簡介
出生年月: 1939年5月
職稱: 教授
簡歷:
曾任復旦大學生命科學學院院長,國家高技術研究計畫生物技術領域專家委員會委員。現為中國遺傳學會理事,《遺傳》和《遺傳學報》副主編,《生物化學與生物物理學報》及《生物工程學報》編委。
主要研究方向:
1. 新型酵母表達載系統的研究和套用。
2. 以酵母菌為模式生物進行人類基因功能和藥物篩選研究。
獲獎情況
1990年被國家計委、國家教委及中國科學院聯合授予"為國家重點實驗室建設作出重大貢獻的先進工作者"稱號,獲金牛獎。2001年獲國家科委授予的"國家863計畫十五周年先進個人"稱號。2001年獲上海市科技進步二等獎、上海市優秀髮明一等獎。
代表性論文和專著
代表性著作:
1. 《基因表達技術》,主編,科學出版社出版,2001
2. 《基因分子生物學研究進展》,副主編,上海科學技術出版社出版,1992
代表性論文:
1. James R. Broach, Yu-Yang Li, J. Feldman, M. Jayaram, K. A. Nasmyth and J.B.Hicks: Localization and sequence analysis of yeast origins of DNA replication, Cold Spring Harbor Symposium on Quantitative Biology 47:1165-1173, 1982
2 S.Carl Falco, Yu-Yang Li, James R.Broach, David Botstain: Genetic properties of chromosomally integrated 2μplasmid DNA in yeast, Cell, 29:573-584, 1982
3 M.Jayaram, Yu-Yang Li, J.R.Broach: The yeast plasmid 2μencodes components required for its high copy propagation, Cell,34:95-104,19
4 M.Jayaram, Yu-Yang Li, M. Mcleod and J.R.Broach: Analysis of site-specific recombination associated with yeast plasmid 2 micron circle, in Mechanisms of DNA replication and recombination, p.685-694, c 1983 Alan R Liss,Inc., 1983
5 Huo Ke-Ke, Yu Lan-Lan, Chen Xin-Jie, Li Yu-Yang: A stable vector for high level expression and secretion of human interferon αA gene in yeast. Science in China, 36:557-567, 1993
6 沈綠萍,王二力,潘鐵城,戴培華,李載平,李育陽:B型肝炎病毒HbsAg 基因在酵母中GAL10啟動子控制下的表達,生物化學與生物物理學報,16(3):320-323,1984
7 Hui Pan, Wen-Xin Qin, Ke-Ke Huo, Da Fang Wan, Yu-Yang Li and Jian-ren Gu et.al.: Cloning, mapping, and characterization of a human homologue of the yeast longevity assurance gene LAG1, Genomics, 77(1-2): 58-64, 2001
8 Hu QD, Lu H, Huo K, Ying K, Mao Y, Li YY: A human homology of the yeast gene encoding tRNA 2'-phosphotransferase: cloning,,chareacterization and complementation analysis. Cell Mol Life Sci. 60(8):1725-32,2003
9 J Zhang, H. Yuan, T. Wen, F. Xu, Y.Di, K.Huo, Y-Y. Li: Cloning of the KcURA3 gene and development of a transformation system for Kluyveromyces cicerisporus. Applied Microbiology and Biotechnology, 2003
10 陳向嶺,袁漢英,何煒,胡翔華,呂紅,李育陽:通過同源重組構建酵母新型表達質粒 中國科學 C輯 生命科學 35(1):37-43,2005
11 Jian-Ping Liu, Nan-Song Liu, Han-Ying Yuan, Qian Guo, Hong Lu, Yu-Yang Li. Human Homologue of Seta Binding Protein 1 Interacts with Cathepsin B and Participates in TNF-Induced Apoptosis in Ovarian Cancer Cells. Molecular and Cellular Biochemistry 292(1-2): 189-195, 2006