背景
1992, 09-1996, 07, 天津大學套用化學系精細化工專業, 本科生;
1996, 09-1999, 03, 天津大學化工學院精細化工專業， 碩士生。
1999, 03-2003, 02, 大連理工大學精細化工系套用化學專業， 博士生；
工作經歷
2003, 03-2004, 01, 日本國立產業技術綜合研究所博士後研究員；
2004, 01 -2005, 05， 大連理工大學精細化工系，講師;
2005, 06 - 2009,12， 大連理工大學精細化工系，副教授;
2009,12 至今 大連理工大學精細化工國家重點實驗室，教授;
研究領域
肖義教授領導的課題組主要從事螢光染料、分子探針、有機光電功能材料等方面的研究工作。旨在設計合成結構新穎、高效、多功能螢光發色團；開發高靈敏度、高選擇性、具有生物學實用性的分子探針；套用螢光發色團開發高效電致發光、有機固體染料雷射器、有機半導體等功能材料(主要包括有機薄膜太陽能電池材料\有機場效應電晶體材料)。
承擔項目
1）負責人：肖義。項目名稱：結構新穎的有機氟硼配合物類強螢光發色團家族的創製於發光性能研究；國家自然科學基金(20876022)， 起止時間2009.01-2011.12。經費35萬。
2）負責人：肖義。項目名稱：苊並吡咯類新雜環及其芳香氫親核取代反應：長波長螢光探針的開發與生物學套用；國家自然科學基金(20572012)， 起止時間2006.01-2008.12。經費26萬。
3）負責人：肖義。項目名稱：萘醯亞胺通過鍵光誘導電子轉移螢光分子開關的創製；國家自然科學基金(20406004)， 起止時間2005.01-2007.12。經費23萬。
4）負責人：錢旭紅。排序：錢旭紅、楊青、肖義、徐玉芳、徐曉勇 等。項目名稱：色素衍生的生物客體探針與藥物先導；國家自然科學基金重點項目(20536010)， 起止時間2005.01-2009.12。總經費180萬，個人承擔38萬。
5）負責人：肖義。2008年度“教育部新世紀優秀人才支持計畫”，經費50萬。
碩博研究方向
螢光染料與螢光分子探針
分子與聚合物有機半導體材料與器件
光電轉換功能性色素
代表論文
41.Regioselective Photocyclization To Prepare Multifunctional Blocks for Ladder-Conjugated Materials
Zhenbo Zhao, Youdi Zhang, and Yi Xiao*
J. Org. Chem., 2013, 78 (11), pp 5544–5549
DOI: 10.1021/jo400619u
40.Synthesis of tetraalkyl naphthalene bisanhydride and its model condensations with amines
Kai Xiong, Yi Xiao*
Tetrahedron Letters Volume 54, Issue 24, 12 June 2013, Pages 3171–3175
39.From a BODIPY–rhodamine scaffold to a ratiometric fluorescent probe for nitric oxide
Haibo Yu, Liji Jin,* Yong Dai,* Huaqiang Li and Yi Xiao*
New J. Chem., 2013,37, 1688-1691
DOI: 10.1039/C3NJ41127C
38.Activatable Rotor for Quantifying Lysosomal Viscosity in Living Cells
Lu Wang, Yi Xiao*, Wenming Tian, and Liezheng Deng
J. Am. Chem. Soc., 2013, 135 (8), pp 2903–2906
DOI: 10.1021/ja311688g
37.MODULATION OF FRET THROUGH THE SPECTRAL-OVERLAP STRATEGY
Haibo Yu, Yi Xiao*
Journal of Innovative Optical Health Sciences Volume 05, Issue 03, July 2012
36.meso-Alkoxy BODIPYs with a good balance between larger Stokes shifts and higher fluorescence quantum yields
Lu Wang,Yuhui Zhang and Yi Xiao*
RSC Adv., 2013,3, 2203-2206
DOI: 10.1039/C2RA21920D
35.N-type organic semiconductor bisazacoronene diimides efficiently synthesized by a new type of photocyclization involving a Schiff base
Youdi Zhang, Zhenbo Zhao, Xiaomei Huang, Yuanpeng Xie, Chenxi Liu, Jun Li, Xin Guan, Kaichen Zhang, Chuanhui Cheng* and Yi Xiao*
RSC Adv., 2012,2, 12644-12647
DOI: 10.1039/C2RA22488G
34.Synthesis and Optical and Redox Properties of Symmetric and Asymmetric BODIPYs
Inmaculada García-Moreno, Lu Wang, Angel Costela1, Jorge Bauelos*, Iigo López Arbeloa, Yi Xiao*
ChemPhysChem Volume 13, Issue 17, pages 3923–3931, December 7, 2012
DOI: 10.1002/cphc.201200587
33.A Lysosome-Targetable and Two-Photon Fluorescent Probe for Monitoring Endogenous and Exogenous Nitric Oxide in Living Cells
Yu, Haibo, Xiao, Yi*, Jin, Liji
J. Am. Chem. Soc., 2012, 134 (42), pp 17486–17489
DOI: 10.1021/ja308967u
32.From Spirolactam Mixtures to Regioisomerically Pure 5- and 6-Rhodamines: A Chemodosimeter-Inspired Strategy
Haibo Yu , Yi Xiao *, and Haiying Guo
Org. Lett., 2012, 14 (8), pp 2014–2017
DOI: 10.1021/ol300523m
31.Fusing three perylenebisimide branches and a truxene core into a star-shaped chromophore with strong two-photon excited fluorescence and high photostability
Yuanpeng Xie, Xinfu Zhang, Yi Xiao*, Youdi Zhang, Fan Zhou, Jing Qib and Junle Qu*
Chem. Commun., 2012,48, 4338-4340
DOI: 10.1039/C2CC31261A
Received 20 Feb 2012, Accepted 07 Mar 2012
First published online 08 Mar 2012
30.Replacing Phenyl Ring with Thiophene: An Approach to Longer Wavelength Aza-dipyrromethene Boron Difluoride (Aza-BODIPY) Dyes
Xinfu Zhang, Haibo Yu, and Yi Xiao*
J. Org. Chem., 2012, 77 (1), pp 669–673
DOI: 10.1021/jo201413b
Publication Date (Web): November 23, 2011
29.Soluble Ladder Conjugated Polymer Composed of Perylenediimides and Thieno[3,2-thiophene (LCPT): A Highly Efficient Synthesis via Photocyclization with the Sunlight
Zhongyi Yuan, Yi Xiao*, Yang Yang and Tao Xiong
Macromolecules, 2011, 44 (7), pp 1788–1791
DOI: 10.1021/ma1026252
Publication Date (Web): March 4, 2011
28.Convenient and Efficient FRET Platform Featuring a Rigid Biphenyl Spacer between Rhodamine and BODIPY: Transformation of ‘Turn-On’ Sensors into Ratiometric Ones with Dual Emission
Haibo Yu, Yi Xiao*, Haiying Guo, Xuhong Qian*
Chemistry - A European Journal
Volume 17, Issue 11, pages 3179–3191, March 7, 2011
Article first published online: 10 FEB 2011
DOI: 10.1002/chem.201002498
27.Fused perylenebisimide–carbazole: new ladder chromophoreswith enhanced third-order nonlinear optical activities
Yang Yang, Yaochuan Wang, Yuanpeng Xie, Tao Xiong, Zhongyi Yuan, Youdi Zhang, Shixiong Qian and Yi Xiao*
Chem. Commun., 2011,47, 10749-10751
DOI: 10.1039/C1CC14071J
Received 07 Jul 2011, Accepted 15 Aug 2011
First published online 25 Aug 2011
26.Unprecedented laser action from energy transfer in multichromophoricBODIPYcassettes
Yi Xiao*, Dakui Zhang, Xuhong Qian*, Angel Costela, Inmaculada Garcia-Moreno*, Virginia Martin, M. Eugenia Perez-Ojeda, Jorge Bauelos*, Leire Gartziad and Iigo López Arbeload
Chem. Commun., 2011,47, 11513-11515
DOI: 10.1039/C1CC13874J
Received 29 Jun 2011, Accepted 01 Sep 2011
First published online 20 Sep 2011
25.Development of excellent long-wavelength BODIPY laser dyes with a strategy that combines extending π-conjugation and tuning ICT effect
Dakui Zhang, Virginia Martín,* Inmaculada García-Moreno, Angel Costel, M. Eugenia Pérez-Ojed and Yi Xiao*
Phys. Chem. Chem. Phys., 2011,13, 13026-13033
DOI: 10.1039/C1CP21038F
Received 04 Apr 2011, Accepted 31 May 2011
First published online 21 Jun 2011
24.Nonlinear optical properties and ultrafast dynamics of three novel boradiazaindacene derivatives
Yaochuan Wang; Zhang, Dakui ; Hui Zhou ; Jinliang Ding ; Qiang, Chen ; Yi Xiao*;Shixiong Qian
JOURNAL OF APPLIED PHYSICSvolumn:108(3) DOI:10.1063/1.3457859 AUG 1 2010
23.Core-Perfluoroalkylated Perylene Diimides and Naphthalene Diimides: Versatile Synthesis, Solubility, Electrochemistry, and Optical Properties
Zhongyi Yuan , Jing Li , Yi Xiao , Zheng Li and Xuhong Qian
J. Org. Chem., 2010, 75 (9), pp 3007–3016
DOI: 10.1021/jo100231j
Publication Date (Web): April 5, 2010
22.Red-edge laser action from borondipyrromethene dyes
Garcia-Moreno, Inmaculada ; Zhang, Dakui; Costela, Angel; Martin, Virginia ; Sastre, Roberto; Xiao, Yi*
Journal of Applied Physics (Volume:107 , Issue: 7 ) Page(s):073105 - 073105-7
Date of Publication: Apr 2010
http://dx.doi.org/+10.1063/1.3327437
21.A design concept of planar conjugated ladder oligomers of perylenebisimides and efficient synthetic strategy <em>via</em> regioselective photocyclization
Zhongyi Yuan, Yi Xiao* and Xuhong Qian*
Chem. Commun., 2010,46, 2772-2774
DOI: 10.1039/B925605A
Received 08 Dec 2009, Accepted 09 Feb 2010
First published online 25 Feb 2010
20.“Alive” dyes as fluorescent sensors: fluorophore, mechanism,receptorand images in livingcells
Xuhong Qian,* Yi Xiao, Yufang Xu, Xiangfeng Guo, Junhong Qian and Weipin Zhua
Chem. Commun., 2010,46, 6418-6436
DOI: 10.1039/C0CC00686F
Received 31 Mar 2010, Accepted 18 May 2010
First published online 29 Jun 2010
19.Switching off FRET byanalyte-induceddecompositionofsquaraineenergy acceptor: A concept to transform ‘turn off’ chemodosimeter into ratiometric sensors
Haibo Yu, Meiyan Fua and Yi Xiao*
Phys. Chem. Chem. Phys., 2010,12, 7386-7391
DOI: 10.1039/C001504K
Received 22 Jan 2010, Accepted 18 May 2010
First published online 10 Jun 2010
18.Novel acenaphtho[1,2-<em>b</em>]pyrrole-carboxylic acid family: Synthesis, cytotoxicity, DNA-binding and cell cycle evaluation
Lijuan Xie, Yi Xiao, Fang Wang, Yufang Xu, Xuhong Qian*, Rong Zhang, Jingnan Cui, Jianwen Liu*
Bioorganic & Medicinal Chemistry
Volume 17, Issue 21, 1 November 2009, Pages 7615–7621
http://dx.doi.org/10.1016/j.bmc.2009.02.031
17.Long-wavelength boradiazaindacene derivatives with two-photon absorption activity and strong emission: versatile candidates for biological imaging applications
Dakui Zhang, Yaochuan Wang, Yi Xiao*, Shixiong Qian, Xuhong Qian
Tetrahedron
Volume 65, Issue 39, 26 September 2009, Pages 8099–8103
http://dx.doi.org/10.1016/j.tet.2009.08.002
16.Efficient Synthesis of Regioisomerically Pure Bis(trifluoromethyl)-Substituted 3,4,9,10-Perylene Tetracarboxylic Bis(benzimidazole)
Zhongyi Yuan, Yi Xiao*, Zheng Li and Xuhong Qian*
Org. Lett., 2009, 11 (13), pp 2808–2811
DOI: 10.1021/ol9010689
Publication Date (Web): June 9, 2009
15.Bulk heterojunction organic solar cell based on a novel fluorescent fluorine–boron complex
Fen Qiao, Aimin Liu, Ying Zhou, Yi Xiao, Ping Ou Yang
Journal of Materials Science
March 2009, Volume 44, Issue 5, pp 1283-1286
14.Synthesis and characterization offullerenederivatives with perfluoroalkylgroups
Xuemei Wang, Yunlong Guo, Yi Xiao,* Lei Zhang, Gui Yu* and Yunqi Liu*
J. Mater. Chem., 2009,19, 3258-3262
DOI: 10.1039/B823336E
Received 05 Jan 2009, Accepted 05 Mar 2009
First published online 31 Mar 2009
13.Enhanced photovoltaic characteristics of solar cells based on n-type triphenodioxazine derivative
Fen Qiao, Aimin Liu,Yi Xiao, Yang Ping Ou, Ji quan Zhang, Yong chang Sang
Microelectronics Journal
Volume 39, Issue 12, December 2008, Pages 1568–1571
12.Novel angular furoquinolinones bearing flexible chain as antitumor agent: Design, synthesis, cytotoxic evaluation, and DNA-binding studies
Lijuan Xie, Xuhong Qian, Jingnan Cui, Yi Xiao, Kewei Wang, Peichun Wu, Liying Cong
Bioorganic & Medicinal Chemistry
Volume 16, Issue 18, 15 September 2008, Pages 8713–8718
11.Trifluoromethyltriphenodioxazine: Air-Stable and High-Performance n-Type Semiconductor
Chong-an Di , Jing Li , Gui Yu , Yi Xiao , Yunlong Guo , Yunqi Liu , Xuhong Qian and Daoben Zhu
Org. Lett., 2008, 10 (14), pp 3025–3028
DOI: 10.1021/ol8008667
Publication Date (Web): June 12, 2008
10.2,3,6,7-Tetraamino-9,9-bis(2-ethylhexyl)fluorene: New Multifunctional Monomer for Soluble Ladder-Conjugated Molecules and Polymers
Xichuan Li , Yi Xiao and Xuhong Qian
Org. Lett., 2008, 10 (13), pp 2885–2888
DOI: 10.1021/ol801081w
Publication Date (Web): June 3, 2008
9.A highly selective Cd2+sensor of naphthyridine: fluorescent enhancement and red-shift by the synergistic action of forming binuclear complex
Ying Zhou, Yi Xiao, Xuhong Qian
Tetrahedron Letters
Volume 49, Issue 21, 19 May 2008, Pages 3380–3384
8.A design concept of long-wavelength fluorescent analogs ofrhodaminedyes: replacement ofoxygenwithsiliconatom
Meiyan Fu, Yi Xiao,* Xuhong Qian,* Defeng Zhao and Yufang Xu
Chem. Commun., 2008, 1780-1782
DOI: 10.1039/B718544H
Received 30 Nov 2007, Accepted 22 Jan 2008
First published online 14 Feb 2008
7.Versatile Nitro-Fluorophore as Highly Effective Sensor for Hypoxic Tumor Cells: Design, Imaging and Evaluation
Min Dai, Weiping Zhu, Yufang Xu, Xuhong Qian, Yan Liu, Yi Xiao, Yin You
Journal of Fluorescence
March 2008, Volume 18, Issue 2, pp 591-597
6.Isomeric BoronFluorine Complexes with DonorAcceptor Architecture: Strong Solid/Liquid Fluorescence and Large Stokes Shift
Ying Zhou, Yi Xiao,* Shaoming Chi and Xuhong Qian*;
Org. Lett., 2008, 10 (4), pp 633–636
DOI: 10.1021/ol702963w
Publication Date (Web): January 18, 2008
5.Novel Fluorescent FluorineBoron Complexes: Synthesis, Crystal Structure, Photoluminescence, and Electrochemistry Properties
Ying Zhou , Yi Xiao,* Dan Li , Meiyan Fu and Xuhong Qian *
J. Org. Chem., 2008, 73 (4), pp 1571–1574
DOI: 10.1021/jo702265x
Publication Date (Web): January 15, 2008
4.Synthesis, Herbicidal Activity, and Structure-Bioactivity Relationship of Pyridyl-Containing 2-Phenyliminothiazolidines
Gangyue Li, Xuhong Qian, Shenggang Yan, Jingnan Cui, Rong Zhang, Yi Xiao
Monatshefte für Chemie - Chemical Monthly
February 2008, Volume 139, Issue 2, pp 169-178
3.Highly Efficient Energy Transfer in the Light Harvesting System Composed of Three Kinds of BoronDipyrromethene Derivatives
Xiaolin Zhang , Yi Xiao,* and Xuhong Qian
Org. Lett., 2008, 10 (1), pp 29–32
DOI: 10.1021/ol702381j
Publication Date (Web): December 11, 2007
2.A Ratiometric Fluorescent Probe Based on FRET for Imaging Hg2+Ions in Living Cells
Xiaolin Zhang, Yi Xiao, Xuhong Qian
Angewandte Chemie International Edition
Volume 47, Issue 42, pages 8025–8029, October 6, 2008
1.Bulky4-tritylphenylethynylsubstitutedboradiazaindacene: pure red emission, relatively large Stokes shift and inhibition of self-quenching
Dakui Zhang, Yugeng Wen, Yi Xiao,* Gui Yu,* Yunqi Liu and Xuhong Qian*
Chem. Commun., 2008, 4777-4779
DOI: 10.1039/B808681H
Received 22 May 2008, Accepted 30 Jun 2008
First published online 06 Aug 2008
工作成果（獎勵、專利等）
項目名稱“生物功能色素及螢光分子感測器”，獲獎人：錢旭紅，肖義，崔京南，徐玉芳。2008年度上海市自然科學一等獎，省部級獎。獲獎時間：2008年12月。
