周炳升

周炳升,1965年1月出生於山東榮成,責任研究員,博士研究生導師,環境毒理組組長。畢業於武漢大學生物系,獲學士(1986),碩士學位(1989)。於香港城市大學獲理學博士學位(2000)。於加拿大McMaster大學生物系做博士後研究,隨後在香港城市大學海岸污染與環境保護研究中心工作。2005年1月入選中國科學院“百人計畫”。研究方向為環境毒理學,特別是有機污染物對水生生物作用的分子機制、危險評價、健康危害及生態毒理學效應。現擔任《科學通報》(Chinese Science Bulletin) 、《環境化學》、《生態毒理學報》,,編委,是中國化學會環境化學專業委員會委員。獲得2011年度中國科學院優秀研究生導師獎和2012年度中國科學院朱李月華優秀教師獎。

基本信息

姓 名:  周炳升

性 別:  男

職 稱:  研究員

學 歷:  博士

研究方向

環境毒理學

專家類別

百人

代表論著

1. Wang Q, Chen Q, Zhou P, Li W, Wang J, Huang C, Wang X, Lin K, Zhou B*. Bioconcentration and metabolism of BDE-209 in the presence of titanium dioxide nanoparticles and impact on the thyroid endocrine system and neuronal development in zebrafish larvae. Nanotoxicology (in press).

2. Guo Y, Zhou B*, 2013. Thyroid endocrine system disruption by pentachlorophenol: an in vitro and in vivo assay. Aquatic Toxicology

3. Wang X, Yang Y, Zhang L, Ma Y, Han J, Yang L, Zhou B*, 2013. Endocrine disruption by di-(2-ethylhexyl)-phthalate in Chinese rare minnow (Gobiocypris rarus). Environmental Toxicology & Chemistry

4. Chen L, Huang Y, Huang C, Hu B, Hu C, Zhou B*, 2013. Acute exposure to DE-71 causes alterations in visual behavior in zebrafish larvae. Environmental Toxicology & Chemistry

5. Wang Q, Liang K, Liu J, Yang L, Guo Y, Liu C*, Zhou B*, 2013. Exposure of zebrafish embryos/larvae to TDCPP alters concentrations of thyroid hormones and transcriptions of genes involved in the hypothalamic-pituitary-thyroid axis. Aquatic Toxicolo

6. Chen L, Huang C, Hu C, Ke Y, Yang L, Zhou B*, 2012. Acute exposure to DE-71: Effects on locomotor behavior and developmental neurotoxicity in zebrafish larvae. Environmental Toxicology & Chemistry

7. Chen L, Yu K, Huang C, Yu L, Zhu B, PKS Lam, JCW Lam*, Zhou B*, 2012. Prenatal transfer of polybrominated diphenyl ethers (PBDEs) results in developmental neurotoxicity in zebrafish larvae. Environmental Science & Technology

8. Ma Y, Han J, Guo Y, Lam PKS, Wu RSS, Giesy JP, Zhang X, Zhou B*, 2012. Disruption of endocrine function in in vitro H295R cell-based and in in vivo assay in zebrafish by 2,4-dichlorophenol. Aquatic Toxicology

9. Chen Q, Yu L, Yang L, Zhou B*, 2012. Bioconcentration and metabolism of decabromodiphenyl ether (BDE-209) result in thyroid endocrine disruption in zebrafish larvae. Aquatic Toxicology

10. Chen L, Hu C, Huang C, Wang Q, Wang X, Yang L, Zhou B*, 2012. Alterations in retinoid status after long-term exposure to PBDEs in zebrafish (Danio rerio). Aquatic Toxicology

11. Ma Y, Han J, Guo Y, Lam PKS, Wu RSS, Giesy JP, Zhang X, Zhou B*, 2011. Modulation of steroidogenic gene expression and hormone synthesis in H295R cells exposed to PCP and TCP. Toxicology

12. Yu L, Lam JCW, Guo Y, Wu RSS, Lam* PKS, Zhou B*, 2011. Parental transfer of PBDEs and thyroid endocrine disruption in zebrafish. Environmental Science & Technology

13. Liu C, Zhang X, Deng J, Hecker M, AL-Khedhairy A, Giesy JP, Zhou B*, 2011. Effects of prochloraz or propylthiouracil on the cross-talk between the HPG, HPA and HPT Axes in zebrafish. Environmental Science & Technology

14. Liu C, Zhang X, Chang H, Jones P, Wiseman S, Naile J, Hecker M, Giesy JP, Zhou B*, 2010. Effects of fluorotelomer alcohol 8:2 FTOH on steroidogenesis in H295R cells: Targeting the cAMP signaling cascade. Toxicology & Applied Pharmacology

15. Shi X, Zhou B*, 2010. The role of Nrf2 and MAPK pathways in PFOS-induced oxidative stress in zebrafish embryos. Toxicological Sciences

16. Yu L, Deng J, Shi X, Liu C, Yu K, Zhou B*, 2010. Exposure to DE-71 alters thyroid hormone levels and gene transcription in the hypothalamic–pituitary–thyroid axis of zebrafish larvae. Aquatic Toxicology

17. Liu C, Deng J, Yu L, Ramesh M, Zhou B*, 2010. Endocrine disruption and reproductive impairment in zebrafish by exposure to 8:2 fluorotelomer alcohol. Aquatic Toxicology

18. Deng J, Liu C, Yu L, Zhou B*, 2010. Chronic exposure to environmental levels of tribromophenol impairs zebrafish reproduction. Toxicology & Applied Pharmacology

19. Shi X, Yeung LWY, Lam PKS, Wu RSS, Zhou B*, 2009. Protein Profiles in Zebrafish (Danio rerio) Embryos Exposed to PFOS. Toxicological Sciences

20. Deng J, Yu L, Liu C, Yu K, Shi X, Yeung L, Lam PKS, Wu RSS, Zhou B*, 2009. Hexabromocyclododecane-induced developmental toxicity and apoptosis in zebrafish embryos. Aquatic Toxicology

21. Liu C, Yu L, Deng J, Lam PKS, Wu RSS, Zhou B*, 2009. Waterborne exposure to fluorotelomer alcohol 6:2 FTOH alters plasma sex hormone and gene transcription in the hypothalamic–pituitary–gonadal (HPG) axis of zebrafish. Aquatic Toxicology

22. Shi X, Liu C, Wu G, Zhou B*, 2009. Waterborne exposure to PFOS causes disruption of the hypothalamus-pituitary- thyroid axis in zebrafish larvae. Chemosphere

23. Du Y, Shi X, Liu C, Yu K, Zhou B*, 2009. Chronic effects of waterborne PFOS exposure on growth, survival and hepatotoxicity in zebrafish: a partial life-cycle test. Chemosphere

24. Yu K, He Y, Yeung LWY, Lam PKS, Wu RSS, Zhou B*, 2008. DE-71-induced apoptosis involving intracellular calcium and the Bax-mitochondria-caspase protease pathway in human neuroblastoma cells in vitro. Toxicological Sciences

25. Shi X, Du Y, Lam PKS, Wu RSS, Zhou B*, 2008. Developmental toxicity and alteration of gene expression in zebrafish embryos exposed to PFOS. Toxicology & Applied Pharmacology

26. Liu C, Du Y, Zhou B*, 2007. Evaluation of estrogenic activities and mechanism of action of perfluorinated chemicals determined by vitellogenin induction in primary cultured tilapia hepatocytes. Aquatic Toxicology

27. Ding L, Murphy MB, He Y, Xu Y, Yeung LWY, Wang J, Zhou B*, Lam PKS, Wu RSS, Giesy JP, 2007. Effects of brominated flame retardants and brominated dioxins on steroidgenesis in H295R cells. Environmental Toxicology & Chemistry

28. Liu C, Yu K, Shi X, Wang J, Lam PKS, Wu RSS, Zhou B*, 2007. Induction of oxidative stress and apoptosis by PFOS and PFOA in primary cultured hepatocytes of freshwater tilapia (Oreochromis niloticus). Aquatic Toxicology

29. Zhou B*, Liu C, Wang J, Lam PKS, Wu RSS, 2006. Primary cultured cells as sensitive in vitro model for assessment of toxicants-comparison to hepatocytes and gill epithelia. Aquatic Toxicology

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