GM-CSF

GM-CSF是granulocyte-macrophage colony stimulating factor的縮寫，意思是粒細胞-巨噬細胞集落刺激因子，也指藥品沙格司亭。 對髓系幹細胞到成熟粒細胞的增殖與分化過程均有刺激作用。可促進髓系幹細胞向粒系（包括中性粒細胞、嗜酸粒細胞系）、紅素、巨核細胞系、粒單細胞系和單核細胞系的共同祖細胞分化，並促進以上各系造血定向幹細胞的增殖與成熟，對嗜鹼粒細胞的作用不明顯，對紅系晚期造血細胞的作用也較小。

[英漢醫學詞典]GM-CSF

[=granulocyte-macrophage colony stimulating factor]粒細胞-巨噬細胞集落刺激因子

[=granulocyte-macrophage colony stimuluting factor]顆粒球巨噬細胞株刺激因子,粒細胞巨噬細胞集落刺激因子

[=granular cell macrophages-colony stimulating factor]粒細胞巨噬細胞-集落刺激因子

[英文MESH詞典]GM-CSF

〖同義詞〗GM-CSF

〖主題詞〗Granulocyte-Macrophage Colony-Stimulating Factor

〖英文釋義〗An acidic glycoprotein of MW 23 kDa with internal disulfide bonds. The protein is produced in response to a number of inflammatory mediators by mesenchymal cells present in the hemopoietic environment and at peripheral sites of inflammation. GM-CSF is able to stimulate the production of neutrophilic granulocytes,macrophages,and mixed granulocyte-macrophage colonies from bone marrow cells and can stimulate the formation of eosinophil colonies from fetal liver progenitor cells. GM-CSF can also stimulate some functional activities in mature granulocytes and macrophages.

[英漢總索引詞典]GM-CSF

[英漢藥名關聯詞典]gm-csf

〖中文通用名〗沙格司亭

〖英文通用名〗sargramostim

〖所屬類別〗影響機體免疫功能的藥物/其它類