主研方向
1. 造血幹細胞移植及基因治療在白血病中的套用
2. 白血病細胞凋亡信號轉導機制及血液腫瘤的分子靶向治療。
3. 新型抗腫瘤、抗白血病藥物的分子作用靶點篩選。
社會兼職
1. SCI 雜誌 Anti-Cancer Drugs 編委（ 2009 年 IF:2.23 ）。
2. 教育部“中國科技論文線上”特邀評審專家。
3. British Journal of Hematology 、 International Journal of Cancer 、 Oncology 等多種雜誌審稿人。
4. 國家自然科學基金及廣東省自然科學基金評審專家。
5. 歐洲腫瘤協會抗癌分會國際會員。
6. 廣東省中西醫結合學會常委。
7. 廣州市抗癌協會血液腫瘤分會常委。
醫療專長
1.2004 年榮獲中山大學附屬三院優秀中青年醫師獎，是中山大學“千百十人才工程”培養對象。
2. 2006-2007 年以來被美國 Who's who in The Medicine and Healthcare （世界醫學與健康護理名人錄）收錄。
3. 2006 年被評為教育部“新世紀優秀人才”。
4. 2008 及 2009 年教育部“科技論文線上”優秀通訊評審專家。
論著
截至到目前為止，在國內外核心期刊發表學術論文 50 余篇 ( 第一作者 ), 其中 SCI 收錄 20 余篇。
以第一或通訊作者發表的主要代表論文（均為 SCI 收錄）有：
1. Antibody directed lentiviral mediated double suicide gene therapy in MUC-1 positive leukemia in vitro and in vivo. Cell Transplant 2011(In Press)
2. PPARγ Agonist Suppresses TLR4 Expression and TNF-α Production in LPS Stimulated Monocyte Leukemia Cells. Cell Biochem Biophys . 2010 Nov 23. [Epub ahead of print] ( 通訊作者 )。
3. Inactivation of PI3k/Akt signaling pathway and activation of caspase-3 are involved in tanshinone I-induced apoptosis in myeloid leukemia cells in vitro. Annals of Hematology 2010; 89(5):1089–1097. （通訊作者）
4. Down-Regulation of Telomerase Activity and Activation of Caspase Are Responsible for Tanshinone I-Induced Apoptosis in Monocyte Leukemia Cells. International Journal of Molecular Sciences 2010; 11(5): 2267-2280.
5. Activation ofperoxisome proliferator-activatedreceptor-gamma induces apoptosis on acute promyelocyti leukemia cells via downregulation of XIAP. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 2009; 24(5): 623-632.
6.Peroxisome Proliferator-ActivatedReceptor γ (PPAR-γ) Agonist Rosiglitazone (RGZ) Inhibits HL-60 Cell Growth by Induction of Apoptosis. Lab Medicine 2009; 40(5):297-302.
7. Tanshinone IIA inhibits leukemia THP-1 cell growth by induction of apoptosis. Oncology Reports 2009; 21(3): 1075-1081.
8.Peroxisome Proliferator-ActivatedReceptor-g Agonist Rosiglitazone–Induced Apoptosis in Leukemia K562 Cells and Its Mechanisms of Action. International Journal of Toxicology 2009; 28(2):123-131.
9. Ponicidin Inhibits Monocytic Leukemia Cell Growth by Induction of Apoptosis. International Journal of Molecular Sciences 2008 ; 9(11) : 2265-2277.
10. Downregulation of cyclooxygenase-2 expression and activation of caspase-3 are involved inperoxisome proliferator-activatedreceptor-gamma agonists induced apoptosis in human monocyte leukemia cells in vitro. Annals of Hematology 2007;86 (3):173-183.
11. Induction of apoptosis and inhibition of cell adhesive and invasive effects by tanshinone IIA in acute promyelocytic leukemia cells in vitro. Journal of Biomedical Science 2006; 13(12):813–823.
12. Antiproliferation Effects of Oridonin on HPB-ALL Cells and Its Mechanisms of Action. American Journal of Hematology 2006; 81(2):86–94.
13. Ponicidin, an Ent-Kaurane Diterpenoid Derived from a Constituent of the Herbal Supplement PC-SPES, Rabdosia rubescens , Induces Apoptosis by Activation of Caspase-3 and Mitochondrial Events in Lung Cancer Cells In Vitro. Cancer Investigation 2006; 24(2):136–148.
14. Expression of survivin and bax/bcl -2 in peroxisome proliferator activated receptor-{gamma} ligands induces apoptosis on human myeloid leukemia cells in vitro . Annals of Oncology 2005; 16(3):455-459.
15. Peroxisome proliferator activated receptor- ligands induced cell growth inhibition and its influence on matrix metalloproteinase activity in human myeloid leukemia cells. Cancer Chemotherapy and Pharmacology 2005;56(4):400-408.
16. Oridonin-induced apoptosis in leukemia K562 cells and its mechanism. Neoplasma 2005;52 (3):225-230.
17. Antiproliferation effects of ponicidin on human myeloid leukemia cells in vitro . Oncology Reports 2005; 13 (4):653-657.
18. Apoptotic effect of oridonin on NB4 cells and its mechanism. Leukemia & Lymphoma 2005; 46 (4): 593-597.
19. Antiproliferation effects of oridonin on HL-60 cells. Annals of Hematology 2004; 83(11):691-695.
20. Anti-proliferative effects of oridonin on SPC-A-1 cells and its mechanism of action. Journal of International Medical Research 2004; 32 (6):617-625.
21 . Oridonin Inhibit Cell Growth by Induction of Apoptosis on Human Carcinoma BEL7402 Cells. Hepatology Research . 2006;35(2)104-110.
22 . Oridonin-induced apoptosis of Jurkat cells and its mechanism. Comparative Pathology. 2004;13(2): 65-69.
專著
參編：《臨床症狀與體徵原理學》， 1998年，第一版，中國醫藥科技出版社。
參編：《診斷學複習指南》， 2001年，第一版，山東科技出版社。
