![齊潔[中國海洋大學海洋生命學院教授]](/img/8/8a4/nBnauM3XycjM3QTN4cTO2kTO0UTMyITNykTO0EDMwAjMwUzL3kzLyIzLt92YucmbvRWdo5Cd0FmLxE2LvoDc0RHa.jpg "齊潔[中國海洋大學海洋生命學院教授]")
人物經歷
2014-至今 中國海洋大學 教授；
2009-2010 美國The Scripps Research Institute 博士後；
2007 -2009 美國哈佛醫學院 博士後；
2006 -2014 中國海洋大學 副教授；
2002 -2005 中國海洋大學 講師；
1999 -2002 山東農業大學 博士 。
研究方向
魚類發育和遺傳育種。
1、 鮃鰈魚在發育的過程中有一個特殊的變態過程，由兩隻眼睛在頭骨中線的兩側轉到同一側，形成有眼側和盲側，本課題組對這個變態過程的調控機理進行研究；
2、 海水魚類的轉基因長期以來一直是海水魚類基因功能研究的重點，本課題組通過用顯微注射技術、精子介導等轉基因方法進行嘗試，以期建立海水魚類轉基因體系。
主要貢獻
課題
1、 主持國家自然科學基金 “ miR-430和miR-92對鮃鰈胚胎髮育早期克氏泡中胞液流的網路調控”（課題號31372511，2014-2017年，在研）；
2、 參加十二五“863” 課題“海水養殖生物重要功能基因的發掘與研究”（課題號2012AA10A401，2012年-2015年，在研）；
3、 主持國家自然科學基金“鮃鰈胚胎髮育過程中克氏泡纖毛及其擺動形成的nodal胞液流和Nodal信號途徑與體態不對稱之間的關係”（課題號31072204，2011-2013年，已結題）；
4、 主持國家自然科學基金“MRC19基因在鮃鰈魚體態偏轉中的作用” （課題號30600455，2007-2009年，已結題)；
5、 主持山東省優秀青年科學家獎勵基金 “石鰈變態相關基因的篩選與克隆（課題號2006BS07006，已結題）”；
6、 子課題負責人承擔“863” 課題 “名貴海水魚類苗種規模化繁育（課題號2006AA10A 414，已結題）”；
7、 子課題負責人承擔“973”項目“重要養殖魚類品種改良的遺傳和發育基礎研究”（課題號2004CB117402，已結題） 。
主要論文
1、 Huayu Song,Yan He,Liman Ma,Xiaosu Zhou,Xiumei Liu, Jie Qi, Quanqi Zhang. Characterisation of kisspeptin system genes in an ovoviviparous teleost: Sebastes schlegeli. Gen Comp Endocrinol.2014 Jun 20. pii: S0016-6480(14)00243-3. doi: 10.1016/j.ygcen.2014.06.010. (Corresponding author)
2、 J Qi,X D Liu,J X Liu,H Y Yu,W J Wang,Z G Wang,Q Q Zhang. Molecular characterization of heat shock protein 70 (HSP 70) promoter in Japanese flounder (Paralichthys olivaceus), and the association of Pohsp70 SNPs with heat-resistant trait. Fish Shellfish Immunol.2014 Aug;39(2):503-11. doi: 10.1016/j.fsi.2014.05.038.
3、 Nian Xin,Tiantian Liu,Haitao Zhao,Zhenwei Wang,Jinxiang Liu,Quanqi Zhang, Jie Qi. The impact of exogenous DNA on the structure of sperm of olive flounder (Paralichthys olivaceus). Anim Reprod Sci.2014 Jul 3. pii: S0378-4320(14)00201-2. doi: 10.1016/j.anireprosci.2014.06.029. (Corresponding author)
4、 Tomoyuki Sasaki,Shanshan Lian, Jie Qi,Peter E Bayliss,Christopher E Carr,Jennifer L Johnson,Sujay Guha,Patrick Kobler,Sergio D Catz,Matthew Gill,Kailiang Jia,Daniel J Klionsky,Shuji Kishi Aberrant autolysosomal regulation is linked to the induction of embryonic senescence: differential roles of Beclin 1 and p53 in vertebrate Spns1 deficiency. PLoS Genetics 06/2014; 10(6):e1004409.
5、 Liu C, Xin N, Zhai Y, Jiang L, Zhai J, Zhang Q, Qi J. Reference Gene Selection for Quantitative Real-Time RT-PCR Normalization in the Half-Smooth Tongue Sole (Cynoglossus semilaevis) at Different Developmental Stages, in Various Tissue Types and on Exposure to Chemicals. PLoS One. 2014 Mar 25;9(3):e91715. doi: 10.1371/journal.pone. 0091715. eCollection 2014. (Corresponding author)
6、 Ma L, Wang W, Yang X, Jiang J, Song H, Jiang H, Zhang Q, Qi J. Characterization of the Dmrt1 gene in the black rockfish Sebastes schlegeli revealed a remarkable sex-dimorphic expression. Fish Physiol Biochem. 2014 Feb 25. (Corresponding author)
7、 Xia G, Xin N, Liu W, Yao H, Hou Y, Qi J. Inhibitory effect of Lycium barbarum polysaccharides on cell apoptosis and senescence is potentially mediated by the p53 signaling pathway. Mol Med Rep. 2014 Apr; 9(4):1237-41. doi: 10.3892/mmr.2014.1964. Epub 2014 Feb 19. (Corresponding author)
8、 Liman M, Wenji W, Conghui L, Haiyang Y, Zhigang W, Xubo W, Jie Q, Quanqi Z. Selection of reference genes for reverse transcription quantitative real-time PCR normalization in black rockfish (Sebastes schlegeli). Mar Genomics. 2013 Sep;11:67-73. doi: 10.1016/j.margen. 2013.08.002. Epub 2013 Sep 3.
9、 Eriko Koshimizu, Shintaro Imamura, Jie Qi, Jamal Toure, Delgado M. Valdez Jr.,Christopher E. Carr, Jun-ichi Hanai, Shuji Kishi. Embryonic Senescence and Laminopathies in a Progeroid Zebrafish Model, PLOS ONE. 2011，6(3): e17688
10、 Chen Yanjie, Zhang Quanqi, Qi Jie, Wang xubo, Sun Yeying, Zhong Qiwang, Li Shou, Li Chunmei, Cloing CK-M1gene and stage-specific expression during metamorphosis of Janpanese flounder Paralichtys olivaceus, Chinese Journal of Oceanology and Limnology. 2010, 28(3):558- 564. (Corresponding author)
11、 Fan Y, Li S, Qi J, Zeng L, Zhing Q, Zhang Q. Cloning and characterization of type II Interleukin-1 receptor cDNA from Japanese flounder (Paralichthys olivaceus). Comp Biochem Physiol B Biochem Mol Biol. 2010, 157(1):59-65.
12、 Sun Y, Yu H, Zhang Q, Qi J, Zhong Q, Chen Y, Li C. Molecular characterization and expression pattern of two zona pellucida genes in half-smooth tongue sole (Cynoglossus semilaevis). Comp Biochem Physiol B Biochem Mol Biol. 2010, 155(3):316-21.
13、 Sun Y, Zhang Q, Qi J, Chen Y, Zhong Q, Li C, Yu Y, Li S, Wang Z. Identification of differential genes in the oveary relative to the testis and their expression patterns in half-smooth tongue sole (Cynoglossus semilaevis) J Genet Genomics. 2010, 37(2):137-45.
14、 Li Shuo, Qi Jie, Wang Zhigang, Fan Yuding, Li Chunmei, Liu Zhipeng, Zhang Quanqi. Molecular cloning and expression analysis of fibrinogen β gene from Japanese flounder (Paralichthys olivaceus). Acta Scientiarum Naturalium Uniersitatis Sunyatseni. 2009,48: 89-94.
15、 Xu J, Zhang Q, Xu X, Wang Z, Qi J. Intragenomic variablity and pseudogenes of ribosomal DNA in stone flounder (Kareius biocoloratus). Mol Phylogenet Evol. 2009, 52(1):157-66.
16、 WANG Xubo, ZHANG Quanqi, CHEN Yanjie, QI Jie, WANG Zhigang, WANG Xinglian, Cytogenetic characterization of olive flounder Paralichthys olivaceus: DNA content, karyotype, AgNORs and location of major ribosomal genes. Acta Oceanologica Sinica, 2009, 28(4): 72-77.
17、 Chunmei Li, Quanqi Zhang, Jie Qi, Zhigang Wang. Summary of studies on major histocompatibility complex genes in fish. Transactions of Oceanology and Limnology. 2009,4: 39-50.
18、 Yanjie Chen, Quanqi Zhang, Jie Qi, Yeying Sun, Qiwang Zhong, Xubo Wang, Zhigang Wang, Shuo Li, Chunmei Li, Screening of eye-position related genes with DD-RT-PCR and RA in the hybrids between Japanese flounder Paralichthys olivaceus and stone flounder Kareius bicoloratus. Chinese Journal of Oceanology Limnology, 2009, 27 (1):92-99.
19、 Shuji Kishi, Peter E. Bayliss, Junzo Uchiyama, Eriko Koshimizu, Jie Qi, Purushothama Nanjappa, Shintaro Imamura, Asiful Islam, Donna Neuberg, Adam Amsterdam, and Thomas M. Roberts. The Identification of Zebrafish Mutants Showing Alterations in Senescence-Associated Biomarkers. PLOS Genetics. 2008, 4(8): 1-18.
