![韓東[國家納米科學中心研究員]](/img/5/0e0/nBnauM3X1UjM3UDO5ATO1ATN0UTMyITNykTO0EDMwAjMwUzLwkzLzQzLt92YucmbvRWdo5Cd0FmLwE2LvoDc0RHa.jpg "韓東[國家納米科學中心研究員]")
人物經歷
韓東，研究員，博士生導師。1998年在中國中醫研究院（現更名為中國中醫科學院）獲中西醫結合血液學臨床醫學碩士學位，2001年獲中西醫結合血液學基礎醫學博士學位。之後在清華大學物理系、香港浸會大學中醫藥學院、法國巴黎高等師範學院化學系從事博士後，訪問及高級訪問學者研究工作。2004年3月進入國家納米科學中心工作。現任國際臨床血液流變學會國際聯絡員，中國病理生理學會微循環專業委員會當選副秘書長，中國生物物理學會生物力與生物流變專業委員會委員、中國中西醫結合學會微循環專業委員會委員、中國病理生理學會休克專業委員會當選委員。
研究方向
納米生物醫學成像與表征，生物醫學工程，生物力藥理學。以原子力顯微鏡、環境掃描電鏡為平台，特色套用及發展納米成像、表征、操縱及微加工集成設備功能群，研究生物醫學關鍵問題；生物活體功能界面“微尺度構建－功能－力學偶聯”相關機制研究。
主要貢獻
1. Liang Shi, Shenggen Shi, Jing Li, Quanmei Sun, Peipei Chen, Long Chen and Dong Han*.AFM and fluorescence imaging of nanomechanical response in periodontal ligament cells. Front. Biosci. 2010, Online.
2．Long Chen, Weiguo Chu, Yonggang Xu, Peipei Chen, Fang Lao, Quanmei Sun, Xizeng Feng and Dong Han*. Time-series investigation of fused vesicles in microvessel endothelial cells with atomic force microscopy. Microsc. Res. Techniq. 2010, 73, 152－159.
3. Liping Heng, Dongliang Tian, Long Chen, Junxin Su, Jin Zhai*, Dong Han* and Lei Jiang. Local photoelectric conversion properties of the titanyl-phthalocyanine (TiOPc) coated aligned ZnO nanorodsw. Chem Comm. 2010,46,1162.
4. Li Chen, Mingjie Liu, Hao Bai, Peipei Chen, Fan Xia, Dong Han* and Lei Jiang*.Antiplatelet and thermally responsive poly(N-isopropylacrylamide) surface by with nanoscale topography. J. Am. Chem. Soc. 2009, 131, 10467-10472 (Article).
5. Honglei Fan, Peipei Chen, Ruomei Qi, Jin Zhai, Jingxia Wang, Long Chen, Li Chen, Quanmei Sun, Yanlin Song, Dong Han* and Lei Jiang*. Largely improve blood-compatibility by microscopic multi-scale design of surface architectures. Small. 2009, 5, 2144-2148 (Highlighted by Nature Nanotechnology).
6. Fang Lao, Long Chen, Wei Li, Cuicui Ge, Ying Qu, Quanmei Sun, Yuliang Zhao, Dong Han* and Chunying Chen*.Fullerene nanoparticles selectively enter oxidation-damaged cerebral microvessel endothelial cells and inhibit JNK-related apoptosis. ACS NANO. 2009，3，3358-3368 (Article).
7．Peipei Chen, Hongtao Dong, Long Chen, Quanmei Sun and Dong Han*. The application of atomic force microscopy on living samples, from cells to fresh tissues. Chinese Sci.Bull. 2009, 54, 2410-2415 (Review).
8．Youdong Mao, Quanmei Sun, Xiufeng Wang, Qi Ouyang, Li Han, Lei Jiang* and Dong Han*. In vivo nanomechanical imaging of blood-vessel tissues directly in living mammals using atomic force microscopy. Appl. Phys. Lett. 2009，95，013704.
9．Peipei Chen, Long Chen, Dong Han*, Jin Zhai, Yongmei Zheng and Lei Jiang*. Wetting behavior at micro-/nanoscales: direct imaging of a microscopic water/air/solid three-phase interface. Small. 2009, 5, 908-912 (Inside Cover Picture).
10. Guanglu Ge, Dong Han*, Danying Lin, Weiguo Chu, Yunxu Sun, Lei Jiang, Wanyun Ma and Chen Wang. MAC mode atomic force microscopy studies of living samples, ranging from cells to fresh tissue. Ultramicroscopy. 2007, 107, 299-307.
11. Wanyun Ma, Yunxu Sun, Dong Han *, Weiguo Chu, Danying Lin and Dieyan Chen. Cytoskeletal response of microvessel endothelial cells to an applied stress force at the submicrometer scale studied by atomic force microscopy. Microsc. Res. Techniq. 2006, 69, 784-793.
國家標準
金屬納米粒子生物效應的環境掃描電子顯微鏡檢測方法通則。第一起草人。
納米粒子生物效應研究中活體生物樣本的磁驅動輕敲模式原子力顯微鏡檢測方法通則。第一起草人。
獲獎記錄
2002年獲國際生物流變學會頒發的第一屆“Chien-Fung Award”，獎勵1名有突出成績的中國青年生物力學工作者。2008年獲日本顯微鏡學會頒發的年度生物醫學論文獎。
