![王春明[蘭州大學生命科學學院副教授]](/img/c/85d/nBnauM3X3ETM1kTO0YjM1kTO0UTMyITNykTO0EDMwAjMwUzL2IzLzMzLt92YucmbvRWdo5Cd0FmL0E2LvoDc0RHa.jpg "王春明[蘭州大學生命科學學院副教授]")
人物經歷
1988.8-1992.6 蘭州大學生物系細胞生物學專業，獲學士學位。
1999.9-2004.6 蘭州大學生命科學學院細胞生物學專業，獲理學博士學位。
2005.7-2007.1 新加坡國立大學醫學院生理學系，作為Research Fellow從事線粒體解偶聯蛋白（UCP）功能方面以及巨大阿米巴變形蟲線粒體內膜立體結構與氧化脅迫的關係研究。
1992.6-1999.7 唐山市冀東製藥廠。
2004.7-至今 蘭州大學生命科學學院生物物理研究所副教授。
研究方向
現主要研究方向為線粒體自由基相關的天然產物抗氧化機理與衰老和腫瘤關係研究。理論方面重點從線粒體內膜解偶聯蛋白表達調控角度探討自由基與衰老、壽命及腫瘤的關係，實踐方面主要從中藥天然產物對端粒長度、端粒酶活性、細胞分化、血管生成以及細胞凋亡等方面的影響研究和開發天然產物的生物學活性。
主要貢獻
王春明, 鄭榮梁. 種間對比研究方法闡明解偶聯蛋白與最大壽命的關係. 中國老年學雜誌 2011; 31: 348-350. （Wang CM, Zheng RL. Clarifying the relationship between uncoupling protein and maximum lifespan with interspecies comparitive research. Chinese Journal of Gerontology 2011; 31: 348-350 (Chinese).）
Wang CM, Almsherqi ZA, McLachlan CS, Matthews S, Ramachandran M, Tay S, Deng Y. Acute starvation in C57BL/6J mice increases myocardial UCP2 and UCP3 protein expression levels and decreases mitochondrial bio-energetic function. Stress 2011; 14: 66-72.
趙晶, 蒲麗平, 楊精濤, 劉權, 高清祥, 王勤, 王春明. 2種苯並呋喃衍生物對肝癌細胞的毒性及活性氧機制. 中國實驗方劑學雜誌 2010; 16: 105-108.（Zhao J, Pu LP, Yang JT, Liu Q, Gao QX, Wang Q, Wang CM. Cytotoxicity and reactive oxygen species related mechanism on HepG2 cells of two benzofuran derivatives. Chinese Journal of Experimental Traditional Medical Formulae 2010; 16: 105-108 (Chinese).）
王春明, 陳和平, 鄭榮梁. 自由基醫學理論用於“治未病”的探討. 中國預防醫學雜誌 2009; 10: 685-688.（Wang CM, Chen HP, Zheng RL. Perspective of treating pre-disease with free radical theory of medicine. Chin Prev Med 2009; 10: 685-688 (Chinese).）
Wang CM, Almsherqi ZA, Slocinska MB, Tan OLL, Cheong YMC, Deng Y. Uncoupling Protein May Contribute to the Much Longer Maximum Life Span Potential of Canary Than Mouse. In: Proceedings of the XIV Biennial Meeting of the Society for Free Radical Research International; 2008: 147-152.
Wang CM, Jia ZJ, Zheng RL. The effect of 17 sesquiterpenes on cell viability and telomerase activity in the human ovarian cancer cell line HO-8910. Planta Medica 2007; 73: 180-184.
Wang CM, Almsherqi ZA, Kua CH, Tan OL, Meng CCY, Deng Y. Effects of starvation on heart mitochondrial proton leak and uncoupling protein expression in canary birds and mice. Biochimica Et Biophysica Acta-Bioenergetics 2006: 395-395.
王春明, 鄭榮梁. 衰老和癌變過程中自由基與端粒和端粒酶的關係研究進展. 自由基生命科學進展 2004; 10: 26-31.（Wang CM, Zheng RL. The relationship between free radicals and telomere/telomerase in aging and carcinogenesis. Progress in Free Radical Life Sciences 2004; 10: 26-31 (Chinese).）
Wang CM, Hua W, We YM, Jia ZJ, Zheng RL. In vitro effects on proliferation, telomerase activity and apoptosis of an eremophilanoid sesquiterpene from Senecio oldhamianus Maxim in cultured human tumor cell lines. Pharmazie 2004; 59: 802-806.
王春明, 陳興, 王瑛, 賈忠建, 鄭榮梁. 離舌橐吾中3種倍半萜的體外抗癌活性. 蘭州大學學報(自然科學版) 2002; 38: 123-124.（Wang CM, Chen X, Wang Y, Jia ZJ, Zheng RL.In vitroanti-cancer effect of 3 sesquiterpenes isolated fromLigularia veitchiana(Hemsl) Greenm. Journal of Lanzhou University (Natural Sciences) 2002; 38: 123-124 (Chinese).）
常城, 王春明. 缺血再灌注損傷的自由基機制. In: 鄭榮梁, 黃中洋 (eds.), 自由基生物學, vol. 第三版. 北京: 高等教育出版社; 2007: 260-266.（Chang C, Wang CM. the Free Radical Mechanisms of Ischemia Reperfusion. In: Zheng R-L, Huang C-Y (eds.), Free Radical Biology, Three ed. Beijing: Higher Education Press; 2007: 260-266 (Chinese).）
Li PL, Wang CM, Zhanga ZX, Jia ZJ. Five new eremophilane derivatives from Ligularia sagitta. Tetrahedron 2007; 63: 12665-12670.
Cheong CM, Wang CM, Almsherqi Z, Deng Y. Tocopherylquinone activates uncoupling protein in myocardial mitochondria: A potential new role of vitamin E as an antioxidant. Biochimica Et Biophysica Acta-Bioenergetics 2006: 381-382.
Wu QH, Wang CM, Cheng SG, Gao K. Bieremoligularolide and eremoligularin, two novel sesquiterpenoids from Ligularia muliensis. Tetrahedron Letters 2004; 45: 8855-8858.
Min Y, Wang CM, Qi Z, Han YF, Jia ZJ. Sesquiterpenes, lignans and other constituents from Saussurea macrota. Pharmazie 2004; 59: 972-976.
Yang C, Wang CM, Jia ZJ. Sesquiterpenes and other constituents from the aerial parts of Inula japonica. Planta Medica 2003; 69: 662-666.
Wang WS, Gao K, Wang CM, Jia ZJ. Cytotoxic triterpenes from Liguladopsis shichuana. Pharmazie 2003; 58: 148-150.
Yang H, Wang CM, Jia ZJ, Shi YP. Four new eremophilanoid sesquiterpenes from Senecio oldhamianus. Acta Chimica Sinica 2001; 59: 1686-1690.
