王健[西南大學藥學院副教授]

王 健:理學博士,西南大學副教授,碩士生導師。

個人簡介:2012年7月畢業於西南大學,2010年9月至2011年9月獲國家留學基金委資助在美國University of Florida進行為期一年的公派學習。博士畢業論文被推薦為重慶市優秀學位論文。 研究方向:生化感測與生物藥物分析、癌症光熱治療 研究興趣:新型納米材料的在生物醫藥分析中的套用 核酸適配體的生化感測及癌症治療中的分析套用。

主持項目:

國家自然科學基金:金納米棒組裝體在超長程共振能量轉移中的生化分析套用研究

重慶市自然科學基金計畫項目:過渡金屬硫屬化物量子點的局域表面電漿共振及其生物醫學分析套用研究

中央高校基本科研業務費項目:金納米棒組裝體在生物醫藥可視化檢測中的套用

雲南大學合作開發橫向項目:銀納米三棱粒子項目合作研究

博士啟動基金:新型納米材料組裝體在藥物運輸及癌症治療中的分析套用研究

西南大學教改項目:藥學專業探究式實驗教學方法研究——以分析化學實驗課為例

代表性論文:

1. Wang, J.; Zhu, G.; You, M.; Song, E.; Shukoor, M. I.; Zhang, K.; Altman, M. O. D.; Chen, Y.; Zhu, Z.; Huang, C. Z.*; Tan, W.* Assembly of Aptamer Switch Probes and Photosensitizer on Gold Nanorods for Targeted Photothermal and Photodynamic Cancer Therapy. ACS Nano 2012, 6, 5070-5077.(IF= 12.033)

2. Wang, J.; You, M.; Zhu, G.; Shukoor, M. I.; Chen, Z.; Zhao, Z.; Altman, M. B.; Yuan, Q.; Zhu, Z.; Chen, Y.; Huang, C. Z.*; Tan, W.* Photosensitiser-Gold Nanorods Composite for Targeted Multimodal Therapy. Small 2013, 9, 3678-3684. (IF= 7.514)

3. Wang, J.; Wang, T. T.; Gao, P. F.; Huang, C. Z.* Biomolecules-conjugated nanomaterials for targeted drug delivery. J. Mater. Chem. B, 2014, 2(48), 8452-8465. (IF=6.626)

4. Wang, J.; Zhang, P.; Li, C. M.; Li, Y. F.; Huang, C. Z.* A Highly Selective and Colorimetric Assay of Lysine by Molecular-Driven Gold Nanorods Assembly. Biosens. Bioelectron. 2012, 34, 197-201. (IF=6.451)

5. Wang, J.; Li, Y. F.; Huang, C. Z.* Identification of Iodine-Induced Morphological Transformation of Gold Nanorods. J. Phys. Chem. C 2008, 112, 11691-11695. (IF=4.835)

6. Wang, J.; Li, Y. F.; Huang, C. Z.*; Wu, T. Rapid and Selective Detection of Cysteine Based on Its Induced Aggregates of Cetyltrimethylammonium Bromide Capped Gold Nanoparticles. Anal. Chim. Acta 2008, 626, 37-43. (IF=4.517)

7. Wang, J.; Sefah, K.; Altman, M. B.; Chen, T.; You, M.; Zhao, Z.; Huang, C. Z.*; Tan, W.* Aptamer-Conjugated Nanorods for Targeted Photothermal Therapy of Prostate Cancer Stem Cells. Chem. Asian J., 2013, 8, 2417-2422. (IF=3.935)

8. Wang, J.; Zhang, P.; Li, J. Y.; Chen, L. Q.; Huang, C. Z.; Li, Y. F.* Adenosine-Aptamer Recognition-Induced Assembly of Gold Nanorods and a Highly Sensitive Plasmon Resonance Coupling Assay of Adenosine in the Brain of Model SD Rat. Analyst 2010, 135, 2826-2831. (IF=3.906)

9. Wang, J.; Zhang, Q.; De Liu, Z.; Huang, C. Z.* Calf thymus DNA-stabilized Polythiophene Fluorescence Probe for Label-free Detection of Spermine. Analyst 2012, 137, 5565-5570. (IF=3.906)

10. Wang, J.; Zhang, Q.; Tan, K. J.; Long, Y. F.; Ling, J.; Huang, C. Z.* Observable Temperature-Dependent Compaction-Decompaction of Cationic Polythiophene in the Presence of Iodide. J. Phys. Chem. B 2011, 115, 1693-1697. (IF=3.377)

11. Wang, J.; Gao, P. F.; Yang, X. X.; Wang, T. T.; Wang, J.*; Huang, C. Z.* Real-time imaging of intracellular drug release from mesoporous silica nanoparticles based on fluorescence resonance energy transfer. J. Mater. Chem. B 2014, 2, 4379-4386(IF=6.626).

12. Yang, H.; Liu, Y.; Gao, P. F.; Wang, J.*; Huang, C. Z.* A dark-field light scattering platform for real-time monitoring of the erosion of microparticles by Co2+. Analyst 2014, 139, 2783-2787. (IF=3.906)

13. Huang, J. T.; Zeng, Q. L.; Yang, X. X.; Wang, J.* A simple green route to prepare stable silver nanoparticles with pear juice and a new selective colorimetric method of cysteine. Analyst 2013, 138, 5296-5302. (IF=3.906)

14. Du, Y. Q.; Gao, P. F.; Wang, W.; Wang, T. T.; Chang, Y.; Wang, J.*; Huang, C. Z.* A simple rapid detection method of DNA based on ligation-mediated real-time fluorescence PCR. Analyst 2013, 138, 5745-5750. (IF=3.906)

15. Du, Y. Q.; Yang, X. X.; Li, W. L.; Wang, J.*; Huang, C. Z.*, A cancer-targeted drug delivery system developed with gold nanoparticles mediated DNA-doxorubicin conjugates. RSC Adv. 2014. (IF=3.708)

16. Chen, B. B.; Liu, H.; Huang, C. Z.; Ling J.; Wang, J.* .Rapid and convenient synthesis of stable silver nanoparticles with kiwi juice and its novel application for detecting protease K. New J Chem. 2015, in press. (IF=3.159)

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