教師簡介
主要以真核微生物釀酒酵母（ Saccharomyces cerevisiae ）為模式系統，在基因和蛋白相互作用網路水平探求基因組不穩定性的分子機理，及其與疾病/癌症發生的關係。目前致力於相互作用組學技術構建DNA複製期（即S期）的蛋白質調控網路。代表性論文包括Mol Cell封面文章等。
學習與工作經歷
2009.3- Professor, Department of Microbiology and Immunology,
College of Biological Sciences, China Agricultural University.
2006.8-2009.3 CIRM Senior Research Fellow,
Divisions of Chemistry and Biology, California Institute of Technology, USA.
2004.8-2006.8 Postdoctoral Scholar,
Division of Chemistry and Chemical Engineering, California Institute of Technology, USA.
1997.9-2004.2 Doctor of Philosophy,
Institute of Microbiology, Chinese Academy of Sciences, China.
1992.9-1997.7 Bachelor of Science,
Department of Cell Biology and Genetics, Peking University, China.
研究方向
In budding yeast:
Genome instability, Diseases and Cancer.
DNA replication and the S phase checkpoint.
DNA damage and replication stress signaling pathways.
Asymmetric segregation and cell aging.
In herperthermophilic archaea:
Genome stability under boiling growth temperature.
Epigenetic adaptation to the extremely harsh environment
主講課程
研究生課程
《Progress in Microbiology》
《Advanced Progress in Microbiology》
《文獻研讀》
發表文章
Huiqiang Lou, Makiko Komata, Yuki Katou, Zhiyun Guan, Clara C. Reis, Martin Budd, Katsuhiko Shirahige, and Judith L. Campbell*. Mrc1 and DNA polymerase ε function together in linking DNA replication and the S phase checkpoint. Mol. Cell 2008, 32(1):106-117. (On the cover).
[Previews] Labib Karim, Making Connections at DNA Replication Forks: Mrc1 Takes the Lead. Mol. Cell, 2008, 32(2):166-168.
Huiqiang Lou, Zhenhong Duan, Tong Sun, and Li Huang*. Cleavage of double-stranded DNA by the intrinsic 3’-5’ exonuclease activity of DNA polymerase B1 from the hyperthermophilic archaeon Sulfolobus solfataricus at high temperature. FEMS Microbiol. Lett. 2004, 231: 111-117.
Huiqiang Lou, Zhenhong Duan, Xiaofeng Huo, and Li Huang*. Modulation of hyperthermophilic DNA polymerase activity by archaeal chromatin proteins. J Biol. Chem. 2004, 279(1):127-32.
Likui Zhang, Huiqiang Lou, et. al. Extremophile. Published online: 11 December 2009
盤點農業部重點實驗室主任之二
| 根據《農業部重點實驗室管理辦法》的有關規定，經研究，農業部同意聘任林敏等228位專家為農業部重點實驗室主任，讓我們來盤點一下這些專家。 |
