人物經歷
1989年9月-1993年7月,廣西師範大學化學系,獲理學學士
1993年9月-1996年7月,廣西師範大學化學系,獲理學碩士,有機化學(藥物合成)
1996年8月-1999年2月,廣西師範大學化學化工系,講師,有機化學
1999年3月-2001年12月,中國科學院昆明植物研究所,獲理學博士,植物化學
2002年1月-2003年6月,中國科學院昆明植物研究所,助理研究員,植物化學,天然產物化學
2003年7月-2004年2月,中國科學院昆明植物研究所,副研究員,植物化學,天然產物化學
2004年3月-2004年9月,香港中文大學中醫學院,博士後,高等真菌的次生代謝產物
2004年10月-2006年3月,德國萊布尼茲天然產物及感染生物學研究所生物有機化學系,DAAD-Leibniz博士後,微生物次生代謝產物
2006年4月-2007年7月,德國馬普化學生態研究所生物化學系,博士後,化學生態學
2007年11月--,雲南大學生物資源保護與利用重點實驗室,研究員,次生代謝產物及功能
EDUCATIONANDEXPERIENCE:
09/1989-07/1996,StudiesofChemistryatDepartmentofChemistry,GuangxiNormalUniversity,China:
Master’sthesison'synthesisofallantoin’
07/1996-03/1999,LectureratDepartmentofChemistry,GuangxiNormalUniversity,Guilin,China
03/1999-12/2001,PhDthesisatStateKeyLaboratoryofPhytochemistryandPlantResourcesinWestChina,KunmingInstituteofBotany,TheChineseAcademyofSciences
01/2002-06/2003,AssistantProfessoratStateKeyLaboratoryofPhytochemistryandPlantResourcesinWestChina,KunmingInstituteofBotany,TheChineseAcademyofSciences
07/2003-12/2007,AssociateProfessoratStateKeyLaboratoryofPhytochemistryandPlantResourcesinWestChina,KunmingInstituteofBotany,TheChineseAcademyofSciences
03/2004-09/2004,PostdoctoralFellowatSchoolofChineseMedicine,TheChineseUniversityofHongkong,
10/2004-03/2006,PostdoctoralFellowatLeibnizInstituteforNaturalProductResearchandInfectionBiologyHans-Kn?ll-Institute(HKI),Jena,Germany
04/2006-07/2007,PostdoctoralFellowatDepartmentofBiochemistry,&ResearchGroupBiosynthesis/NMR,MaxPlanckforChemicalEcology,Jena,Germany
11/2007-present,ProfessoratLaboratoryforConservationandUtilizationofBio-resources,YunnanUniversity,Kunming,China
AWARD：
2004.10-2006.3,PostdocoralfellowshipbyGermanAcademicExchangeService(DeutscherAkademischerAustauschdienst,DAAD)-Leibniz
研究方向
微生物和植物中的天然產物的分離和結構鑑定
捕食線蟲真菌的化學防禦機制
套用酶和微生物的生物轉化
植物與相關微生物之間的化學相互作用
RESEARCHINTERESTS：
IsolationandstructureelucidationofnaturalproductsfrommicroorganismsandplantsinYunnan
Useofenzymesandmicroorganismsforbiotransformations
Chemicaldefensemechanismofnematode-trappingfungi
Chemicalinteractionbetweenplantsandtheassociatedmicroorganisms
參研項目
目前承擔或參與國家自然科學基金委、雲南省科技廳等在研項目。
PUBLICATIONS(2002-):
1.WuDK,ZhangCP,ZhuCY,WangYL,GuoLL,ZhangKQ,andNiuXM*.MetabolitesfromCarnivorousFungusArthrobotrysentomopagaandTheirFunctionalRolesinFungalPredatoryAbility,J.Agric.FoodChem.2013,61,4108−4113.(*correspondingauthor)
2.LuoSH,HuaJ,NiuXM,LiuY,LiCH,ZhouYY,JingSX,ZhaoX,LiSH,DefensesesterterpenoidlactonesfromLeucosceptrumcanum,Phytochemistry,2013,86,29-35.
3.TanJL,NiuXM,YangGY,WangL,DuanYX,HanY,ZhangKQ,ZhangCM.QuantitativeDeterminationofPhytosterolsinTobaccoLeavesbyUPLC-MS/MS.JLiqChromatogrRT,2013,36,591-599.
4.GuoJP,ZhuCY,ZhangCP,ChuYS,WangYL,ZhangJX,WuDK,ZhangKQ,NiuXM*.Thermolides,PotentNematocidalPKS-NRPSHybridMetabolitesfromThermophilicFungusTalaromycesthermophilus,JAmChemSoc,2012,134(50),20306-20309.(*correspondingauthor)
5.ZhangHX,TanJL,WeiLX,WangYL,ZhanCP,WuDK,ZhuCY,ZhangY,ZhangKQ,NiuXM*.MorphologyRegulatoryMetabolitesfromArthrobotrysoligospora.JNatProd,2012,75(7),1419-1423.(*correspondingauthor)
6.WuHY,WangYL,TanJL,ZhuCY,LiDX,HuangR,ZhangKQ,NiuXM*.RegulationoftheGrowthofCottonBollwormsbyMetabolitesfromanEntomopathogenicFungusPaecilomycescateniobliquus.JAgricFoodChem,2012,60(22),5604-5608.(*correspondingauthor)
7.LuoSH,LiuY,HuaJ,NiuXM,JingSX,ZhaoX,SchneiderB,GershenzonJ,LiSH,UniqueProline-BenzoquinonePigmentfromtheColoredNectarof"Bird'sCocaColaTree"FunctionsinBirdAttractions.OrganicLett,2012,14(16),4146-4149.
8.LiSH,NagyNE,HammerbacherA,KrokeneP,NiuXM,GershenzonJ,SchneiderB.LocalizationofPhenolicsinPhloemParenchymaCellsofNorwaySpruce(Piceaabies),ChemBioChem,2012,13,2707-2713.
9.GuoJP,TanJL,WangYL,WuHY,ZhangCP,NiuXM*,PanWZ,HuangXW,ZhangKQ.IsolationofTalathermophilinsfromaThermophilicFungusTalaromycesthermophilusYM3-4.JNatProd,2011,74(10),2278-2281.(*correspondingauthor)
10.WeiLX,ZhangHX,TanJL,ChuYS,LiN,XueHX,WangYL,NiuXM*,ZhangY,ZhangKQ.ArthrobotrisinsA-C,OligosporonsfromtheNematode-TrappingFungusArthrobotrysoligospora.JNatProd,2011,74(6),1526-1530.(*correspondingauthor)
11.NiuXM,ZhangKQ.Arthrobotrysoligospora:aModelOrganismforUnderstandingtheInteractionbetweenFungiandNematodes.Mycology,2011,2(2),59-78.
12.NiuQH,TianYX,ZhangL,XuXE,NiuXM,ZhangKQ,HuangXW.OverexpressionoftheKeyVirulenceProteasesBace16andBae16inBacillusnematocidaB16toImproveitsNematocidalActivity.JMolMicrobBiotech,2011,21,130-137.
13.YangJK,WangL,JiXL,FengY,LiXM,ZouCG,XuJP,RenY,MiQL,WuJL,LiuSQ,LiuY,HuangXW,WangHY,NiuXM,LiJ,LiangLM,LuoYL,JiKF,ZhouW,YuZF,LiGH,LiuYJ,LiL,QiaoM,FengL,ZhangKQ.GenomicandProteomicAnalysesoftheFungusArthrobotrysoligosporaProvideInsightsintoNematode-TrapFormation.PlosPathog,2011,7,e1002179.
14.YangJK,ZhaoXN,LiangLM,XiaZY,LeiLP,NiuXM,ZouCG,ZhangKQ.OverexpressionofaCuticle-DegradingProteaseVer112IncreasestheNematicidalActivityofPaecilomyceslilacinus.ApplMicrobiolBiot,2011,89,1895-1903.
15.LiGH,YangZS,ZhaoPJ,ZhengX,LuoSL,SunR,NiuXM,ZhangKQ.ThreeNewAcoraneSesquiterpenesfromTrichodermasp.YMF1.02647.PhytochemistryLett,2011,4,86-88.
16.ChuYS,NiuXM*,WangYL,GuoJP,PanWZ,HuangXW,ZhangKQ.IsolationofPutativeBiosyntheticIntermediatesofPrenylatedIndoleAlkaloidsfromaThermophilicFungusTalaromycesthermophilus.OrganicLett,2010,12(19),4356-4359.(*correspondingauthor)
17.NiuXM,WangYL,ChuYS,XueHX,LiN,WeiLX,MoMH,ZhangKQ.NematodetoxicAurovertin-TypeMetabolitesfromaRoot-KnotNematodeParasiticFungusPochoniachlamydosporia.JAgricFoodChem,2010,58(2),828-834.
18.LiCH,NiuXM,LuoQ,XieMJ,LuoSH,ZhouYY,SHLi.NovelPolyesterified3,4-seco-GrayananeDiterpenoidsasAntifeedantsfromPierisformosa.OrganicLett,2010,12(10),2426-2429.
19.LuoSH,LuoQ,NiuXM,XieMJ,ZhaoX,SchneiderB,GershenzonJ,LiSH.GlandularTrichomesofLeucosceptrumcanumHarborDefensiveSesterterpenoids.AngewChemIntEdit,2010,49,4471-4475.
20.NiuQH,HuangXW,ZhangL,XuJP,YangDM,WeiKB,NiuXM,AnZQ,BennettJW,ZouCG,YangJK,ZhangKQ.ATrojanHorseMechanismofBacterialPathogenesisagainstNematodes.ProcNatlAcadSciUSA,2010,107(38),16631-16636.
21.YangZS,LiGH,ZhaoPJ,ZhengX,LuoSL,LiL,NiuXM,ZhangKQ.NematicidalactivityofTrichodermaspp.andIsolationofanActivecompound.WorldJMicrobBiot.2010,26,2297-2302.
22.MiQL,YangJK,YeFP,GanZW,WuCW,NiuXM,ZouCG,ZhangKQ.CloningandOverexpressionofPochoniachlamydosporiaChitinaseGenePcchi44,aPotentialVirulenceFactorinInfectionagainstNematodes.ProcessBiochem,2010,45(5),810-814.
23.ZhaoX,ZhengGW,NiuXM,LiWQ,WangFS,LiSH,TerpenesfromEupatoriumadenophorumandtheirAllelopathicEffectsonArabidopsisSeedsGermination.JAgricFoodChem,2009,57,478-482.
24.NiuXM,DahseHM,MenzelKD,LozachO,WaltherG,MeijerL,GrableyS,SattlerI.ButyrolactoneIDerivativesfromAspergillusterreusCarryinganUnusualSulfateMoiety,JNatProd,2008,71,689-692.
25.HuangXS,HeJ,NiuXM,MenzelKD,DahseHM,GrableyS,FiedlerHP,SattlerI,HertweckC.Benzopyrenomycin,aCytotoxicBacterialPolyketideMetabolitewithaBenzo[a]pyrene-TypeCarbocyclicRingSystem.AngewChemIntEdit,2008,47,1-5.
26.LiSH,NiuXM,ZahnS,GershenzonJ,WestonJ,SchneiderB.DiastereomericStilbeneGlucosideDimersfromtheBarkofNorwaySpruce(Piceaabies).Phytochemistry,2008,69,772-782.
27.NiuXM,LiSH,GörlsH,SchollmeyerD,HilligerM,GrableyS,SattlerI.AbyssomicinE,aHighlyFunctionalizedPolycyclicMetabolitefromStreptomycesspecies.OrganicLett,2007,9(13),2437-2440.
28.NiuXM,LiSH,SunHD,CheCT.TwonewLanostanoidsfromGanodermaresinaceum.JAsianNatProdRes,2007,9(7),659-664.
29.ZhaoY,NiuXM,QianLP,LiuZY,ZhaoQS,SunHD.SynthesisandCytotoxicityofSomeNewEriocalyxinBDerivatives.EuroJMedChem,2007,42(4),494-502.
30.NiuXM,LiSH,SunHD,CheCT.PrenylatedPhenolicsfromGanodermafornicatum.JNatProd,2006,69(9),1364-1365.牛雪梅老師介紹。
