人物履歷
2001年畢業於中國農業科學院研究生院,獲農學博士學位;
2001年進入北京大學博士後流動站;
2003年中國科學院動物研究所副研究員。主要從事發育生物學和細胞生物學研究,主要研究方向為:細胞核移植及重編程的分子機制、幹細胞和治療性克隆。
1991年起主持和參加了國家“863”項目、國家重點基礎研究發展規劃(973)項目、國家自然科學基金、“八五”農業部重點項目、“九五”農業部重點項目等10餘個項目的研究工作;發表論文30餘篇;獲黑龍江省科技進步一等獎1項、哈爾濱市科技進步二等獎1項。
研究領域
從事動物克隆、胚胎幹細胞培養、重編程的分子機制研究。
代表論著
Yang Yu, Jindao Wu, Yong Fan, Zhuo Lv, Xuejiang Guo, Chun Zhao, Rong Zhou, Zhuo Zhang, Fuqiang Wang, Min Xiao, Ling Chen, Hui Zhu, Wen Chen, Min Lin, Jiayin Liu, Zuomin Zhou, Liu Wang, Ran Huo, Qi Zhou*, Jiahao Sha. Evaluation of blastomere biopsy using mouse model indicates the potential high-risk of neurodegenerative disorders in the offspring. Mol Cell Proteomics. 2009 Mar 11. [Epub ahead of print]
Minyue Ma, Xuejiang Guo, Fuqiang Wang, Chun Zhao, Zichuan Liu, Zhonghua Shi, Yufeng Wang,Ping Zhang, Kemei Zhang, Ningling Wang, Min Lin, Zuomin Zhou, Jiayin Liu, Qingzhang Li, Liu Wang, Ran Huo, Jiahao Sha,and Qi Zhou*. Protein Expression Profile of the Mouse Metaphase-II Oocyte. J Proteome Res. 2008; 7(11): 4821-4830.
Qingyun Mai, Yang Yu, Tao Li, Liu Wang, Mei-jue Chen, Shu-zhen Huang, Canquan Zhou, Qi Zhou*. Derivation of human embryonic stem cell lines from parthenogenetic blastocysts. Cell Research. 2007; 17:1008-1019.
Yu Y, Ding C, Wang E, Chen X, Li X, Zhao C, Fan Y, Wang L, Beaujean N, Zhou Q, Jouneau A, Ji W. Piezo-assisted nuclear transfer affects cloning efficiency and may cause apoptosis. Reproduction. 2007 May;133(5):947-54.
Yang J, Yang S, Beaujean N, Niu Y, He X, Xie Y, Tang X, Wang L, Zhou Q*, Ji W*. Epigenetic marks in cloned rhesus monkey embryos: comparison with counterparts produced in vitro. Biol Reprod. 2007 76(1):36-42.
Zhao C, Yao R, Hao J, Ding C, Fan Y, Dai X, Li W, Hai T, Liu Z, Yu Y, Wang Y, Hou X, Ji W, Zhou Q, Jouneau A, Zeng F, Wang L*. Establishment of customized mouse stem cell lines by sequential nuclear transfer. Cell Res. 2007 Jan;17(1):80-7.
Wang ErYao, YU Yang, Li XueMei, JIAO LiHong, Wang Liu* Effects of different nuclear transfer and activation methods on the development of mouse somatic cell cloned embryos Chinese Science Bulletin. 2007, 52 (1) :1-6
Tianqing Li, Shufen Wang, Yunhua Xie, Yongqing Lu, Xiuzhen Zhang, Liu Wang, Shihua Yang, Don Wolf, Qi Zhou* and Weizhi Ji*,Transplantable neural progenitor populations derived from rhesus monkey embryonic stem cells.Stem Cells. 2005 Oct;23(9):1295-303. Epub 2005 Jul 28
Tianqing Li, Shufen Wang, Yunhua Xie, Yongqing Lu, Xiuzhen Zhang, Liu Wang, Shihua Yang, Don Wolf, Qi Zhou* and Weizhi Ji*, Homologous feeder cells support undifferentiated growth and pluripotency in monkey embryonic stem cells. Stem Cells. 2005 Sep;23(8):1192-9. Epub 2005 Jun 13
Wang L, Zheng A, Yi L, Xu C, Ding M, Deng H. Identification of potential nuclear reprogramming and differentiation factors by a novel selection method for cloning chromatin-binding proteins. Biochem Biophys Res Commun. 2004, 325(1): 302-7
L.Wang, G.Z.Tong, H.Q.Liu, Z.B.Yang, H.J.Qiu, X.G.Kong, M.Wang., Proviral Genomic Sequence Analysis of Chinese Donkey Leukocyte Attenuated Equine Infectious Anemia Virus Vaccine and its Parental Virus Strain Liaoning. Science in China. Series C-life sciences, 2002, 45(1): 57-67.