人物經歷
•2003—至今，山東大學，化學與化工學院，有機化學博士生導師；
•2001/9—至今，山東大學，化學與化工學院，教授；
•1997/9—2001/9，山東大學，化學院，副教授；
•1995/9—1997/9，山東大學，化學與環境學院，講師。
•1992/9—1995/8，中國科學院蘭州化學物理研究所，有機化學，博士，導師：金道森，童林薈；
•1989/9—1992/7，山東大學，有機化學，碩士，導師：黃慧琴；
•1985/9—1989/7，山東師範大學，化學，學士。
主講課程
•有機化學
•生物有機化學
•有機合成化學
•綜合化學實驗
研究方向
主要研究領域和興趣包括：有機合成; 藥物合成; 有機超分子化學; 功能分子的設計與合成; 功能新材料的設計與合成等。
功能分子的設計與合成
主要研究、設計、合成具有套用背景的功能分子，如藥物、香料、甜味分子、染料等等。
有機超分子化學
重點研究功能化有機超分子聚集體、超微環境的設計合成與性能；
非常重視功能性超微環境中的“酶”模擬反應，智慧型材料的設計合成等。
相對於以共價鍵為基礎，以分子為研究對象的傳統分子化學(molecular chemistry)而言，以多種弱相互作用力(或稱次級鍵)為基礎，以2個以上分子通過這種弱相互作用高層次組裝為研究對象的化學，可定義為“超越分子概念的化學”，也稱為超分子化學(supermolecular chemistry)。
與原子間由化學鍵作用而形成分子的分子化學不同，超分子化學是研究分子間相互作用締結而形成複雜有序且具有特定功能的分子聚集體的科學，這種分子聚集體簡稱超分子。換言之，超分子化學是研究通過非共價鍵作用形成功能體系的科學。
超分子作用是一種具有分子識別能力的分子間相互作用，通過對分子間相互作用的精確調控，超分子化學逐漸發展成為一門新興的分子信息化學，它包括在分子水平和結構特徵上的信息存儲，以及通過特異性相互作用的分子識別過程，實現在超分子尺寸上的修正、傳輸和處理。它是化學和多門學科的交叉領域，它不僅與物理學、材料科學、信息科學、環境科學等相互滲透形成了超分子科學，而更具有重要理論意義和潛在前景的是在生命科學中的研究和套用。例如生物體內小分子和大分子之間高度特異的識別在生命過程中的調控，生物體內的信息輸送( 電子轉移、能量傳遞、物質傳輸和化學轉換)和生物體中受體-底物相互作用等，其基本現象都離不開超分子化學範疇。
未來超分子體系的特徵應為“自適應化學，將在有機合成的“酶”模擬化、智慧型材料的構築等領域發揮關鍵作用。
功能新材料的設計與合成
主要研究、設計、合成具有套用背景的功能材料、複合製劑等，如有機光電材料、儲能材料、合成燃料、食品醫藥化妝品輔助材料，以及乳化劑、粘合劑、精細化工等。
主要貢獻
主要論著教材
1．《精編有機化學教程》(第二版)，國家“十一五”規劃教材
山東大學出版社，2009，08
2. 《精編有機化學教程》(第一版)
山東大學出版社，2003，07
科研項目
主要項目
作為主持人已完成或正在承擔的課題有20餘項，其中國家自然科學基金1項，國家及省部級課題7項。 近幾年的科研項目主要有： 1.乳酸環糊精衍生物醫用材料，2008-2011； 2.新型防堵塞塗層的開發，2009； 3.提取1-硝基蒽醌，2007-2009; 4.新型控環釋材料羥丁基環糊精衍生物，2006-2008； 5.葡萄糖基環糊精衍生物，2006-2007； 6.潤滑油添加劑結構分析；2006; 7.省科技廳:合成功能性大環分構築高性能藥用模型,1999-2003； 8.國家自然科學基金:構築楔筒狀空腔的主體分子新模型,2000-2002； 9.省科技廳:新型聚酸酐、聚酸酐微粒及納米微粒,2002-2003； 10.教育廳:智慧型提取劑：矽膠載改性環糊精衍生物省,2002-2003； 11.省科技廳:2,3,5-三甲氧基苯甲醛的合成,2003-2004； 12.省科技廳:強力醫藥控緩釋新材料：含低聚乳酸基團的環糊精衍生物的製備，2003-2004
科研成果
通訊作者論文
2016年
1. Xing Pengyao, Chen Hongzhong, Bai Linyi, Hao Aiyou*, Zhao Yanli*, Superstructure Formation and Topological Evolution Achieved by Self-Organization of a Highly Adaptive Dynamer, ACS Nano, 2016, 10(2): 2716-2727.
2. Xing Pengyao, Chen Hongzhong, Ma Mingfang, Xu Xingdong, Hao Aiyou*, Zhao Yanli, Light and cucurbit[7]uril complexation dual-responsiveness of a cyanostilbene-based self-assembled system, Nanoscale, 2016, 8(4): 1892-1896.
3. Xing Pengyao, Zhao Zhuo, Hao Aiyou*, Zhao Yanli*, Tailoring luminescence color conversion via affinitive co-assembly of glutamates appended with pyrene and naphthalene dicarboximide units, Chem Commun (Camb), 2016, 52(6): 1246-1249.
2015年
1. Chu Xiaoxiao, Xing Pengyao, Li Shangyang, Ma Mingfang, Hao Jingcheng, Hao Aiyou*, Dual-tuning multidimensional superstructures based on a T-shaped molecule: vesicle, helix, membraneand nanofiber-constructed gel†, RSC Advances, 2015, (5): 1969-1978.
2. Ma Mingfang, Gu Jinge, Yang Minmin, Li Zhaolou, Lu Zhuoqun, Zhang Yimeng, Xing Pengyao, Li Shangyang, Chu Xiaoxiao, Wang Yajie, Li Qi, Lin Minyan, Hao Aiyou*, Controllable self-assemblies of sodium benzoate in different solventenvironments†, RSC Advances, 2015, (5): 70178-70185.
3. Zhang Hanqiang, Huang Yihong, Huang Qitong, Wei Chan, Zhang Wuxiang, Yang Weize, Dong Peihui, Hao Aiyou*, Hu Shirong*, Self-assembly of graphitic carbon nitride nanosheets–carbon nanotube compositefor
electrochemical simultaneous determination of catechol and hydroquinone, Electrochimica Acta, 2015, 176: 28-35.
4. Li Shangyang, Zhang Lin, Wang Bo, Ma Mingfang, Xing Pengyao, Chu Xiaoxiao, Zhang Yimeng, Hao Aiyou*, An easy approach for constructing vesicles by using aromatic molecules with beta-cyclodextrin, Soft Matter, 2015, 11(9): 1767-1777.
5. Shirong Hu, Wuxiang Zhang, Jianzhong Zheng, Jiangu Shi, Zhongqiu Lin, Ling Zhong，Guixiang Cai, Chan Wei, Hanqiang Zhang, Aiyou Hao*, One step synthesis cadmium sulphide/reduced graphene oxide sandwiched film modified electrode for simultaneous electrochemical determination of hydroquinone, catechol and resorcinol, RSC Advances, 2015，-(5): 18615-18621.
6. Ma Mingfang, Shang Wenqing, Xing Pengyao, Li Shangyang, Chu Xiaoxiao, Hao Aiyou*, Liu Guangcun, Zhang Yimeng, A supramolecular vesicle of camptothecin for its water dispersion and controllable releasing, Carbohydrate Research, 2015, 402: 208-214.
7. Ma Mingfang, Xu Shengguang, Xing Pengyao, Li Shangyang, Chu Xiaoxiao, Hao Aiyou*, A multistimuli-responsive supramolecular vesicle constructed by cyclodextrins andtyrosine，Colloid and Polymer Science, 2015, 293: 891-900.
8. Zhang Hanqiang, Huang Yihong, Huang Qitong, Wei Chan, Zhang Wuxiang, Kang Lianping, Huang Zhouyi, Hu Shirong*, Hao Aiyou*, Fluorescent probes for “off–on” sensitive and selective detection ofmercury ions and
L-cysteine based on graphitic carbon nitrid nanosheets†, Journal of Materials Chemistry C, 2015, (3): 2093-2100.
2014年
1. Hou Yuehui, Li Shangyang, Sun Tao, Yang Jingshu, Xing Pengyao, Liu Wenqi, Hao Aiyou*, Organogels based on beta-cyclodextrin system with molecular recognition property, Journal of Inclusion Phenomena and Macrocyclic Chemistry, 2014, 80(3-4): 217-224.
2. Xing Pengyao, Chu Xiaoxiao, Ma Mingfang, Li Shangyang, Hao Aiyou*, Melamine as an effective supramolecular modifier and stabilizer in a nanotube-constituted supergel, Chem Asian J, 2014, 9(12): 3440-3450.
3. Chu Xiaoxiao, Xing Pengyao, Li Shangyang, Ma Mingfang, Hao Aiyou*, Inorganic salt-tuned multiple self-assemblies of supramolecular beta-cyclodextrin gel, Colloids and Surfaces A: Physicochemical and Engineering
Aspects, 2014, 461: 11-17.
4. Ma Mingfang, Sun Tao, Xing Pengyao, Li Zhaolou, Li Shangyang, Su Jie, Chu Xiaoxiao, Hao Aiyou*, A supramolecular curcumin vesicle and its application in controlling curcumin release，Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2014, 459: 157-165.
5. Ma Mingfang, Su Jie, Sheng Xiang, Su Fan, Li Shangyang, Xing Pengyao, Hao Aiyou*, Rapid regio- and enantioselectivities and kinetic resolution of DL-lysine by an effective supramolecular system in water, Journal of Molecular Liquids, 2014, 198: 1-4.
6. Xing Pengyao, Chu Xiaoxiao, Du Guangyan, Ma Mingfang, Li Shangyang, Hao Aiyou*, Utilizing dual responsive supramolecular gel to stabilize grapheme oxidein apolar solvents，Colloid and Polymer Science, 2014, 242: 3223-3231.
7. 馬明放，邢鵬遙，李尚洋，初曉曉，王波，郝愛友*，主客體超分子囊泡及其藥物載運性能研究，化學進展，2014，（08）：1317-1328。
8. Xing Pengyao, Chu Xiaoxiao, Li Shangyang, Ma Mingfang, Hao Aiyou*, Hybrid Gels Assembled from Fmoc-Amino Acid and Graphene Oxide with Controllable Properties, ChemPhysChem, 2014, 15(11): 2377-2385.
9. Li Zhaolou, Hao Aiyou*, Li Xiang, beta-Cyclodextrin supramolecular organogels induced by different carboxylic acids that exhibit diverse morphologies, Journal of Molecular Liquids, 2014, 196: 52-60.
10. Ma Mingfang, Guan Yun, Zhang Cai, Hao Jingcheng, Xing Pengyao, Su Jie, Li Shangyang, Chu Xiaoxiao, Hao Aiyou*, Stimulus-responsive supramolecular vesicles with effective anticancer activity prepared by cyclodextrin and ftorafur, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2014, 454: 38-45.
11. Li Zhaolou, Liu Wenqi, Hao Aiyou*, Gel-sol-gel evolution triggered by formic acid, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2014, 451: 25-32.
12. Hu Shirong, Huang Qitong, Lin Yi, Wei Chan, Zhang Hanqiang, Zhang Wuxiang, Guo Zhenbo, Bao Xiuxiu, Shi Jiangu, Hao Aiyou*, Reduced graphene oxide-carbon dots composite as an enhanced material for electrochemical determination of dopamine, Electrochimica Acta, 2014, 130: 805-809.
13. Hou Yuehui, Sun Tao, Xin Feifei, Xing Pengyao, Li Shangyang, Hao Aiyou*, Transformation from a heat-set organogel to a room-temperature organogel induced by alcohols, Journal of Inclusion Phenomena and Macrocyclic Chemistry, 2014, 79(1-2): 133-140.
14. Su Jie, Su Fan, Ma MingFang, Li Shangyang, Xing Pengyao, Hao Aiyou*, Selection of Amino Acids and the Biomimetic Synthesis of Amido Bond in the Presence of beta-CD, Synthetic Communications, 2014, 44(8): 1111-1121.
15. Li Shangyang, Xing Pengyao, Zhang Lin, Xin Feifei, Nie Jinhui, Wang Hailu, Ma Mingfang, Wu Yurong, Hao Aiyou*, Controllable self-assembly of an amphiphilic drug with beta-cyclodextrin and alpha-amylase, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2014, 445: 67-74.
16. Li Zhaolou, Hao Aiyou*, Hao Jingcheng, Formation of heat-triggered supramolecular organogel in which beta-cyclodextrin as sole gelator, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2014, 441: 8-15.
17. Xing Pengyao, Chu Xiaoxiao, Ma Mingfang, Li Shangyang, Zhang Yimeng, Hao Aiyou*, Self- assembly of folic acid/melamine complexes with hierarchy levels: from membranes to porous spherulites and networks, RSC
Advances, 2014, 4(69): 36633-36639.
18. Xing Pengyao, Chu Xiaoxiao, Ma Mingfang, Li Shangyang, Hao Aiyou*, Supramolecular gel from folic acid with multiple responsiveness, rapid self-recovery and orthogonal self-assemblies, Physical Chemistry Chemical
Physics, 2014, 16(18): 8346-8359.
19. Ma Mingfang, Xing Pengyao, Xu Shengguang, Li Shangyang, Chu Xiaoxiao, Hao Aiyou*, Reversible pH-responsive helical nanoribbons formed using camptothecin, RSC Advances, 2014, 4(80): 42372-42375.
20. 楊旭，郝愛友*，馮維春，疊氮化鈉的水相合成方法及其廢液處理，套用化工，2014，（06）：1156-1158+1164。
2013年
1. Li Shangyang, Xing Pengyao, Hou Yuehui, Yang Jingshu, Yang Xuezhi, Wang Bo, Hao Aiyou*, Formation of a sheet-like hydrogel from vesicles via precipitates based on an ionic liquid-based surfactant and beta-cyclodextrin, Journal of Molecular Liquids, 2013, 188: 74-80.
2. Li Shangyang, Sun Tao, Yang Xuezhi, Wang Bo, Xing Pengyao, Hou Yuehui, Su Jie, Hao Aiyou*, Light-responsive drug carrier vesicles assembled by cinnamic acid-based peptide, Colloid and Polymer Science, 2013, 291(11): 2639-2646.
3. Li Liuzhong, Wu Yuxiang, Dong Qi, Hao Aiyou*, Cheng Ruihua, Zhong Lei, Liu Boping, Effect of Al-alkyl cocatalyst on ethylene polymerization behavior using silyl chromate (SC)/SiO2 catalyst, Asia-Pacific Journal of Chemical Engineering, 2013, 8(4): 539-546.
4. Tao Sun, Mingfang Ma, Hui Yan, Jian Shen, Jie Su, Aiyou Hao*, Vesicular particles directly assembled from the cyclodextrin/UR-144 supramolecular amphiphiles, Colloids and Surfaces A: Physicochemical and Engineering
Aspects, 2013, 424: 105-112.
5. Sun Tao, Yan Hui, Xing Pengyao, Su Jie, Li Shangyang, Hao Aiyou*, Cu(II)-triggered release of paclitaxel from a supramolecular complex，SUPRAMOLECULAR CHEMISTRY, 2013, 25(5): 302-309.
6. Pengyao Xing, Tao Sun, Shangyang Li, Aiyou Hao*, Jie Su, Yuehui Hou, An instant-formative heat-set organogel induced by small organic molecules at a high temperature, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2013, 421: 44-50.
7. Xing Pengyao, Li Shangyang, Xin Feifei, Hou Yuehui, Hao Aiyou*, Sun Tao, Su Jie, Multi-responsive supramolecular organogel with a crystalline-like structure, Carbohydr Res, 2013, 367: 18-24.
8. Xin Feifei, Xing Pengyao, Li Shangyang, Hou Yuehui, Hao Aiyou*, A facile method to construct dual-responsive organogels with color changes, RSC Advances, 2013, 3(44): 21959-21963.
9. Xing Pengyao, Chu Xiaoxiao, Li Shangyang, Xin Feifei, Ma Mingfang, Hao Aiyou*, Switchable and orthogonal self-assemblies of anisotropic fibers, New Journal of Chemistry, 2013, 37(12): 3949-3955.
10. Xing Pengyao, Chu Xiaoxiao, Li Shangyang, Hou Yuehui, Ma Mingfang, Yang Jingshu, Hao Aiyou*, Self-recovering beta-cyclodextrin gel controlled by good/poor solvent environments, RSC Advances, 2013, 3(44): 22087-22094.
11. Xing Pengyao, Sun Tao, Hao Aiyou*, Vesicles from supramolecular amphiphiles, RSC Advances, 2013, 3(47): 24776-24793.
12. Xing Pengyao, Chu Xiaoxiao, Du Guangyan, Li Mingzhi, Su Jie, Hao Aiyou*, Hou Yuehui, Li Shangyang, Ma Mingfang, Wu Le, Yu Qiubing, Controllable self-growth of a hydrogel with multiple membranes, RSC ADVANCES, 2013, 3(35): 15237-15244.
第一作者論文
1. 郝愛友，黃惠琴，林吉茂，馬晨，利用氯化鋅/微孔球狀矽膠色譜柱製備α-叔丁基醛酮，有機化學，1999，(04)：435-437。
2. 郝愛友，親核重排反應中氫的遷移能力，化學通報(網路版)，1999，-(c00037)：1-3。
3. AI-YOU HAO, JI-MAO LIN, LIN-HUI TONG, Selective arylation of β-CD with an ethylenediamino group and characteristics of arylated β-CD dervatives in host-guest complexation, Journal of Inclusion Phenomena and
Macrocyclic Chemistry, 1999, 34(-): 445-454.
4. Ai You Hao, Lin Hui TONG, Min ZHOU, Selective Modification of -CD on the Secondary Side 4: preparation of arylation of β-CD with a Flexible Chain, Chinese Chemical Letters, 1998, 9(1): 13-16.
5. Ai You HAO, Lin Hui TONG, Tian Lin YANG, Ji Mao LIN, Characteristic Studies of Arylated -Cyclodextrrins in Host-Guest Complexation with Small Molecules, Chinese Chemical Letters, 1998, 9(3): 265-268.
6. 郝愛友，童林薈，環糊精在環境保護中的功能套用，化學試劑，1997，(05)：302-303。
7. 郝愛友，童林薈，張復升，光譜活性化環糊精主體與過量客體複合作用性能的簡易數學表達式，化學物理學報，1996，(05)：450-452。
8. 郝愛友，童林薈，張復升，β－環糊精為TLC流動相添加劑分離對映體，化學通報，1996，(04)：16-18。
9. Ai-You HAO, Lin-Hui TONG, Yao-HONG FU, Xia-FEI LAO, Hou-Ming WU, Dimerization constant determination of 6-O-benzoyl-β-CD in aqueous solution, Chinese Chemical Letters, 1996, 7(9): 853-854.
10.Ai You Hao, Lin Hui Tong, Fu Sheng Zhang, Xing Ming Gao, Convenient preparation of monoacylated β-cyclodextrin (cyclomaltoheptaose) on the secondary hydroxyl side, Carbohydrate Research, 1995, 277(2): 333-337.
11. 郝愛友，童林薈，金道森，環糊精的第二面選擇性修飾方法新進展，合成化學，1995，-(03)：208-214。
12. 郝愛友，童林薈，金道森，2─氧─(2─羥基丙基)─β─環糊精的簡便合成及純化，化學試劑，1995，(03)：161-162。
13. 郝愛友，童林薈，張復升，金道森，親脂類分子增溶劑單2－氧一(2一羥基丙基)一β一環糊精(單2一HP一β一CD)的製備及其NMR表征，合成化學，1995，(04)：369-371。
14. 郝愛友，童林薈，高興明，張復升，β-萘甲醯化β-環糊精的分子識別性能研究，Acta Physico - Chimica Sinica，1995，(03)：202-205。
15. Ai-You Hao, Lin-Hui Tong, Fu-Sheng Zhang, Xing-Ming Gao, and Yoshihisa Inoue, Direct TLC sepration of selected six enantiomersof amino-acids using 2-o-[(R) -2-hydroxypropyl]-β-CD as a mobile phase additive, Analytical Letters, 1995, 28(11): 2041-2048.
16. Ai You HAO, Lin Hui TONG, Fu Sheng ZHANG, Dao Sen JIN, A Convenient synthesis of β-cyclodextrion 2- and 3-O-monobenzoate, Chinese Chemical Letters, 1994, 5(8): 645-645.
17. 郝愛友，張立新，張海光，化學滴定法測定羥乙基β-環糊精的平均取代度，套用化學，2002，(03)：301-303。
18. 郝愛友，王金山，用環糊精合成楔筒狀主體分子新模型，Acta Chimica Sinica，2002，60(8)：1536-1538。
19. 郝愛友，王金山，辛志榮，水溶性顯色型分子識別器--甲基紅基乙二胺基羥丙基-β-環糊精，Acta Chimica Sinica，2002，60(8)：1531-1535。
20. Ai You HAO, Jin Shan WANG, The Preparation of 2-O-Acetonyl-β-cyclodextrin as One Key Intermediate for Water Soluble β-Cyclodextrin Derivatives, 中國化學快報(英文版), 2002, 13(9): 832-835.
科研成果
已發表論文200餘篇及十餘項專利
專著：郝愛友，孫昌俊，曲榮軍，徐勝廣，劉希光，張文志，精編有機化學教程，山東大學出版社，845000字，2009。
所獲專利
1. 初曉曉，郝愛友，邢鵬遙，一種多重回響的自修複葉酸凝膠及其製備方法，2015.10.28，山東，ZL 2013 1 0595730.6。
2. 邢鵬遙，郝愛友，劉文奇，一種無毒穩定小分子有機凝膠及其製備方法，2013.11.6，山東，ZL 2012 1 082269.X。
3. 李尚洋，蘇傑，郝愛友，一種賴氨酸α-氨基的苄氧羰基高效選擇性保護方法及其產品，2013.7.3，山東，ZL 2011 1 0422510.4。
4. 邢鵬遙，孫濤，郝愛友，一種負載紫杉醇的囊泡的製備方法，2013.7.3，山東，ZL 2012 1 0082143.2。
5. 郝愛友，孫濤，趙文靜，一種二氮喹喔啉類化合物的製備方法，2010.6.9-2029.12.3，山東，ZL 2009 1 0230759.8。
6. 孫濤，郝愛友，一種對1-硝基蒽醌廢渣綜合利用的方法，2009.3.25-2028.10.15，山東，ZL 2008 1 0157831.4。
7. 郝愛友，申健，低聚乳酸基環糊精衍生物及其製備方法，2005.9.7-2025.2.21，山東，ZL 2005 1 0042460.1。
