![張小虎[蘇州大學特聘教授]](/img/3/d61/nBnauM3X3MzNwATNwcDO2kTO0UTMyITNykTO0EDMwAjMwUzL3gzLwEzLt92YucmbvRWdo5Cd0FmLzE2LvoDc0RHa.jpg "張小虎[蘇州大學特聘教授]")
個人履歷
學歷背景
1986.9-1990.6：北京大學，理學學士
1992.9-1997.11：Rutgers University，美國新澤西州立大學，博士
工作經歷
1990.8-1992.7：內蒙古金屬材料研究所，工程師
1998.3-1999.6：Chromagen Inc., San Diego, CA, USA. 研究員
1999.6-2000.10：Stratagene，an Agilent company，研究員，項目經理
2000.10-2008.2：Neurocrine Biosciences，資深研究員
2008.3-2012.4：BioDuro，a PPD company,北京，總監，資深總監，執行總監
2012.4-至今：蘇州大學藥學院，特聘教授
研究方向
（1）靶向中樞神經系統重大疾病的藥物研發：以帕金森氏病、抑鬱症、藥物成癮為靶向，尋找和發現新型小分子藥物。
（2）新型抗腫瘤藥物的研發：專注於胚胎通路（刺蝟通路拮抗劑，豪豬蛋白拮抗劑等）的候選藥物研發。
主要科研支持
國家自然科學基金項目：腺苷受體拮抗劑抗帕金森綜合症的研究（2013-2016）
國家自然科學基金項目：刺蝟通路拮抗劑抗腫瘤藥物的研發（2015-2018）
蘇州大學科研啟動基金等
研究成果
1. Preparation of aminopyridazine derivatives and analogs for use as histamine H4 receptor modulators. Cai, Hui; Chavez, Frank; Dunford, Paul J.; Greenspan, Andrew J.; Meduna, Steven P.; Quiroz, Jorge A.; Savall, Brad M.; Tays, Kevin L.; Thurmond, Robin L.; Wei, Jianmei; Wolin, Ronald L.; Zhang, Xiaohu (with J&J). World Patent
2. Substituted pyrimidines as adenosine receptor antagonists. Chen, Y.; Moorjani, M.; Slee, D.; Tellow, J.; Zhang, X. World Patent,
3. Phenoxy-substituted pyrimidines as adenosine receptor antagonists. Slee, D.; Zhang, X.; Rueter, J. K.; Lin, E.; Crespo, M. I.; Castro, J. World Patent,
4. Substituted Pyrimidines as adenosine receptor antagonists. Slee, D.; Lanier, M.; Vong, B.; Chen, Y.; Zhang, X.; Lin, E.; Moorjani, M., Castro, J. World Patent,
5. Preparation of pyrazolo [1, 5-a] pyrimidines as corticotrophin-releasing factor (CRF) receptor antagonists. Lanier, M.; Luo, Z.; Moorjani, M.; Tellew, J.; Williams, J.; Zhang, X. World Patent,
6. Preparation of pyrazolopyrimidines as CRF receptor antagonists. Luo, Z.; Slee, D.; Tellew, J.; Williams, J.; Zhang, X. World Patent
7. Preparation of pyrazolopyrimidines as CRF receptor antagonists. Luo, Z.; Slee, D.; Tellew, J.; Williams, J.; Zhang, X. World Patent,
8. Preparation of Peptides as Ligands of Melanocortin Receptors. Dyck, B. P.; Goodfellow, V.; Phillips, T.; Parker, J.; Zhang, X.; Chen, C.; Tran, J. A.; Pontillo, J.; Tucci, F. C. World Patent
9. Universal Allyl Linker for Solid-Phase Nucleic Acid Synthesis. Zhang, X.; Jones, R. A. United States Patent.
