個人經歷
1999.09至今，山東大學微生物技術國家重點室教授
1992.09-1999.09，山東大學微生物技術國家重點室副教授
1996.1～9月,芬蘭技術中心生物技術研究所,從事絲狀真菌分子生物學研究。
1993.4～5月; 1991.5～12月, 兩次赴澳大利亞悉尼大學農化系進行合作研究。
1982 年畢業於山東大學生物系 微生物專業。
社會兼職：中國微生物學會分子生物學與生物工程專業委員會委員
研究方向
1 絲狀真菌分子遺傳學與分子生物學
2 木質纖維素降解代謝酶分子生物學
3 海洋低溫適冷酶的酶學與分子生物學
科研成果
承擔和參加了16項國家和省部級有關絲狀真菌遺傳與分子生物學，木質纖維素降解代謝酶分子生物學方向研究課題，在國內外學術刊物上發表論文50餘篇，其中SCI論文13篇。研究成果榮獲：
“纖維素、半纖維素降解代謝酶分子生物學”獲研究山東省科委科技進步三等獎（1999），首位。
參加“微生物對木質纖維素降解機理的研究” 獲國家教育部基礎類一等獎（1999）。
近五年代表性論文
1.Novel Cold-adaptive Penicillium Strain FS010 Secreting Thermo-labile Xylanase Isolated from Yellow Sea. Acta Biochim Biophys Sin (Shanghai). 2006, 38(2):142-9.
2.Antisense Inhibition of Xylitol Dehydrogenase Gene, xdh1, from Trichoderma reesei Letters in Applied Microbiology, 2005, 40(6):424-9.
3 Cloning and expression of the endogucanase gene from cold-adapted bacteria Pseudoalteromonas sp.MB-1. Acta Microbiologica Sinica 2005，1：142－144
4 Novel cellulase profile of Trichoderma reesei strains constructed by cbh1gene replacement with eg3 gene expression cassette. Acta Biochemica et Biophisica. 2004, 36(10):667-672
5.Construction of a yeast one-hybrid system with the xylanase2 promoter from Trichoderma reesei to isolate transcriptional activators. Letters in Applied Microbiology, 2004, 38(4):277-282
6.Purification and characterization of cold-active α-amylase excreted by a strain of marine cold-adaptive Penicillium, Chemical Research in Chinese University, 2004,20(1): 60-64
7 Construct of the recipient strains for the heterologous gene expression system of Trichoderma reesei. MYCOSYSTEMA 2004, 23（2）：248－254
8 preliminary analysis of the function region deletion in xylanase II promoter in Trichoderma reesei Jounal of ShanDong university(Natural Science) 2004，39（2），102-105
9 Construcion of heterogeneous gene expression system of filamentous fungus Trichoderma reesei. Chinese Jounal of Biochemistry and Molecular Biology 2003，19(6): 736－742
10 Molecular characterization of extreme enzymes Isolated from marine exremophiles. Science &Technology Review 2004，9：7－9
11.Cloning and sequence analysis of a mitochondrial gene cluster encodingtwo NADH dehydrogenase subunits and seven tRNA molecules from Trichoderma reesei. Biotechnology Letters 2002, 24:395-399
12.Cloning and sequence analysis of a mitochondrial gene cluster encoding cytochrome C oxidase subunit III from Trichoderma pseudokoningii. DNA Seq. 2002, 13(5): 271-5.
13.Gene Replacement in Trichoderma reesei to Produce Strains with Novel Cellulase Profiles. Biotechnology 2000, The World Congress on Biotechnology, Book of Abstracts Vol. 2, p. 106, Sept. 3-8, 2000, Berlin.
14.Cold adaptation of a mesophilic cellulase, EG III from Trichoderma reesei, by directed evolition. 2001, Science in China, 45(4):337-343
15.Cellulose-binding domain of engoglucanase III from Trichoderma reesei disrupting the structure of cellulose. Biotechnology Letters 2001. 23: 711-715
16.Non-hydrolytic disruption of crystalline structure of by cellulose by cellulose binding domain and linker sequence of cellobiohydrolase I from Penicillium janthinellum. Acta biochimica et biophysica sinica 2001, 33(1):13-18
