何宏輝[清華大學副研究員]

何宏輝，清華大學副研究員， 從事光學成像方法及其在生物醫學套用研究。

個人資料

何宏輝，清華大學副研究員，碩士生導師， 從事光學成像方法及其在生物醫學套用研究。

工作經歷

2013/09至今，清華大學，深圳研究生院，講師，副研究員

2011/09—2013/09，清華大學，深圳研究生院，博士後

研究方向

主要從事光學成像方法及其在生物醫學套用方面的研究，具體研究領域包括偏振散射成像原理，偏振光與生物組織相互作用模型，偏振散射成像在癌變檢測方面的套用等。目前主持科技部國家重點研發計畫-重大科學儀器設備開發項目課題一項：顆粒物特異性表征和源識別的偏振光學模型算法與系統最佳化；國家自然科學基金青年基金項目一項：與樣品取向無關的偏振光散射多波長成像方法及套用研究；深圳市科技研發資金國際科技合作項目一項：偏振內窺及臨床套用研究。已結題中國博士後科學基金一項：上皮組織早期癌變的穆勒矩陣偏振光成像參數研究。以主要成員身份參與國家自然科學基金項目三項：國家自然科學基金國家重大科研儀器研製項目-模組化穆勒矩陣顯微鏡及其典型臨床套用演示；國家自然科學基金面上項目-偏振組織光學模型與偏振成像病理診斷方法研究；國家自然科學基金面上項目-癌變組織穆勒矩陣與現場診斷方法研究 。

個人作品

[1] Honghui He, Chao He, Jintao Chang, Donghong Lv, Jian Wu, Chaijie Duan, Qian Zhou, Nan Zeng, Yonghong He, and Hui Ma. “Monitoring microstructural variations of fresh skeletal muscle tissues byMueller matrix imaging”, Journal of Biophotonics, 1–10 (2016) / DOI 10.1002/jbio.201600008.

[2] Ye Wang, Honghui He, Jintao Chang, Chao He, Shaoxiong Liu, Migao Li, Nan Zeng, Jian Wu, and Hui Ma. “Mueller matrix microscope: a quantitative tool to facilitate detections and fibrosis scorings of liver cirrhosis and cancer tissues”, Journal of Biomedical Optics, 21(7): 071112, 2016.

[3] Jintao Chang, Honghui He, Ye Wang, Yi Huang, Xianpeng Li, Chao He, Ran Liao, Nan Zeng, Shaoxiong Liu, and Hui Ma. “Division of focal plane polarimeter-based3*4 Mueller matrix microscope: a potential tool for quick diagnosis of human carcinoma tissues”, Journal of Biomedical Optics, 21(5): 056002, 2016.

[4] Yang Dong, Honghui He, Chao He, Jialing Zhou, Nan Zeng, and Hui Ma. “Characterizing the effects of washing by different detergents on the wavelength-scale microstructures of silk samples using Mueller matrix polarimetry”, International Journal of Molecular Sciences, 17(8): 1301, 2016.

[5] Chao He, Honghui He, Xianpeng Li, Jintao Chang, Ye Wang, Shaoxiong Liu, Nan Zeng, Yonghong He, and Hui Ma. “Quantitatively differentiating microstructures of tissues by frequency distributions of Mueller matrix images”, Journal of Biomedical Optics, 20(10): 105009, 2015.

[6] Ye Wang, Honghui He, Jintao Chang, Nan Zeng, Shaoxiong Liu, Migao Li, and Hui Ma. “Differentiating characteristic microstructural features of cancerous tissues using Mueller matrix microscope”, Micron, 79: 8-15, 2015.

[7] Chao He, Honghui He, Jintao Chang, Yang Dong, Shaoxiong Liu, Nan Zeng, Yonghong He, and Hui Ma. “Characterizing microstructures of cancerous tissues using multispectral transformed Mueller matrix polarization parameters”, Biomedical Optics Express, 6(8): 2934-2945, 2015.

[8] Honghui He, Nan Zeng, Ran Liao, and Hui Ma. “Progresses of polarization imaging techniques and their applications in cancer detections”, Progress in Biochemistry and Biophysics, 52(5): 419-433, 2015.

[9] Honghui He, Minghao Sun, Nan Zeng, E Du, Shaoxiong Liu, Yihong Guo, Jian Wu, Yonghong He, and Hui Ma. “Mapping local orientation of aligned fibrous scatterers for cancerous tissues using backscattering Mueller matrix imaging”, Journal of Biomedical Optics, 19(10): 106007, 2014.

[10] Minghao Sun, Honghui He, Nan Zeng, E Du, Yihong Guo, Shaoxiong Liu, Jian Wu, Yonghong He, and Hui Ma. “Characterizing the microstructures of biological tissues using Mueller matrix and transformed polarization parameters”, Biomedical Optics Express, 5(12): 4223-4234, 2014.

[11] E Du, Honghui He, Nan Zeng, Minghao Sun, Yihong Guo, Jian Wu, Shaoxiong Liu, and Hui Ma. “Mueller matrix polarimetry for differentiating characteristic features of cancerous tissues”, Journal of Biomedical Optics, 19(7): 076013, 2014.

[12] Honghui He, Nan Zeng, E Du, Yihong Guo, Dongzhi Li, Ran Liao, Yonghong He, and Hui Ma. “Two-dimensional and surface backscattering Mueller matrices of anisotropic sphere-cylinder scattering media: a quantitative study of influence from fibrous scatterers”, Journal of Biomedical Optics, 18(4): 046002, 2013.

[13] Honghui He, Nan Zeng, Dongzhi Li, Ran Liao, and Hui Ma. “Quantitative Mueller matrix polarimetry techniques for biological tissues”, Journal of Innovative Optical Health Sciences, 5(3): 1250017, 2012.

[14] Honghui He, Nan Zeng, Wei Li, Tianliang Yun, Ran Liao, Yonghong He, and Hui Ma. “Two-dimensional backscattering Mueller matrix of sphere-cylinder scattering medium”, Optics Letters, 35(14): 2323-2325, 2010.

[15] Honghui He, Nan Zeng, Ran Liao, Tianliang Yun, Wei Li, Yonghong He, and Hui Ma. “Application of sphere-cylinder scattering model to skeletal muscle”, Optics Express, 18(14): 15104-15112, 2010.

【學術兼職】中國光學學會第二屆生物醫學光子學專業委員會青年委員；國際光學工程學會SPIE會員；美國光學學會OSA會員。