人物經歷
2002年,美國耶魯大學訪問學者/博士後。
2000年— ,清華大學生命科學學院副教授。
研究方向
利用哺乳動物細胞和小鼠模型開展細胞信號轉導機制的研究,特別是在兩個方面:1. 視網膜發育及神經系統疾病相關的新基因功能及調控網路的研究;2. 腫瘤形成及轉移相關的細胞信號轉導機制的研究。
主要貢獻
論文
Mingxue Zhou*, Yifeng Wang*, Shaoling Qi, Jian Wang, Shuping Zhang . The expression of a mitochondria-localized glutamic acid-rich protein (MGARP/OSAP) is under the regulation of the HPG axis. Endocrinology. 2011. 2011, 152(6). (* Equal contribution)
Qi S, Wang Y, Zhou M, Ge Y, Yan Y, Wang J, Zhang SS, Zhang SP . A Mitochondria-localized glutamic acid-rich protein (MGARP/OSAP) is highly expressed in retina that exhibits a large area of intrinsic disorder. Mol Biol Rep. (2011) 38:2869-2877. [2010, Epub ahead of print].
Wang J,Qi SL, Cheng W, Li L, Wang F, Li YZ, Zhang SP . Identification, expression and tissue distribution of a renalase homologue from mouse, Mol Biol Rep. 2008, 35:613-20.
Zhang SP. A research-project-based and self-determined teaching system of molecular biology techniques for undergraduates, BMBE, 2008, 36(3):181-8.
Chen Y, Li YH, Chen XP, Gong LM, Zhang SP, Chang ZJ, Zhang XF, Fu XY, Liu L.,Point mutation at single tyrosine residue of novel oncogene NOK abrogates tumorigenesis in nude mice. Cancer Res. 2005, 65(23):10838-46.
Liu L, Yu XZ, Li TS, Song LX, Chen PL, Suo TL, Li YH, Wang SD, Chen Y, Ren YM, Zhang SP, Chang ZJ, Fu XY. A novel protein tyrosine kinase NOK that shares homology with platelet-derived growth factor/fibroblast growth factor receptors induces tumorigenesis and metastasis in nude mice. . 2004, 64(10):3491-9.