基本情況
林英武，男，1976年6月16日生，安徽安慶人，博士，南華大學副教授，碩士生導師，湖南省青年骨幹教師，南華大學生命科學中心副主任，無機與分析化學研究所所長。2005年12月博士畢業於復旦大學化學系，導師黃
主持基金項目
1.國家自然科學基金青年基金項目
2.南京大學配位化學國家重點實驗室開放基金項目
3.湖南省自然科學青年基金項目
4.湖南省教育廳青年基金項目
代表性SCI論文
201233. Lin ying-Wu*, Nie Chang-Ming, Liao Li-Fu. Rational design of a nitrite reductase based on myoglobin: A molecular modeling and dynamics simulation study. J Mol Model, 2012, DOI: 10.1007/s00894-012-1451-y.
32. Guo Wei-Wei, Wan Dun, Liao Li-Fu, Lin Ying-Wu*. Unusual peroxidase activity of a myoglobin mutant with two distal histidines. Chin Chem Lett, 2012, in press
31. Wan Dun, Liao Li-Fu, Zhao Min-Min, Wu Min-Long, Wu Yi-Mou, Lin Ying-Wu*. Interactionsof uranyl ion with cytochrome b5 and its His39Ser variant as revealed by molecular simulation in combination with experimental methods. J Mol Model, 2012, 18(3): 1009-1013.
30. Lin Ying-Wu*, Wu Yi-Mou, Liao Li-Fu, Nie Chang-Ming. Molecular modeling of cytochrome b5 with a single cytochromec-like thioether linkage. J Mol Model, 2012, 18(4):1553-1560.
29. Lin Ying-Wu*, Wu Yi-Mou, Liao Li-Fu. Dynamics comparison of two myoglobins with a distinct heme active site. J Mol Model, 2012, 18(4):1591-1596.
28. 林英武*. 細胞色素b5－蛋白質相互作用研究. 化學進展, 2012, 24(4): 147-155.
27. 林英武*. 計算機輔助蛋白質分子理性設計：從肌紅蛋白到一氧化氮還原酶. 化學進展, 2012,24(5): 129-134.
26. Minmin Zhao, Lifu Liao*, Minlong Wu, Yingwu Lin, Xilin Xiao, Changming Nie. Double-receptor sandwich labeled supramolecule assay of ATP based on uranyl-salophen complex and aptamer. Biosens. Bioelectron.2012, 34: 106-111.
25. Minlong Wu, Lifu Liao*, Minmin Zhao, Yingwu Lin, Xilin Xiao, Changming Nie. Separation and determination of trace uranium using a double-receptor sandwich supramolecule method based on immobilized salophen and fluorescence labeled oligonucleotide. Analytica Chimica Acta, 2012, in press.
24. Zhiyuan Zhao, Lifu Liao*, Xilin Xiao, Nan Du, Yingwu Lin. Determination of uranium in water based on enzyme inhibition using a wireless magnetoelastic sensor. intern. J. Environ. Anal. Chem. 2012, DOI:10.1080/03067319.2011.649742.
23. Nan Du, Lifu Liao*, Yongjun Xiao, Xilin Xiao, Zhiyuan Zhao, Yingwu Lin, Changming Nie. Developing a wireless sensing method for the measurement of gamma radiation dose based on the polymerization of acrylamide. Radiation Measurements, 2012, in press.
22. Lin Ying-Wu*. Structural insights into a low-spin myoglobin variant with bis-His coordination from molecular modeling. Proteins, 2011, 79(3): 679-684.
21. Lin Ying-Wu*, Nie Chang-Ming, Liao Li-Fu. Insights into uranyl ion binding to ubiquitin from molecular modeling and dynamics simulations. Chem Lett, 2011,40(12):1330-1331.
20. Lin Ying-Wu*,Ying Tian-Lei, Liao Li-fu.Molecular modeling and dynamics simulation of a histidine-tagged cytochrome b5. J Mol Model, 2011, 17(5):971-978.
19. Lin Ying-Wu*, Liao Li-Fu. Probing interactions between uranyl ions and lipid membrane by molecular dynamics simulation. Comput Theo Chem,2011,976(1-3): 130-134.
18. Hayashi Takahiro, Miner Kyle D, Yeung Natasha, Lin Ying-Wu, Lu Yi, Moenne-Loccoz Pierre*. Spectroscopic characterization of mononitrosyl complexes in heme-nonheme diiron centers within the myoglobin scaffold (FeBMbs): relevance to denitrifying NO reductase. Biochemistry, 2011, 50(26):5939-5947.
17. Ying-Wu Lin, Natasha Yeung, Yi-Gui Gao, Kyle D. Miner, Shiliang Tian, Howard Robinson, and Yi Lu*. Roles of glutamates and metal ions in a rationally designed nitric oxide reductase based on myoglobin. Proc Natl Acad Sci USA, 2010, 107(19): 8581-8586.
16. Ying-Wu Lin, Natasha Yeung, Yi-Gui Gao, Kyle D. Miner, Lanyu Lei, Howard Robinson, and Yi Lu*. Introducing a non-heme iron center into myoglobin confers nitric oxide reductase activity. J Am Chem Soc, 2010, 132(29): 9970-9972.
15. 林英武*. 蛋白質功能的擴展與人工金屬結合位點的理性設計. 化學進展, 2010, 22(6): 1203-1211.
14. Natasha Yeung, Ying-Wu Lin, Yi-Gui Gao, Xuan Zhao, Brandy S. Russell, Lanyu Lei, Kyle D. Miner, Howard Robinson, and Yi Lu*. Rational design of a structural and functional nitric oxide reductase. Nature,2009, 462(7276): 1097-1082.
13. Lin Ying-Wu*, Nie Chang-Ming, Liao Li-Fu. Folding behaviors of apocytochrome b5 and its mutants: Insights from high temperature molecular dynamics simulations. J Mol Struct THEOCHEM, 2009, 910(1-3): 154-162.
12. Lin Ying-Wu*, Ni Feng-Yun, Ying Tian-Lei. Early events in thermal unfolding of apocytochrome b562 and its double-cysteine mutant as revealed by molecular dynamics simulation. J Mol Struct THEOCHEM, 2009, 898(1-3): 82-89.
11. Lin Ying-Wu*, Ying Tian-Lei, Liao Li-Fu. Dynamic consequences of mutating the typical HPGG motif of apocytochrome b5 revealed by computer simulation. Chin Chem Lett, 2009, 20(5): 631-634.
10. Ying Tianlei, Wang Zhong-Hua, Lin Ying-Wu, Xie Jin, Tan Xiangshi*, Huang Zhongxian*. Tyrosine-67 in cytochrome c is a possible apoptotic trigger controlled by hydrogen bonds via a conformational transition.Chem Commun, 2009, 30: 4512-4514.
9. Lin Ying-Wu*, Wang Zhong-Hua, Ni Feng-Yun, Huang Zhong-Xian. Forced unfolding of apocytochromeb5 by steered molecular dynamics simulation.Protein J,2008, 27(3): 197-203.
8. Lin Ying-Wu*,Nie Chang-Ming, Liao Li-Fu.Probing the weak interactions between amino acids and carbon monoxide. Chin Chem Lett, 2008, 19(1): 119-122.
7. Jintao Yuan, Lifu Liao, Yingwu Lin, Changai Deng, Bo He. Determination of Sudan I in chilli powder from components gradual change–visible spectra data using second order calibration algorithms.Analytica Chimica Acta, 2008, 607(2): 160-167.
6. 林英武*，王中華，聶長明，倪峰雲。取代基對卟吩結構和性能的影響，物理化學學報，2007, 23 (10), 1594-1598.
5. Wang Zhong-Hua, Lin Ying-Wu, Rosell Federico I., Ni Feng-Yu, Lu Hao-Jie, Yang Peng-Yuan, Tan Xiang-Shi, Li Xiao-Yuan, Huang Zhong-Xian*, Mauk A. Grant. Converting cytochrome c into a peroxidase-like metalloenzyme by molecular design. ChemBioChem,2007,8(6): 607-609.
4. 林英武，黃仲賢。血紅素蛋白的分子設計新趨向。化學進展，2006, 18 (6): 794-800.
3. Lin Ying-Wu, Zhao Dong-Xin, Wang Zhong-Hua, Yu Wen-Hao, Huang Zhong-Xian*. Expression of lipase-solubilized bovine liver microsomal cytochrome b5 in Escherichia coli as a glutathione S-transferase fusion protein (GST-cyt b5). Protein Express Purif, 2006, 45(2): 352-358.
2. Lin Ying-Wu, Wang Wen-Hu. Zhang Qi. Lu Hao-Jie, Yang Peng-Yuan, Xie Yi, Huang Zhong-Xian*, Wu Hou-Ming*. Converting cytochrome b5 into cytochrome c-like protein.ChemBioChem,2005, 6(8): 1356-1359.
1. Lin Y*, Zhang X, Li J, Yin D, Wang Y. Preparation and radiolabeling of antimony sulfide nanocolloids with two different particle sizes.Appl Radiat Isotop,2003, 58(3): 347-352.
