![王昊陽[博士]](/img/1/7ed/nBnauM3XygTN2AjN4ADM3gTNwUTMxYzM2ADN0QTNwAzMwIzLwAzLxMzLt92YucmbvRWdo5Cd0FmLwE2LvoDc0RHa.jpg "王昊陽[博士]")
個人簡歷
1996/09–2000/06，中國藥科大學，藥學院，藥物分析專業，本科
2000/09–2003/06，中國藥科大學與上海有機化學研究所聯合培養，碩士
2003/09–2006/06，中國科學院上海有機化學研究所，博士
2006/07–2008/07，德國奧爾登堡大學，化學系，博士後
2008/09–2017/02，中國科學院上海有機化學研究所，副研究員
2017/03–至今，中國科學院上海有機化學研究所，公共技術服務中心質譜組，課題組長
研究方向
主要從事有機質譜學研究，致力於開發質譜學新技術解決有機化學中有挑戰的難題，並基於有機化學基本理論發展新的質譜學方法。在新型質譜離子源研發，反應機理與氣相化學研究，食品安全和藥物分析的質譜快檢技術開發等方面取得了一些科研成果。
學術成就
近年代表性科研論文
1. Meng-XiWu,Hao-YangWang*,Jun-TingZhang,Yin-LongGuo*.MultifunctionalCarbonFiberIonizationMassSpectrometry,Anal.Chem.2016,88(19),9547−9553.
2. Jun-TingZhang,Hao-YangWang*,XiangZhang,FangZhang,Yin-LongGuo*.Studyofshort-livedandearlyreactionintermediatesinorganocatalyticasymmetricaminationreactionsbyion-mobilitymassspectrometry.Catal.Sci.Technol.2016,6,6637–6643.
3. QilunLiu,ZheliangYuan,Hao-YangWang*,YangLi,YichenWu,TaoXu,XuebingLeng,PinhongChen,Yin-longGuo,ZhenyangLin*,GuoshengLiu*.AbnormalMesoionicCarbeneSilverComplex:Synthesis,ReactivityandMechanisticInsightonOxidativeFluorination.ACSCatalysis,2015,5(11),6732–6737.
4. ZheliangYuan,Hao-YangWang,XinMu,PinhongChen,Yin-longGuo,GuoshengLiu*.HighlySelectivePd-CatalyzedIntermolecularFluorosulfonylationofStyrenes.J.Am.Chem.Soc.2015,137(7),2468–2471.
5. Xiao-PanLiu,Hao-YangWang*,Jun-TingZhang,Meng-XiWu,Wan-ShuQi,HuiZhu,Yin-LongGuo*.DirectandConvenientMassSpectrometrySamplingwithAmbientFlameIonization.ScientificReports,2015,5,16893.
6. Hao-YangWang*,Jun-TingZhang,Shu-ShengZhang,Yin-LongGuo*.Theremarkableroleofsolventinreactionmechanismstudiesbyelectrospraymassspectrometry.Org.Chem.Front.,2015,2,990–994.
7. Hao-YangWang*,Jun-TingZhang,Shi-HaoSun,Shu-ShengZhang,FangZhang,HuiZhu,Yin-LongGuo*.StudyontheAcceleratedGutknechtSelf-CyclocondensationofAmino-sugarsatAtmosphericPressureChemicalIonizationCondition.RSCAdvances,2015,5,105079–105083.
8. YouaiQiu,JingZhou,JunzhaoLi,ChunlingFu,Yin-longGuo,HaoyangWang*,ShengmingMa*.AsymmetricConstructionofSix-MemberedRingsbyCyclizationofAlleneswithDinuclearGoldCatalysis.Chem.Eur.J.2015,21(45):15939–15943.
9. Jun-TingZhang,Hao-YangWang*,WeiZhu,Ting-TingCai,Yin-LongGuo*.Solvent-assistedElectrosprayIonizationforDirectAnalysisofVariousCompounds(complex)fromLow/non-polarSolventsandEluents.Anal.Chem.2014,86(18),8937–8942.
10. HaoyangWang*,ZhixiongZhao,YinlongGuo*.ChemicalandbiochemicalapplicationsofMALDITOF-MSbasedonanalyzingthesmallorganiccompounds.in:ApplicationsofMALDI-TOFSpectroscopy.ZongweiCai,ShuyingLiu(Eds.)Top.Curr.Chem.2013,331,165–192.
11. Hao-YangWang*,YingGao,FangZhang,Chong-TianYu,ChuXu,Yin-LongGuo*.Massspectrometricstudyofthegas-phasedifluorocarbeneexpulsionofpolyfluorophenylcationsviaF-atommigration.J.Am.Soc.MassSpectrom.2013,24(12),1919–1926.
12. Hao-YangWang*,ZhangXiang,Guo-ShengLiu,Yin-LongGuo*.Studyofthegasphaseintramoleculararyltrifluoromethylationofphenyl(trifluoromethyl)iodoniumbyESI-MS/MS.J.Am.Soc.MassSpectrom.2013,24(5),761–767.
13. Hao-YangWang,Wai-LeungYim,Yin-LongGuo,JürgenO.Metzger*.ESI-MSstudiesandcalculationsonsecond-generationGrubbsandHoveyda-Grubbsrutheniumolefinmetathesiscatalysts.Organometallics2012,31(5),1627–1634.
14. XinMu,TaoWu,Hao-yangWang,Yin-longGuo,GuoshengLiu*.Palladium-catalyzedoxidativearyltrifluoromethylationofactivatedalkenesatroomtemperature.J.Am.Chem.Soc.2012,134(2),878–881.
15. Hao-YangWang,Wai-LeungYim,ThorstenKlüner,JürgenO.Metzger*.ESIMSstudiesandcalculationsonalkalimetaladductionsofRutheniumolefinmetathesiscatalystsandtheircatalyticactivityinmetathesisreactions.Chem.Eur.J.2009,15(41),10948-10959.
16. CesarA.Marquez,HaoyangWang,FrancescoFabbretti,JürgenO.Metzger*.Electron-transfer-catalyzeddimerizationoftrans-anethole:detectionofthedistonictetramethyleneradicalcationintermediatebyextractiveelectrosprayionizationmassspectrometry.J.Am.Chem.Soc.2008,130(51),17208-17209.
17. HaoyangWang,JürgenO.Metzger*.ESI-MSStudyonfirstgenerationRutheniumolefinmetathesiscatalystsinsolution:directdetectionofthecatalyticallyactive14-electronrutheniumintermediate.Organometallics.2008,27(12),2761-2766.
18. Hao-YangWang,QingHongTang,XiangZhang,Yin-LongGuo*,LongLu*.Usingtandemmassspectrometrytopredictchemicaltransformationsof2-pyrimidinyloxy-N-arylbenzylaminederivativesinsolution.J.Am.Soc.MassSpectrom.2006,17(2),253-263.
19. Hao-YangWang,XiangZhang,Yin-LongGuo*,LongLu*.Massspectrometricstudiesofthegasphaseretro-Michaeltypefragmentationreactionsof2-hydroxybenzyl-N-Pyrimidinylaminederivatives.J.Am.Soc.MassSpectrom.2005,16(10),1561-1573.
20. Hao-YangWang,Yin-LongGuo*,LongLu*.Studiesofrearrangementreactionsofprotonatedandlithiumcationized2-pyrimidinyloxy-N-arylbenzylaminederivativesbyMALDI-FTICRMS.J.Am.Soc.MassSpectrom.2004,15(12),1820-1832.
王昊陽博士會議報告國際科技會議的口頭報告
1.ESI-MSStudyonFirstGenerationRutheniumOlefinMetathesisCatalystsinSolution.DGMS,Mar,2008,Giessen,Germany2.TandemMassSpectrometricStudyofReactiveIntermediatesinOrganicReactions.BCEIA,Dec,2009,Beijing,P.R.China.3.
3.MassSpectrometricStudyof“Fluorinedancing”.ThesixthnationalconferenceonEnvironmentchemistry.5thAOMSC&33rdCMSSAnnualConference.July,2014.Beijing,P.R.China
國內科技會議的口頭報告
1.質譜學研究快反應中瞬態活潑中間體，中國質譜學會第31屆年會，西安，2011年8月7日2.基於碳纖維的離子源的研製與開發，中國化學會第二屆全國質譜分析學術報告會，杭州，2015年10月18日
3.離子漂移質譜技術在有機反應機理研究中的套用，中國化學會第十八屆全國有機分析及生物分析學術研討會，上海，2015年4月17日
4.質譜學為有機化學研究提供新視野，中國科學院青年創新促進會2016年學術年會暨會員代表大會，成都，2016年11月17日
5.捕捉瞬息變幻-質譜學揭秘有機化學反應，中國化學會第十九屆全國有機分析及生物分析學術研討會，四川成都，2017年3月31日
所獲榮譽
2013年加入中科院青年創新促進會2015年加入中國共產黨，中國化學會有機分析專業委員會委員
2016年入選《分析測試學報》首屆青年編委，2017年課題組長
