苗志偉

苗志偉,男,出生於1969年3月16日,南開大學化學學院教授。

基本信息

人物簡介

苗志偉 教授 1991年和1998年畢業於天津師範大學化學系,分別獲得理學學士和碩士學位,2002年畢業於清華大學化學系,獲得理學博士學位,導師:趙玉芬院士。2002-2004年在瑞士聯邦蘇黎世高等理工大學(ETH Zürich)從事博士後研究,2004-2011年在南開大學化學學院元素有機化學研究所任副教授,2012年晉升為教授。主要從事有機磷化學及不對稱合成化學研究,已在國內外核心化學期刊上發表研究論文50餘篇,獲得國家發明專利5項。

研究方向

具有生物活性含磷化合物合成方法研究 。不對稱合成化學:

(1)糖手性誘導不對稱合成;

(2)有機小分子催化劑催化不對稱合成;

(3)金屬-配體絡合物催化不對稱合成。

研究成果

  • Shasha Kong, Weidong Fan, Guiping Wu, Zhiwei Miao,* “Enantioselective Synthesis of Tertiary α-Hydroxy Phosphonates Catalyzed by Carbohydrate/Cinchona Alkaloid Thiourea Organocatalysts” Angew. Chem. Int. Ed. 2012, 51, 8864-8867.
  • Haohao Yang, Bing Cui, Guiping Wu, Zhiwei Miao,* and Ruyu Chen* “Asymmetric aza-Friedel-Crafts Reaction of Indoles Induced by O-Pivaloylated D-Galactosylamine as the Chiral Auxiliary” Tetrahedron 2012, 68, 4830-4837.
  • Bin Cui, Shasha Kong, Guiping Wu, Zhiwei Miao,* and Ruyu Chen* “Lewis Acid Catalyzed Diastereoselective Vinylogous Mannich Reaction Induced by O-Pivaloylated D-Galactosylamine as the Chiral Auxiliary: Stereoselective Synthesis of 6-Arylpiperidin-2-ones” SYNTHESIS 2012, 44, 111
  • 其他研究成果

    論文標題 發表刊物 發表時間

    An Improved Route to the Synthetic of Diphenyl α-(Diethoxythiophosphorylamino)methylphosphonates Bioorganic Chemistry 2006-10-01

    Synthesis of diphenyl alpha-(dipropoxyphosphoramido)alkyl-phosphonates Chinese Journal of Chemistry 2007-04-01

    Synthesis and electrospray ionization mass spectra of N-(1,3,2-dioxaphosphorincin-2-ylmethyl)thiophosphoramidates Chinese Journal of Chemistry 2007-06-01

    Synthesis and structure of O,O-diethyl N-[(trans-4-aryl-5,5-dimethyl-2-oxido-2 lambda(5)-1,3,2-dioxaphosphorinan-2-yl)methyl]pho Helvetica Chimica Acta 2007-08-01

    Mannich type reactions of chlorophosphites, phosphoramides and aldehydes (ketones) under solvent-free and catalyst-free conditio Green Chemistry 2007-10-01

    Acetyl chloride mediated synthesis of trans-2-[(diethoxyphosphorylamino)alkyl]-4-aryl-5,5-dimethyl-1,3,2λ5-dioxaphosphorinane-2- Bulletin of Chemical Society of Japan 2008-05-01

    An Efficient and Green Method for the Synthesis of N-Phosphoramino o-Hydroxylphenyl α-Aminophosphonic Monoesters Heteroatom Chemistry 2008-05-01

    The diastereoselective synthesis of Methyl 5-deoxy-5-(dialkylphosphono)-5-(dialkylphosphorylamido)-2,3-O-isopropylidene-β-D-ribo Carbohydrate RESEARCH 2008-06-01

    Progress in the synthesis of isobenzopyran and isobenzofuran derivatives 有機化學 2008-08-01

    Glycosylation-Induced and Lewis Acid Catalyzed Asymmetric Synthesis of β-N-Glycosidically Linked α-Aminophosphonic Acids Derivat Advanced Synthesis & Catalysis 2008-09-01

    Efficient Syntheses of (Thio)phosphonylated Isobenzofurans by Tandem Nucleophilic Addition and Regioselective 5-Exo-dig Addition Advanced Synthesis & Catalysis 2008-10-01

    The Progress in Synthesis Derivatives of Isobenzopyran and Isobenzofuran 有機化學 2008-10-02

    Efficient Syntheses of Phosphonylated Isochromenes by Regioselective 6-Endo-dig Addition to Carbon-Carbon Triple Bond Catalyzed Organic & Biomolecular Chemistry 2009-06-21

    Stereoselective Synthesis of α-Amino(phenyl)methyl(phenyl)Phosphinic Acids with O-Pivaloylated D-Galactosylamine as Chiral Auxil Chem. Eur. J. 2009-08-12

    Highly Enantioselective Biginelli Reaction Promoted by Chiral Bifunctional Primary

    Solvent-Free Biginelli Reaction: A Green Method for the Synthesis of 3,4-Dihydropyrimidin-2-ones Catalyzed by Protic Acids in La Letters in Organic Chemistry 2011-04-13

    A Versatile and Efficient Cu-Catalyzed N-Arylation of Aromatic Cyclic Secondary Amines with Aryl Halides Letters in Organic Chemistry 2011-06-09

    Cross-Coupling Reactions of Aryl Halides with Amines, Phenols, and Thiols Catalyzed by an N,N’-Dioxide Eur. J. Org. Chem. 2011-07-06

    Highly efficient asymmetric vinylogous Mannich reaction induced by O-pivaloylated D-galactosylamine as the chiral auxiliary Org. Biomol. Chem. 2011-09-15

    Bifunctional primary amine-thiourea Org. Biomol. Chem. 2011-09-22

    Amine-Thiourea Catalysts: Asymmetric Synthesi Adv. Synth. Catal. 2009-10-06

    Asymmetric Mannich-Type Synthesis of N-Phosphinyl α-Aminophosphonic Acid Monoesters Helvetica Chimica Acta 2011-10-26

    Highly diastereoselective vinylogous Mukaiyama aldol reaction of α-keto phosphonates with 2-(trimethylsilyloxy)furan catalyzed b Org. Biomol. Chem. 2011-11-09

    Efficient Syntheses of 1H-isochromen-1-ylmethylphosphonates via Regioselective 6-endo-dig Addition to Carbon-carbon Triple Bond Phosphorus, Sulfur, and Silicon 2011-12-14

    Lewis Acid Catalyzed Diastereoselective Vinylogous Mannich Reaction Induced by O-Pivaloylated D-Galactosylamine as the Chiral Au SYNTHESIS 2012-04-19

    Asymmetric aza-Friedel-Crafts Reaction of Indoles Induced by O-Pivaloylated D-Galactosylamine as the Chiral Auxiliary Tetrahedron 2012-05-10 Enantioselective Synthesis of Tertiary α-Hydroxy Phosphonates Catalyzed by Carbohydrate/Cinchona Alkaloid Thiourea Organocatalys Angew. Chem. Int. Ed. 2012-08-15

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