Overview
originally appeared in the Eastern Han Dynasty, Shen Nong Ben Cao Jing ":" To temper the heart evil under cold, warm, cold, dampness, Sanchong, long take a light body "originally appeared in the Eastern Han Dynasty, Shen Nong Ben Cao Jing ":" To temper the heart evil under cold, warm, cold, dampness, Sanchong, long take a light body "." from Lei Gongs Treatise On ":" Whoever causes needless - - while Chelsea is not - Su, up5 dogwood, just nuclear robusta is an uncommon nuclear medicinal cornel spermatorrhoea " from Lei Gongs Treatise On ":" Whoever causes needless - - while Chelsea is not - Su, up5 dogwood, just nuclear robusta is an uncommon nuclear medicinal cornel spermatorrhoea .
. Yuan Dynasty scientist WANG Hao - gu pointed out: "Slide is broken off, the astringent is so delicious - Yuan Dynasty scientist WANG Hao - gu pointed out: "Slide is broken off, the astringent is so delicious - .
dogwood also stop small convenience, Mysteries, the essence, and its sour flavor as a way to reduce also sliding" Qing Dynasty "materia medica" of personality: "nourish yin. The medicine is no laps, with the winner but also for medicinal herbs. The large kidney without heteroatoms, having neither the chills of the leaning back of yin or yang, nourishing Yin Zhu wears the crown". Tao:Zhu Dao mountains near a dogwood tree
sub, not dry - fruits, such as Red Elaeagnaceae, sub, not dry - fruits, such as Red Elaeagnaceae, . neither dry, the skin is very thin, when the core is to close with a ' neither dry, the skin is very thin, when the core is to close with a '.
Comaceae plant a total of 14 genera and more than 100 Chinese, there are 8 genera of Cornaceae plants, 50 kinds of Comaceae plant a total of 14 genera and more than 100 Chinese, there are 8 genera of Cornaceae plants, 50 kinds of . natural distribution in north temperate and subtropical mountains, China, Japan, North Korea, the United Kingdom, the United States of America natural distribution in north temperate and subtropical mountains, China, Japan, North Korea, the United Kingdom, the United States of America .
in China, mainly the Yangtze River, middle and lower reaches of the Yellow River at an altitude of 600 - 1400 of the shady, cool and wet, the leeward of the mountainous regions and hilly lands, which may be suitable for the warm, moist climates, with shade - tolerant plants, shade - loving, afraid of wet characteristics is a long - haired in China, mainly the Yangtze River, middle and lower reaches of the Yellow River at an altitude of 600 - 1400 of the shady, cool and wet, the leeward of the mountainous regions and hilly lands, which may be suitable for the warm, moist climates, with shade - tolerant plants, shade - loving, afraid of wet characteristics is a long - haired . Henan Xixia, Nanzhao,Neixiang, Luan Chuan;Zhejiang Linan An, etc;Shaanxi Foping, Danfeng, etc Henan Xixia, Nanzhao,Neixiang, Luan Chuan;Zhejiang Linan An, etc;Shaanxi Foping, Danfeng, etc .
the origin of Chinese traditional medicine on performance and efficacy of one of the important factors the origin of Chinese traditional medicine on performance and efficacy of one of the important factors . because of the environment, climate, temperature, moisture, sunlight, etc. of different natural conditions, the same kinds of herbs in the different areas of production, its quality is vastly different, as the previous emphasis on the origin of the
in Chinese herbs, Xixia, Henan, Shaanxi Foping, Zhejiang Linan of cornel with good quality and large quantity of total output in China, 90%, of the dogwood, three of which in Chinese herbs, Xixia, Henan, Shaanxi Foping, Zhejiang Linan of cornel with good quality and large quantity of total output in China, 90%, of the dogwood, three of which . dogwood, in appearance, with a height of 4 meters dogwood, in appearance, with a height of 4 meters .
twig bark, grey - brown branchlets glabrous; leaves simple twig bark, grey - brown branchlets glabrous; leaves simple .;Leaf blade elliptic or oblong, 5 - 7 cm long, as wide as 3 - 4 cm, apex narrow, long sharp - pointed shape, base rounded or broadly cuneate, entire, glabrous above, occasionally, by very fine, white hairs below, yellowish - brown tufts of hairs at axils of veins, lateral veins 5 - 7 pairs, arcuately parallel arrangement;petiole 1 cm long around ;Leaf blade elliptic or oblong, 5 - 7 cm long, as wide as 3 - 4 cm, apex narrow, long sharp - pointed shape, base rounded or broadly cuneate, entire, glabrous above, occasionally, by very fine, white hairs below, yellowish - brown tufts of hairs at axils of veins, lateral veins 5 - 7 pairs, arcuately parallel arrangement;petiole 1 cm long around .
open umbels, tuft on the top, with its lower counting buds scaly bracts;The flowers are small and;Calyx 4, is not significant;Petals 4, yellow;stamens 4;Ovary inferior open umbels, tuft on the top, with its lower counting buds scaly bracts;The flowers are small and;Calyx 4, is not significant;Petals 4, yellow;stamens 4;Ovary inferior . Drupe oblong, 1.2 - 1.5 cm, a diameter of about 7 mm, glabrous, red at maturity;carpopodium length 1. 5 - 2cm
Seeds long ellipsoid, rounded ends Seeds long ellipsoid, rounded ends . 5 - 6 months 5 - 6 months .
fruit from August to October 1 fruit from August to October 1 .
Drug Description
Drug name dogwood Pinyin: shan, zhu yu Drug name dogwood Pinyin: shan, zhu yu . Byname: Common Fruit, Fruit of the Common, Fruit of the Japanese, the Fruit of Byname: Common Fruit, Fruit of the Common, Fruit of the Japanese, the Fruit of .
A.Br. et Ascher.Cornus officinalis Sieb. Et Zucc. officinale (. Et Zucc.) Nakai ( efficiency classes: the experimental drug;Kidney - tonifying herbs on efficiency classes: the experimental drug;Kidney - tonifying herbs on .
Division belong to classification: medicinal plant of Cornaceae have been found in the alias Division belong to classification: medicinal plant of Cornaceae have been found in the alias .: Shu Zao, "real, murine, chicken feet, dogwood, jujubes, and jujube, jujube peel, jujube, jujube peel : Shu Zao, "real, murine, chicken feet, dogwood, jujubes, and jujube, jujube peel, jujube, jujube peel .
flavor: taste sour.The herb is mild in nature meridian tropism: liver; meridian tropism: liver;.
Kidney Functions: tonifying the liver and kidney;astringent Kidney Functions: tonifying the liver and kidney;astringent . Indication: waist dizzy;Deafness and tinnitus;soreness of waist and knees;Xian spermatorrhea semen;frequent urination;sweating more than;metrorrhagia and metrostaxis of woman Indication: waist dizzy;Deafness and tinnitus;soreness of waist and knees;Xian spermatorrhea semen;frequent urination;sweating more than;metrorrhagia and metrostaxis of woman .
Usage and Dosage: Oral: decocted in water, 5 - 10g;or into pill, powder and Usage and Dosage: Oral: decocted in water, 5 - 10g;or into pill, powder and . Ecological Environment: 400 - 1500m, dilute up to 2100m forest edges and forest resources or Ecological Environment: 400 - 1500m, dilute up to 2100m forest edges and forest resources or .
Location: Shanxi, Shaanxi, Gansu, Shandong, Anhui, Jiangxi, Henan, Hunan and Sichuan have Location: Shanxi, Shaanxi, Gansu, Shandong, Anhui, Jiangxi, Henan, Hunan and Sichuan have . .
Introduction and Cultivation of Artemisia source: as a medicinal plant of Cornaceae have been found in plants of dogwood fruit harvest Introduction and Cultivation of Artemisia source: as a medicinal plant of Cornaceae have been found in plants of dogwood fruit harvest . Store: seedling result to bring out the 6 - 7 years, 15 - 20 years before bearing.
| 9 - 11 months early fruit yield to red when mature, picking in batches, avoid damage to flower buds | 9 - 11 months early fruit yield to red when mature, picking in batches, avoid damage to flower buds . machining method may be water boiling;The red fresh fruit min in boiling water, blanch and soak in cold, hot extrusion of the seeds, pulp is dried in the sun or baking machining method may be water boiling;The red fresh fruit min in boiling water, blanch and soak in cold, hot extrusion of the seeds, pulp is dried in the sun or baking .
also mechanically threshing method, the extruded pulp drying also mechanically threshing method, the extruded pulp drying . processing methods: (1), pulp of dogwood fruit: Wash, pyrenes and removing impurities, drying in the sun processing methods: (1), pulp of dogwood fruit: Wash, pyrenes and removing impurities, drying in the sun .
2, medicinal wine: fetching the dogwood, yellow wine, stir in a sealed container, placed in the water, heat, simmer wine until exhaustion, taken out and dried (dogwood per 100 catties, with 20 - 25 kilograms of rice wine) 2, medicinal wine: fetching the dogwood, yellow wine, stir in a sealed container, placed in the water, heat, simmer wine until exhaustion, taken out and dried (dogwood per 100 catties, with 20 - 25 kilograms of rice wine) . 3, steamed Chinese - medicinal materials such as: fetching the dogwood, placed in a food heating steaming black cake, is removed, dried in the sun 3, steamed Chinese - medicinal materials such as: fetching the dogwood, placed in a food heating steaming black cake, is removed, dried in the sun .
Contraindication
1. Where the Mingmen exuberant fire, strong male not flaccidity, and gets a hot and humid, the shower pee - yin is a contraindication for 2, Annotation of Materia Medica ": one of the evil 2, Annotation of Materia Medica ": one of the evil .
platycodon grandiflorum, radix saposhnikoviae, radix stephaniae tetrandrae platycodon grandiflorum, radix saposhnikoviae, radix stephaniae tetrandrae .
Traditional Chinese Medicine Composition
Pulp of tannin - containing ingredients: Fructus Corni tanning Mao (-) 1, 2, 3, i.e. refers to its tannin dogwood 1 terchebin (), which is also referred to as tannin (Traga), Cornus officinalis tannins 2 while new Mitella (tel - II), i.e. 2 Cornus officinalis tannins are new Mitella (- I);(a) wood tannins (wood) A, B, C, G, and eugenol (tannin), Geum tannin) and D (2, 3 - di - O - galloyl - glucose (2, 3 - di - O - beta - D - glucose), 1, 2, 3 - tri - O - galloyl - glucose (1, 2, 6 - tri - O - -) - beta - D - glucose), 1, 2, 6 - dg - O - D - glucose), 1, 2, 6 - tri - O - galloyl - glucose (1, 2,6 - tetro - O - -) - beta - D - glucose) and sugary Glycosides;cornus officinalis glycosides (crack), morroniside (), 7 - O - methyl morroniside (7 - O -), glycoside (Nux Vomica), when the drug is (also) sugary Glycosides;cornus officinalis glycosides (crack), morroniside (), 7 - O - methyl morroniside (7 - O -), glycoside (Nux Vomica), when the drug is (also) .
dextrose (glucose), fructose (levulose), sucrose (su -), ursolic acid, gallic acid, malic acid (acid),(tartaric acid) and vitamin A (vitamin A) and the like containing the dextrose (glucose), fructose (levulose), sucrose (su -), ursolic acid, gallic acid, malic acid (acid),(tartaric acid) and vitamin A (vitamin A) and the like containing the . Bet, isolated from 9 of monoterpene hydrocarbons, sesquiterpene hydrocarbons of 6, 5, 7 of monoterpene ester and a fatty alcohol, aldehyde and ketone 4 monoterpenes, fatty aldehyde and a ketone of 3, 4 of 18 acid ester and an aromatic compound 15, wherein the contents of main components are: isobutyl (isobutyl alcohol), butanol (),iso - amyl alcohol (cetearyl alcohol), cis - and trans - forms for the conspiracy charge and borneol oxide (9.852%), furfural (), beta - beta - phenethylamine, (phenyl), (methyl), methyl eugenol, elemicin (), asarum herb (Li), palmitic acid ester (has been), oleic acid (ester),Isothiocyanate (linoleic acid), cinnamic acid and 2 - (benzyl) propenoate, hexadecanoic acid (palmitic acid), stearic acid (stearic acid), Wang (king) (bar) (allyl), alpha - terpineol (-) - alpha, alpha - curcumene (alpha), anethole (), 4 - methoxy - 1,2 - benzo - dioxol - (4 - methoxy - 1, - 2), asarum herb (ether), ketones (Aristolochiaceae), hexyl (vanillin), linolenic acid (ester), menthone (), safrole and the like) a
CONTAINING (linoleic acid), oleic acid (oleic acid), hexadecanoic acid (palmitic acid),Stearic acid (stearic acid), linolenic acid, linolenic acid, lauric acid (DI7) and fatty acids such as iron, aluminum, copper, zinc, boron and phosphorus concentrations of 21 elements CONTAINING (linoleic acid), oleic acid (oleic acid), hexadecanoic acid (palmitic acid),Stearic acid (stearic acid), linolenic acid, linolenic acid, lauric acid (DI7) and fatty acids such as iron, aluminum, copper, zinc, boron and phosphorus concentrations of 21 elements . and both contain) (threonine, valine, and leucine (LEUCINE), isoleucine (), Phenylalanine (), histidine, and lysine (lysine), serine (serine),- ic acid (glutamate), glycine (Gly), alanine (), tyrosine (tyrosine), arginine (Arg), aspartic acid and the like of amino acids, the nucleus also has another methionine (methionine), proline (proline), cystine ( and both contain) (threonine, valine, and leucine (LEUCINE), isoleucine (), Phenylalanine (), histidine, and lysine (lysine), serine (serine),- ic acid (glutamate), glycine (Gly), alanine (), tyrosine (tyrosine), arginine (Arg), aspartic acid and the like of amino acids, the nucleus also has another methionine (methionine), proline (proline), cystine (.
293. 15,303. 15,313. 15,323.
Pharmacological Action
Antibacterial
Fruit decoction can inhibit the growth of Staphylococcus aureus, Escherichia coli is invalid Fruit decoction can inhibit the growth of Staphylococcus aureus, Escherichia coli is invalid . decoction (1: 1) Shigella shigae inhibition zone, diameter up to 13 - 18 mm flat ring (cup) decoction (1: 1) Shigella shigae inhibition zone, diameter up to 13 - 18 mm flat ring (cup) .
from dogwood fruit flesh in a black - and - red sour liquid, typhoid, dysentery, bacterial inhibition from dogwood fruit flesh in a black - and - red sour liquid, typhoid, dysentery, bacterial inhibition . flooding agent (1: 3) in vitro on Trichophyton violaceum was different with flooding agent (1: 3) in vitro on Trichophyton violaceum was different with .
Hypoglycemic
outbred Wistar male rats, weighing 150 - 200 g, only 4 outbred Wistar male rats, weighing 150 - 200 g, only 4 . 36 divided by the total of group 1 was control group, the drug group, respectively, 5, 7.5, 15 g / (kg, d) the drug (dogwood flesh
mature after grinding with 70% ethanol reflux extraction, preparing extract, 1 ml (equivalent to USD 3. 5 g crude drug) ig drug group and control group. There was no significant difference in blood glucose level and the other had to
50 g / kg of the drug to rats ig1 Zhou, the result has not been seen in normal rats, in which the influence on 50 g / kg of the drug to rats ig1 Zhou, the result has not been seen in normal rats, in which the influence on . adrenaline in rats with hyperglycemia rats were divided equally into three groups, fasting and 2 hours later,normal control group and model control group, group administered ig dogwood 7g / kg adrenaline in rats with hyperglycemia rats were divided equally into three groups, fasting and 2 hours later,normal control group and model control group, group administered ig dogwood 7g / kg .
1 hour after administration, the rats of control group, physiological saline sc;modeling control group and treatment group. The rat adrenal sc 0. 25mg / kg 135 minutes after injection and blood glucose measured 135 minutes after injection and blood glucose measured .
visible dogwood antagonistic adrenergic effect of hyperglycaemia on visible dogwood antagonistic adrenergic effect of hyperglycaemia on . alloxanized hyperglycemic rats, liver glycogen and triglyceride and cholesterol in rats alloxanized hyperglycemic rats, liver glycogen and triglyceride and cholesterol in rats .
1 divided equally into three groups: normal control, another group 2 in rat sublingual ePur / kg alloxan for a physiological saline solution, wherein the set of administeredorally up to daily dose of 7g / kg 1 divided equally into three groups: normal control, another group 2 in rat sublingual ePur / kg alloxan for a physiological saline solution, wherein the set of administeredorally up to daily dose of 7g / kg . dogwood, Cornus officinalis on diabetic rats with hyperglycemia at admission (P 0. 05),increased the rat liver glycogen, but the triglyceride and cholesterol had no significant influence on
azo sulfanilamide in rats with diabetes using Wistar male rats animals stageⅠto azo sulfanilamide in rats with diabetes using Wistar male rats animals stageⅠto . 45 hours after 50 - 65 mg / kg to induce diabetes azo sulfanilamide 45 hours after 50 - 65 mg / kg to induce diabetes azo sulfanilamide .
Rehmanniae Bolus of Eight Ingredients ingredients from dry powder of the extract and the other component is made of a powder made of cornel Rehmanniae Bolus of Eight Ingredients ingredients from dry powder of the extract and the other component is made of a powder made of cornel . except for using diethyl ether extraction agent (COE) and is further separated from the other three subfractions of LDL were collected: 1 -, 2 - fr a COE, COE - rf - 3 then except for using diethyl ether extraction agent (COE) and is further separated from the other three subfractions of LDL were collected: 1 -, 2 - fr a COE, COE - rf - 3 then .
,From the COE - fr - 2 prepared in three crystalline a cod - liver oil acid, ursolic acid and 2 - a - hydroxy ursolic acid, the former two for experimental use, dogwood and Bawei Dihuang Pills of powder was 2g / kg, COE1g / kg, the COE of the three sub - fractions and cod - liver oil acid and ursolic acid were 0. 5g / kg administration method are: azo sulfanilamide and after intravenous administration of streptozotocin (lh) after po administration began, after twice a day dosing for 6 times.the last 3 hours after administration when the great cardiac vein blood was taken from the abdominal cavity to perform blood glucose measurement for the simultaneous determination of glucose in urine and animal
20 hours of water intake and urine volume 20 hours of water intake and urine volume . experiments, Ba Wei Di Huang Wan of dogwood powder and wherein the anti - diabetic effect was most pronounced, dogwood powder dosing of the animals after 20 hours of drinking is 23. 3 2. + -. 8,with the control group (46. 4. + -. 50) was extremely different (P =
blood glucose (mg / dl) and urine glucose levels (mg / 20 - hour urine) 393 respectively. The differences were 28. 7 2553 and. 205 0. + -. 1. Compared with control group (470. 0. + -. 21. 3 4733 and. 389 7. + -. 5) are obviously different from that of the former P 0. 05, P = 0.0001 Bawei Dihuang Wan powder of lowering blood glucose and urine glucose of action also learn non - obvious, while its dry extract had no effect Bawei Dihuang Wan powder of lowering blood glucose and urine glucose of action also learn non - obvious, while its dry extract had no effect .
dogwood of ether in the extraction agent,especially COE - fr - 2 is one of the strongest dogwood of ether in the extraction agent,especially COE - fr - 2 is one of the strongest . COE - fr - 2 after administration, the animals 20 hours of the water intake and urine volume were 13. 8 + / - 4 and 13. 5. + -. 9, compared with the control group (50. 0 3 2 and 36. 7 3 / 0) were very significant difference (P = 0.001, blood sugar and urine sugar content ranged between 227.70 ~ 2. + -. 25. 3 978 and. + -. 2 ~ 8 compared with the control group (403 + -. 3 36. 6 2916 and. 8 55. + -. 4), has significant difference (P 0. 05, P = 0.0001, andCOE COE - fr - l and also has important action, and while the COE COE - fr - 2 can reduce the weight of animals from the COE trend
- fr - 2 in the separation of the liver oil acid and ursolic acid, both of which can significantly reduce the number of animals 20 hours of the water intake and urine volume, but only the ursolic acid can significantly lower blood sugar and urine sugar - fr - 2 in the separation of the liver oil acid and ursolic acid, both of which can significantly reduce the number of animals 20 hours of the water intake and urine volume, but only the ursolic acid can significantly lower blood sugar and urine sugar . ursolic acid after administration, blood glucose and urine glucose content respectively 294. 2 37. + -. 2 and 1175. 249 5. + -. 2,Compared with the control (513. 2 35. + -. 4 3013 and a. 404 3. + -. 2) has a very significant difference (P 0. 0001) on the hemorheological effect in alloxan diabetic rats by ig in Cornus officinalis Sieb. et Zucc. 7g / kg, tail vein blood glucose was measured again with
40 mg / kg pentobarbital sodium anesthesia solution, heparinized blood, and whole blood viscosity 40 mg / kg pentobarbital sodium anesthesia solution, heparinized blood, and whole blood viscosity . hyperglycemic rat platelet aggregation effect of cornel 7h / kg, ig) in alloxan diabetic rats after 2 hours, 3. 8% sodium citrate (9: 1 ratio of anticoagulant,Then, Upro, preparing platelet rich and platelet poor plasma, and ADP is used as an aggregating agent is used to measure the effect on platelet aggregation
Result The group of the platelet aggregation inhibition rate was 44. 6% (P. 0001
Immune System
Male ICR mice were randomly divided into 4 groups: Control group intragastri dogwood 10. 20g / kg (water);everyday the same amount of water, the one positive group to d3, continuous 3dip cyclophosphamide 50mg / kg 24 hours after the last administration, exsanguination of the animals were sacrificed, thymus, spleen and liver is one of the so - called wet weight is calculated by taking each of the index 24 hours after the last administration, exsanguination of the animals were sacrificed, thymus, spleen and liver is one of the so - called wet weight is calculated by taking each of the index .
Cornus officinalis in mice; thymus, liver, spleen had no significant effect on Cornus officinalis in mice; thymus, liver, spleen had no significant effect on . carbon granular clearance rate of male ICR mice, dogwood, cyclophosphamide and the administration dosage and manner with the carbon granular clearance rate of male ICR mice, dogwood, cyclophosphamide and the administration dosage and manner with the .
24 hours after the last administration,The method according to the literature of thymus and spleen of the mice was calculated (K) and rectify clearance index (a) the results of different doses of cornus officinalis 24 hours after the last administration,The method according to the literature of thymus and spleen of the mice was calculated (K) and rectify clearance index (a) the results of different doses of cornus officinalis . K group was significantly higher than that of control group on serum antibodies of mice K group was significantly higher than that of control group on serum antibodies of mice .
influence on hemolysin antibody affects male NIH mice were given daily to sheep erythrocytes (SRBC) were sensitized with former 2d, intragastri FC 5. 10g / kg, positive control group were given ip cyclophosphamide 25mg / kg, each dose after 24 hours, according to the colorimetry of the sample and calculate the HC50 can be seen in table 6, cornus officinalis 10g / kg increased the serum hemolysin and immunoglobu - lin G (IgG) antibody content,Cornus officinalis Sieb. et Zucc. 5g / kg showed no significant effect on
antibody IgG Content of BALB / C mice (male or female, the cornel of the administered dose, and positive control group received an administration start to d4, continuous 2dip antibody IgG Content of BALB / C mice (male or female, the cornel of the administered dose, and positive control group received an administration start to d4, continuous 2dip . 100 mg / kg of cyclophosphamide 24 hours after the last administration, mice, and serum was separated, single diffusion assay and measured the IgG, IgG, to precipitate the ring diameter represents the different doses of cornus officinalis 100 mg / kg of cyclophosphamide 24 hours after the last administration, mice, and serum was separated, single diffusion assay and measured the IgG, IgG, to precipitate the ring diameter represents the different doses of cornus officinalis .
absorbed significantly increased the mice serum IgG content absorbed significantly increased the mice serum IgG content . SRBC - induced delayed footpad reaction; the influence of male Kunming strain mice,in this type of SRBC sensitized one day before administration, the administered dose of dogwood and 3 in the same manner, after the last antigen challenge 1h, 24h after the mice were measured on the left and right sides of the foot pad thickness difference and the difference in weight, with the result that the FC 5, 10g / kg suppressed the delayed footpad reaction to SRBC in mice SRBC - induced delayed footpad reaction; the influence of male Kunming strain mice,in this type of SRBC sensitized one day before administration, the administered dose of dogwood and 3 in the same manner, after the last antigen challenge 1h, 24h after the mice were measured on the left and right sides of the foot pad thickness difference and the difference in weight, with the result that the FC 5, 10g / kg suppressed the delayed footpad reaction to SRBC in mice .
attack before the administration of contact dermatitis induced by taking the female NIH mice, the experimental group were sacrificed after DNCB sensitization d6, intragastri dogwood 10, 20d / kg, after the last administration (6h), coated on the side of the right ear to DNCB in mice, after 12 hours. The ears to 9 mm diameter puncher laid the groundwork for an ear piece,to the right ear of the weight represents the degree of contact dermatitis, and as a result of different doses of cornus officinalis on mouse ear swelling inhibitory effect was much less than that of attack after administration on contact dermatitis induced by 56 male NIH mice were randomly divided into 7 groups. The experimental method with the literature, to the DNCB sensitization after dl0, administered after antigen challenge in different time after ig 20g / kg
cornel dogwood to attack 3 - 15 hours after dosing were markedly suppressed in the contact dermatitis induced by DNCB in mice cornel dogwood to attack 3 - 15 hours after dosing were markedly suppressed in the contact dermatitis induced by DNCB in mice . cornus officinalis glycosides in vivo, mice were immuno - suppressive effect;Ursolic acid of in vitro cultured lymphocytes can kill mice, causing the LTT, IL - 2 and LAK cells of generation capacity, but such as intraperitoneal injection of ursolic acid on mice of above indexes were obviously cornus officinalis glycosides in vivo, mice were immuno - suppressive effect;Ursolic acid of in vitro cultured lymphocytes can kill mice, causing the LTT, IL - 2 and LAK cells of generation capacity, but such as intraperitoneal injection of ursolic acid on mice of above indexes were obviously .
Antishock
The carotid artery blood pressure is taken as 1. 5 - 3. 5kg healthy rabbits were randomly divided into two groups, Group A was the control and the control group in flutamide and cascodex 2% procaine anesthesia carotid artery dissection, catheter Rm - 600 4 - channel, into ear vein 312u / (m1, kg) of heparin 2% procaine anesthesia carotid artery dissection, catheter Rm - 600 4 - channel, into ear vein 312u / (m1, kg) of heparin .
then began to slowly bled the femoral artery, blood pressure drops below 50 mmHg then began to slowly bled the femoral artery, blood pressure drops below 50 mmHg . rabbits due to metabolic re - compensation, to stop the bloodletting after the blood pressure can be automatically rebounded rabbits due to metabolic re - compensation, to stop the bloodletting after the blood pressure can be automatically rebounded .
if recovery is high, is again bled, the blood pressure is maintained at below 60 mmHg, and continuous lh,and recording the parameters of the shock value, and then to A 1g / ml subcutaneously with shallow Cornus officinalis Injection by intravenous drip, the dosing speed is 36 drops / min;in group of normal saline was given by intravenous drip if recovery is high, is again bled, the blood pressure is maintained at below 60 mmHg, and continuous lh,and recording the parameters of the shock value, and then to A 1g / ml subcutaneously with shallow Cornus officinalis Injection by intravenous drip, the dosing speed is 36 drops / min;in group of normal saline was given by intravenous drip . Cornus officinalis Injection pH was 7. 68, the physiological saline has a pH of 7. 5
30 minutes after administration were recorded, and after the parameters of the numerical value, the termination of the experiment. The results showed that the observed : by shock stage average 49. 73 + 7. 25 mmHg rises to 87 (8.64 7. 13mmhg rose 39. 43 + 9. 97mmHg;shock phase B by an average of 55. + 46 8. 57mmHg rises 68. 61 17. + -. 6 mm Hg) and an increase of 13. 15 + 12mmHg
with a significant difference, t = 8, P 0. 001 on both blood pressure and heartbeat waves affect the amplitude of the experimental group by the shock period average 1. 42 + 0. 7mm increased is 4. 03. 11, a is 2. 61 + - 0. 72mm;in group A as well as by the body age average 1. 88 + 0. 9mm is increased to 2. 35 + 0. 87mm, is 0 - 0.15, 3.57 +
3.93mm compared with that of the two groups have significant difference, t = 5.36, P
To Inhibit Inflammation
inhibition the capillary permeability induced by male Kunming mice, body weight 18 - 22g inhibition the capillary permeability induced by male Kunming mice, body weight 18 - 22g . positive ig daily aspirin 50mg / kg;Cornus officinalis ig dosage group (5, 10g / kg (crude drug for decoction of 1g / ml) for 5 days.group for the same amount of water, lh after the last administration, each mouse's tail (GDRR and TDRR) of 5% Evans blue 5ml / kg, 5min after ip0. 7% acetic acid 10 ml / kg min intervals after the mice were exsanguinated to death, with distilled water several times. The peritoneal, collecting the flushing liquid and dilute to 10ml placed lh 751 type sepectrophotometry, using colorimetric spectrophotometer at 610 nm, by absorption of the standard curve of Evans blue dye exudation, the result of the control group, aspirin group, FC 5. 0g / kg) dye exudation (ug / ml), respectively, of the 91 1. + -. 6,4. 9 + 5 (P 0. 01), 5. 3 + 2. 0 (P 0. 01), 5. 5 + / - 8 (P) + S (x, n = 10) with different doses of cornus officinalis
visible on acetic acid - induced rat peritoneal capillary permeability increase markedly inhibited by Zhentangjing at visible on acetic acid - induced rat peritoneal capillary permeability increase markedly inhibited by Zhentangjing at . inhibited xylene - induced ear swelling in mice and male Kunming mice, body weight 18 - 22g, the group administered with Fructus Corni intragastri 10. 20g / kg, 1 h after the last administration, xylene tranlplantation and donars are coated on the surface of the mouse to the right auricle and left auricle,After 2 hours the auricle so as to cut and remove ear punch having a diameter of 9 pieces, weighing
Results, dogwood 10. 20g / kg in the mice of the left and right auricle weight difference (mg) 18.6. 2 + 4. 5, 9 / 9 4. + -. 5 (P 0. 01), 11. 3 - 3 (P = 0.01), (n = 10) indicates the dogwood significantly suppressed xylene - induced ear swelling in mice and indicates the dogwood significantly suppressed xylene - induced ear swelling in mice and .
inhibition at the dose of the rat footpad swelling of male SD rats, weighed 120 - 160g, positive control group,respectively, were intragastri aspirin 50mg / kg and Fructus Corni 5g / kg, 1 hour, the right rear foot pad of Wistar rats to scl% carrageenan into fresh egg white 0.1 ml after injection every hour to micrometer calipers are measured for the degree of footpad swelling (mm), with the result that the dogwood 5g / kg for albumen swelling resulting significantly inhibited carrageenin - induced footpad swelling only at 1 hour also had a significant effect to inhibit the proliferation of granuloma formed by implanting cotton pellets in rats Male Wistar rats, weighing 150 ~ 220g were anesthetized with diethyl etherat both sides with the forelimb of each armpit sterilized cotton ball implantation 20 mg heavy one, positive control group, respectively, continuous sc Hydrocortisone 10 mg / kg ig and FC 5, 10g / kg, the rats are sacrificed by exsanguination d8, peeling of the granulation tissue, 80 c for 3 hours, and was taken for each mouse thymus, adrenal weighing also had a significant effect to inhibit the proliferation of granuloma formed by implanting cotton pellets in rats Male Wistar rats, weighing 150 ~ 220g were anesthetized with diethyl etherat both sides with the forelimb of each armpit sterilized cotton ball implantation 20 mg heavy one, positive control group, respectively, continuous sc Hydrocortisone 10 mg / kg ig and FC 5, 10g / kg, the rats are sacrificed by exsanguination d8, peeling of the granulation tissue, 80 c for 3 hours, and was taken for each mouse thymus, adrenal weighing .
It can be seen from Table 12 dogwood significantly inhibited the proliferation of granuloma formed by implanting cotton pellets in rats,The thymus and adrenal weight without significantly affecting the It can be seen from Table 12 dogwood significantly inhibited the proliferation of granuloma formed by implanting cotton pellets in rats,The thymus and adrenal weight without significantly affecting the . reduce rat adrenal ascorbic acid content of granuloma test uses the rat right adrenal gland, and the homogenate was at 2 -, 4 - dinitrophenylhydrazine colorimetric wherein ascorbate content reduce rat adrenal ascorbic acid content of granuloma test uses the rat right adrenal gland, and the homogenate was at 2 -, 4 - dinitrophenylhydrazine colorimetric wherein ascorbate content .
FC 5, 10g / kg made a rat adrenal ascorbic acid decreased the contents of the FC 5, 10g / kg made a rat adrenal ascorbic acid decreased the contents of the . - induced PGE content within tissues of male Sprague - Dawley rats, weighing 150 - 180 g - induced PGE content within tissues of male Sprague - Dawley rats, weighing 150 - 180 g .
- administered group, positive control group respectively intragastri cornus officinalis 10g / kg) or indomethacin 50 mg / kg, 30 minutes after the last administration,in each of the right rear foot pad of scl% carrageenin 0.1 ml, 3 hours later, right back foot from the ankle on the lcm at sheared to be weighed, and placed and peeling, were treated with saline soaked in lh, the supernatant liquid was 0. 15 ml 0.5 mol / L potassium hydroxide methanol solution 1ml, isomerization at 50.d egree. C. water bath for 20 min, added methanol (2 ml, measured at 251.257 and278nm. The absorbance value (A), per gram of tissue inflammation comparable absorption values represent the content of PGE, the result of cornus officinalis 10g / kg in rats and PGE induced inflammatory foot weight. No obvious effect of
Anticancer Action
healthy ascites of mice inoculated with 0.1 ml 7 - 8 days after 'liquid for cancer growth, cancer in a drop of liquid is withdrawn to a sheet of glass, and add a drop of 20 per cent of Fructus Corni (FC) decoction and one drop of eosin Tyrode's solution, under a microscope to view the death of cancer cells, such as killed cells are stained red, not the dead remain as colorless and transparent with 7 - 8 days after 'liquid for cancer growth, cancer in a drop of liquid is withdrawn to a sheet of glass, and add a drop of 20 per cent of Fructus Corni (FC) decoction and one drop of eosin Tyrode's solution, under a microscope to view the death of cancer cells, such as killed cells are stained red, not the dead remain as colorless and transparent with .
control normal cells of the salivary gland cells and testis cells control normal cells of the salivary gland cells and testis cells Experimental results show that the cornus officinalis is able to kill all the cancer cells;testis cells also have the same effect, but only a small fraction of the salivary gland cells killed
Other Action
He assumed his report, the fluidextract on anesthetized dogs have a diuretic effect, and a drop in blood pressure lowering, blood sugar of rabbits, no influence of the above - mentioned acidic liquid He assumed his report, the fluidextract on anesthetized dogs have a diuretic effect, and a drop in blood pressure lowering, blood sugar of rabbits, no influence of the above - mentioned acidic liquid ., frogs, mice, rats, rabbits and the toxicity, body weight and blood counts with no effect on the gastric mucosa of rabbits by slight congestion, but no effect on the rabbit Tenon's , frogs, mice, rats, rabbits and the toxicity, body weight and blood counts with no effect on the gastric mucosa of rabbits by slight congestion, but no effect on the rabbit Tenon's .
cornus officinalis glycosides have a very low toxicity, no hemolysis, but there are weaker and excited parasympathetic nerve of mentagrophytes, antioxidizing cornus officinalis glycosides have a very low toxicity, no hemolysis, but there are weaker and excited parasympathetic nerve of mentagrophytes, antioxidizing .
(Science)
sarcocarp and kernel decoction for acute toxicity experiment showed that the toxicity is very low, LD50 is 53. and 55 g (crude drug) / kg, LD50 of pyrenes 90.8 g (crude drug) / kg
Application Compatibility
1, for liver and kidney deficiency, vertigo, tinnitus, soreness of waist, 1, for liver and kidney deficiency, vertigo, tinnitus, soreness of waist, . with prepared rhizome of rehmannia, wolfberry fruit, dodder, eucommia bark, etc with prepared rhizome of rehmannia, wolfberry fruit, dodder, eucommia bark, etc .
2, used in spermatorrhea, enuresis, frequent micturition, and sweating more than 2, used in spermatorrhea, enuresis, frequent micturition, and sweating more than . on insufficiency of kidney - yang caused spermatorrhea, urination can be applied, often with prepared rhizome of rehmannia, dodder seed, psoralea corylifolia, equivalent with on insufficiency of kidney - yang caused spermatorrhea, urination can be applied, often with prepared rhizome of rehmannia, dodder seed, psoralea corylifolia, equivalent with .
3, via the solid product can is indicated for women deficiency, menorrhagia, prepared rhizome of rehmannia, angelica, root of herbaceous peony, etc. the compatibility of
Clinical Application
1, Liuwei Dihuang pills (Xiao Er Yao Zheng Zhi Jue ") to cure Kidney - yin deficiency, soreness and weakness of waist and knees, dizziness, tinnitus, night sweating, seminal emission, diabetes, bone - steaming tidal fever, feverish palms and soles, dry tongue, sore throats, Tooth, heel pain, and non - closure of fontanels jin infants, red tongue, 1, Liuwei Dihuang pills (Xiao Er Yao Zheng Zhi Jue ") to cure Kidney - yin deficiency, soreness and weakness of waist and knees, dizziness, tinnitus, night sweating, seminal emission, diabetes, bone - steaming tidal fever, feverish palms and soles, dry tongue, sore throats, Tooth, heel pain, and non - closure of fontanels jin infants, red tongue, . 24g is prepared from prepared rehmannia root, cornus officinalis 12g, 12g dried yam, rhizoma alismatis, cortex moutan, poria cocos wolf each 9g 24g is prepared from prepared rehmannia root, cornus officinalis 12g, 12g dried yam, rhizoma alismatis, cortex moutan, poria cocos wolf each 9g .
on honey to make pills on honey to make pills . Fang in Cornus officinalis seed, Mi astringent herb essence Fang in Cornus officinalis seed, Mi astringent herb essence .
. 2, Guchong Decoction ('s Medical Studies") is used for the treatment of weakness of spleen - qi chong channel without solid of menorrhagia or metrorrhagia 2, Guchong Decoction ('s Medical Studies") is used for the treatment of weakness of spleen - qi chong channel without solid of menorrhagia or metrorrhagia .
metrorrhagia, which is lighter in colour on Lean,indistinct white complexion, palpitation, short breath, lassitude in loin and knee, lassitude, pale tongue, thready pulse. 30g bighead atractylodes rhizome, astragalus root, 18g, 24g, 24g, 24g dogwood, white peony 12g, 12g cuttlebone, madder 9g, charcoal - brown edge 16g, gallnut 1. 5g water decocted
. Fang in Cornus officinalis and Radix Paeoniae Alba for siding with the liver and the kidney and regulating chong - ren yin and blood, which is Fang in Cornus officinalis and Radix Paeoniae Alba for siding with the liver and the kidney and regulating chong - ren yin and blood, which is .
3, Zuogui Pill ("(complete works), Maki Kaji 3, Zuogui Pill ("(complete works), Maki Kaji . yin deficiency, dizziness, hearing loss, insomnia, seminal emission, spermatorrhea, sweating, your tongue, red tongue with little coating, fine pulse yin deficiency, dizziness, hearing loss, insomnia, seminal emission, spermatorrhea, sweating, your tongue, red tongue with little coating, fine pulse .
of rehmannia glutinosa large 240g, Chinese yam, wolfberry fruit,Cornus, cyathula root, dodder seed, deglued antler glue, turtle gelatin each of rehmannia glutinosa large 240g, Chinese yam, wolfberry fruit,Cornus, cyathula root, dodder seed, deglued antler glue, turtle gelatin each . 120g with hot dilute salt or is taken together may be decocted in water 120g with hot dilute salt or is taken together may be decocted in water .
. Fang dogwood in the liver and the kidney, and astringe essence, prevent abnormal sweating is adjuvant drug and Fang dogwood in the liver and the kidney, and astringe essence, prevent abnormal sweating is adjuvant drug and .
. 2 2.
Common - Used Fang
1, Shoulder periarthritis humeroscapularis (): 1, Shoulder periarthritis humeroscapularis (): . 35 g of water - decocted twice a day for 35 g of water - decocted twice a day for .
get better, and is then reduced to 10 to 15 grams, decoct soup or tea get better, and is then reduced to 10 to 15 grams, decoct soup or tea . has good efficacy, the medicine of the 4 ~ 5 agent would kick has good efficacy, the medicine of the 4 ~ 5 agent would kick .
2, hyperhidrosis: Fructus Corni, codonopsis pilosula each 15 grams, 9 grams of schisandra chinensis water decocted 2, hyperhidrosis: Fructus Corni, codonopsis pilosula each 15 grams, 9 grams of schisandra chinensis water decocted ., , .
day for the treatment of hyperhidrosis, susceptible to cold effective day for the treatment of hyperhidrosis, susceptible to cold effective . 3, sweat, cold limbs, faint pulse, a weak constitution verging on collapse: 50 ~ 100 g, decocted in water, has better restorative and Arresting Sweating for Relieving Depletion of 3, sweat, cold limbs, faint pulse, a weak constitution verging on collapse: 50 ~ 100 g, decocted in water, has better restorative and Arresting Sweating for Relieving Depletion of .
fit such as ginseng, aconite,would have made a better fit such as ginseng, aconite,would have made a better . 4, nephrasthenia vertigo: Lai Shan Ying 20 grams, 10 grams of fructus lycii, fructus ligustri lucidi 4, nephrasthenia vertigo: Lai Shan Ying 20 grams, 10 grams of fructus lycii, fructus ligustri lucidi .
12 g is decocted in water a day for the elderly have efficacy 12 g is decocted in water a day for the elderly have efficacy . .
5, lumbago, impotence, spermatorrhea: cornus officinalis, psoralea fruit, dodder seed, cherokee rose each 12 grams, 9 grams of angelica 5, lumbago, impotence, spermatorrhea: cornus officinalis, psoralea fruit, dodder seed, cherokee rose each 12 grams, 9 grams of angelica ., , .
1 agent has the functions of reinforcing vital energy of kidney and waist, solid essence and check spermatorrhea of 1 agent has the functions of reinforcing vital energy of kidney and waist, solid essence and check spermatorrhea of . 6, dysfunctional uterine bleeding or Menorrhagia: Fructus Corni 30 grams, 30 grams of bighead atractylodes rhizome, astragalus root 15 g, 25 g calcined fossil fragments, white peony root, 15 grams, 10 grams of madder 6, dysfunctional uterine bleeding or Menorrhagia: Fructus Corni 30 grams, 30 grams of bighead atractylodes rhizome, astragalus root 15 g, 25 g calcined fossil fragments, white peony root, 15 grams, 10 grams of madder .
, , . bean agent replenishing qi and blood,Guchong Zhixue of bean agent replenishing qi and blood,Guchong Zhixue of .
7, diabetes: 15 grams, 10 grams of smoked plum, schisandra chinensis, 15g of atractylodes rhizome 10 g 7, diabetes: 15 grams, 10 grams of smoked plum, schisandra chinensis, 15g of atractylodes rhizome 10 g ., , .
1 agent have a thirst. The work 8, spontaneous perspiration and night sweat: Fructus Corni, ledebouriella root, astragalus root each 12g, decocted in water 8, spontaneous perspiration and night sweat: Fructus Corni, ledebouriella root, astragalus root each 12g, decocted in water .
9, enuresis with dogwood, raspberry, poria cocos wolf each 9 grams, 3 grams of aconite root, prepared rhizome of rehmannia, 12 g is decocted in water 9, enuresis with dogwood, raspberry, poria cocos wolf each 9 grams, 3 grams of aconite root, prepared rhizome of rehmannia, 12 g is decocted in water . 10, frequency of micturition, incontinence in the elderly: 9 grams, 6 grams of fructus schizandrae, fructus alpiniae oxyphyllae and 6 grams, Shuijian Fu 10, frequency of micturition, incontinence in the elderly: 9 grams, 6 grams of fructus schizandrae, fructus alpiniae oxyphyllae and 6 grams, Shuijian Fu .
Proved Recipe
1, five is used for the treatment of lumbago, air cooling, waist and leg weakness: Achyranthes bidentata (went to Miao), dogwood, two, three, take as the fine powder to that before eating, to warm the tune under two money 1, five is used for the treatment of lumbago, air cooling, waist and leg weakness: Achyranthes bidentata (went to Miao), dogwood, two, three, take as the fine powder to that before eating, to warm the tune under two money . ("royal") 2, tonifying yang, qi, solid essence, Zhuang Yuan: (with wine) Fructus Corni take half a kilo of meat, fruit wine (a day, half - kilo of baking), angelica root, musk, a money ("royal") 2, tonifying yang, qi, solid essence, Zhuang Yuan: (with wine) Fructus Corni take half a kilo of meat, fruit wine (a day, half - kilo of baking), angelica root, musk, a money .
on honey to make pellet, about the same size for the 81st on honey to make pellet, about the same size for the 81st . every take pills, liquor under every take pills, liquor under .
lying salt soup ("Help Long - Lived Works" the grass is Dan) 3, on the anti - beriberi into the abdomen; heartless: dried rehmannia root, cornus officinalis, 4 liang each Dioscorea, Rhizoma Alismatis, Poria cocos,two and three on each of peony root, cassia twig, aconite (cannon), each of the two on lying salt soup ("Help Long - Lived Works" the grass is Dan) 3, on the anti - beriberi into the abdomen; heartless: dried rehmannia root, cornus officinalis, 4 liang each Dioscorea, Rhizoma Alismatis, Poria cocos,two and three on each of peony root, cassia twig, aconite (cannon), each of the two on . Bawei, which occurs at the end of honey to make pills and galls, wine under fifteen pill daily, then drink the Bawei, which occurs at the end of honey to make pills and galls, wine under fifteen pill daily, then drink the .
("Synopsis" Chey CULTULRED) 4, is used for the treatment of renal and timid, aphonia, metopism, the gods, in the mesh, scraping white complexion: shiliangba prepared rhizome of rehmannia, pulp of dogwood fruit, Chinese yam and dry four money, rhizoma alismatis, cortex moutan, poria (peeling) of each of the three money ("Synopsis" Chey CULTULRED) 4, is used for the treatment of renal and timid, aphonia, metopism, the gods, in the mesh, scraping white complexion: shiliangba prepared rhizome of rehmannia, pulp of dogwood fruit, Chinese yam and dry four money, rhizoma alismatis, cortex moutan, poria (peeling) of each of the three money . on honey to make pills as large galls on honey to make pills as large galls .
empty, the water warm under the pill ( empty, the water warm under the pill (. Xiao Er Yao Zheng Zhi Jue Wan (ZBDHW); 5. the tiny water - saving, or brings wonder: cornus meat 2 ounces, or two - medicinal materials including ginseng, white until each shiliangba qian, divided the ten agent,Decocted in water
("Longtan Fang Family's secret") 6, a cool - temperate exopathic disease, serious difference after resumption, alternate attacks of chills and fever, sweating profusely.But not cold or hot, sweat - out of the pyrolysis, hot and sweating, channeling an ocular was vulnerable and verging on collapse, or dyspnea, or uncomfortable, or qi - deficiency and insufficient interest: cornus ounces (go to the nucleus), dragon's bone (2) in fine, raw oysters (2) in fine, white peony, ginseng and four outdoor stages, licorice, three money (honey) is decocted in water was vulnerable and verging on collapse, or dyspnea, or uncomfortable, or qi - deficiency and insufficient interest: cornus ounces (go to the nucleus), dragon's bone (2) in fine, raw oysters (2) in fine, white peony, ginseng and four outdoor stages, licorice, three money (honey) is decocted in water .
( (. 's Medical Studies of Laifu Decoctionon) 's Medical Studies of Laifu Decoctionon).
Discuss Literature
1, "Zhao Yuanlao: Fructus Corni, invigorating kidney and bone marrow samples of their core body temperature can acerbity Mi essence, without pressure relief of the essence, replenishing marrow is 1, "Zhao Yuanlao: Fructus Corni, invigorating kidney and bone marrow samples of their core body temperature can acerbity Mi essence, without pressure relief of the essence, replenishing marrow is . contemporaries stripped meat and abandon its nuclear, large non - ancient, so all the digging of nearly the same time, if the" materia medica "in the primary treatment, pursuant to the said main or contemporaries stripped meat and abandon its nuclear, large non - ancient, so all the digging of nearly the same time, if the" materia medica "in the primary treatment, pursuant to the said main or .
Don't have therapy, instead of the rhizome, since other Don't have therapy, instead of the rhizome, since other . 2," "cloud, small facilities with a view to its taste is sour, CULTULRED with usage of the drug, its taste is clear! 2," "cloud, small facilities with a view to its taste is sour, CULTULRED with usage of the drug, its taste is clear! .
3," Rudimentary ": this also astringent agent, which was only Tongfa Evil?Zhu cover all diseases are caused by deficiency in the lower part, with which, in order to benefit its source, the viscera, Amway, with occlusion of turning on of the stakeholder, the non - ethereal dredging medicine if he is a so - called 3," Rudimentary ": this also astringent agent, which was only Tongfa Evil?Zhu cover all diseases are caused by deficiency in the lower part, with which, in order to benefit its source, the viscera, Amway, with occlusion of turning on of the stakeholder, the non - ethereal dredging medicine if he is a so - called . 4 also, the "Herbal Classic" dogwood CGZXP by being under the evil fever, gastrointestinal pathogenic wind, cold, wind, the wind, nasal obstruction, pimples, are the main figures in two - kidney, deficiency heat, see previous 4 also, the "Herbal Classic" dogwood CGZXP by being under the evil fever, gastrointestinal pathogenic wind, cold, wind, the wind, nasal obstruction, pimples, are the main figures in two - kidney, deficiency heat, see previous .
This medicine helps Wen, Xin can be separated, the acid can be attributed to the liver, while astringing stechuenensis, wind dissipate, the heart of chills from the lower stomach, also leader of clearing a stuffy nose and pimples, heal also noted by This medicine helps Wen, Xin can be separated, the acid can be attributed to the liver, while astringing stechuenensis, wind dissipate, the heart of chills from the lower stomach, also leader of clearing a stuffy nose and pimples, heal also noted by . numbness and who, with their pungent Sanjie, rows can also supplement the temperature of the main numbness and who, with their pungent Sanjie, rows can also supplement the temperature of the main .
), It is sour and the main service,So Yi - qi and yin and strong then ), It is sour and the main service,So Yi - qi and yin and strong then . Lean Zian organs, sensory organs and nine orifice, tendons, kidneys and bladder again Zili Lean Zian organs, sensory organs and nine orifice, tendons, kidneys and bladder again Zili .
- external, deficient cold of bladder, urinary incontinence, ears of kidney, deficiency of the kidney is deafness;live opens into Liver - deficiency is the pathogenic heat in the passenger's destination - Huang;II is subjected to cold and, as a hernia in Xiaojia, a dirty patch, which is in accoed invariably Chou Yi - external, deficient cold of bladder, urinary incontinence, ears of kidney, deficiency of the kidney is deafness;live opens into Liver - deficiency is the pathogenic heat in the passenger's destination - Huang;II is subjected to cold and, as a hernia in Xiaojia, a dirty patch, which is in accoed invariably Chou Yi . 5 "," Drug Huayi ": Fructus Corni, nourishing blood, treating dizziness, tinnitus, sensation of bitterness in the tongue is dry, the surface of the cyan, sweating, shivering, as the liver and gallbladder co - good heart 5 "," Drug Huayi ": Fructus Corni, nourishing blood, treating dizziness, tinnitus, sensation of bitterness in the tongue is dry, the surface of the cyan, sweating, shivering, as the liver and gallbladder co - good heart .
is the liver's son, Unorganized is charmed by the convergence, the convergence is quiet, clean and quiet then, in order to collect the by and by, the curing due to deficiency of QI due to fright, palpitation, asthenia make - up of the mother, too, is the liver's son, Unorganized is charmed by the convergence, the convergence is quiet, clean and quiet then, in order to collect the by and by, the curing due to deficiency of QI due to fright, palpitation, asthenia make - up of the mother, too, . kidney is the mother of the liver, the kidney being averse to dryness Xirun, Si storing essence, whereby the acid can take off, aquatic, mother - of - cure, spermatorrhea and cloudy, with Guangyangdao Road, small water - flow,, foot to ache, i.e. to solidify mother s
6," materia medica "of personality:people have diarrhea, with cornus officinalis more ounces to powder and rice as the pill, she retired, serving the best moment, i.e. the sum of the meal, quit drinking it may not be a three - day diarrhea while healing cap diarrhea, deficiency of kidney qi is the dogwood to tonify the kidney and water, and that also can be used as astringent, - but the success of diarrhea, deficiency of kidney qi is the dogwood to tonify the kidney and water, and that also can be used as astringent, - but the success of .
whereas fine slip may also stop, urine may be shrinking too, three kinds of worms which may affect a whereas fine slip may also stop, urine may be shrinking too, three kinds of worms which may affect a . dogwood or suspected sex Wen, Yin - deficiency fire, but do not over consume if you dogwood or suspected sex Wen, Yin - deficiency fire, but do not over consume if you .
Cardiff fire due to yin deficiency, dogwood and why non - yin in the raw water, stopping its Long Lei Zai of deficiency - fire Cardiff fire due to yin deficiency, dogwood and why non - yin in the raw water, stopping its Long Lei Zai of deficiency - fire . dynamic has emerged from the water, its water is fire, Hu Wen then fire its water from peacefully, if not of Cornus officinalis essence - tonifying kidney - warming face instead, phellodendron bark,Anemarrhena asphodeloides Bge., weathering cold kidney, my fear of water and the more dry by the fire, dampness, dryness and cold curing kidney while "fire", the more we tend to lower its abortion on the hatred of the spleen and lung, spleen and lung and two bad, people are so angry?
dogwood Zhengzhi yin and stirring of internal medicine, he does not suspect its Warm but instead to a large fire on the dogwood Zhengzhi yin and stirring of internal medicine, he does not suspect its Warm but instead to a large fire on the . 7, Ben Jing Feng Yuan ": Detailed sweating, the sweat is false 7, Ben Jing Feng Yuan ": Detailed sweating, the sweat is false .
in their acid charge and, well, the more understanding and then in their acid charge and, well, the more understanding and then . Zhong Jing CULTULRED used by Shenqi benefit cap, the sealing degree of possession, that liver - Yin, and then to disperse the stagnated Liver - Qi, and Yi and Kui are derived from homologous also Zhong Jing CULTULRED used by Shenqi benefit cap, the sealing degree of possession, that liver - Yin, and then to disperse the stagnated Liver - Qi, and Yi and Kui are derived from homologous also .
8," Xue Zhong Zhong Can Xi Lu: Cornel, a large convergence of invigorating vitality, refreshing oneself, astringent or styptic treatment for spondylolisthesis 8," Xue Zhong Zhong Can Xi Lu: Cornel, a large convergence of invigorating vitality, refreshing oneself, astringent or styptic treatment for spondylolisthesis . Astringent among both coherent, Man, and Lee said it is nine,circulation of blood, deficiency of the liver to treat spontaneous sweating, and pain in the hypochondrium pain Liver deficiency, deficiency of the liver to inhibit wind, and the convergence and convergence of righteousness rather than evil, and other acid - astringing medicine differently, is to "This after" is called its numbness and also its nucleus with Astringent among both coherent, Man, and Lee said it is nine,circulation of blood, deficiency of the liver to treat spontaneous sweating, and pain in the hypochondrium pain Liver deficiency, deficiency of the liver to inhibit wind, and the convergence and convergence of righteousness rather than evil, and other acid - astringing medicine differently, is to "This after" is called its numbness and also its nucleus with .
In the book of the opposite sex, when that core to near - net In the book of the opposite sex, when that core to near - net . read the medical report in what is in the nucleus to the taste, of a Master and convergence are taken, the constant makes the dysuria, vertebral breaking taste of, there's some astringent fruit, said trusted or read the medical report in what is in the nucleus to the taste, of a Master and convergence are taken, the constant makes the dysuria, vertebral breaking taste of, there's some astringent fruit, said trusted or .
mortals for vitality, are in the hand with a liver mortals for vitality, are in the hand with a liver . Leonesa imaginary pole, which is first driven by liver, liver - wind, i.e. the Genki verging on collapse of the liver and gallbladder and also another
, zang - fu organs dependent, Shaoyang Gall), there is the main disease of chills and fever;Jueyin Liver is , zang - fu organs dependent, Shaoyang Gall), there is the main disease of chills and fever;Jueyin Liver is . imaginary pole also alternate attacks of chills and fever, chills and sweating so much imaginary pole also alternate attacks of chills and fever, chills and sweating so much .
cornus can sweat cornus can sweat . again is good at nourishing liver, is liver imaginary pole and the vitality of the subjects taken, the most foolish again is good at nourishing liver, is liver imaginary pole and the vitality of the subjects taken, the most foolish .
Moun tains, a disease of the ability of originality, and the detailed view "Shen Nong's Herbal Classic" dogwood Shemer to cold, heat, cold, heat, and which, in the main, i.e., the liver via the polar nature of cold relations also ": the main evil heart under cold, warm, cold, dampness, Sanchong to ": the main evil heart under cold, warm, cold, dampness, Sanchong to .
" preparing from Lei Gongs Treatise On ": qi zhuang, secretary precision " preparing from Lei Gongs Treatise On ": qi zhuang, secretary precision ." Bielu ": gastrointestinal pathogenic wind, cold and heat and mass in the hernia, head wind, the local atmosphere to refuel, stuffy nose, and eyes, deafness, pimples, warm, under gas, sweating, strong yin, Yijing,Ann five zang - organs, sensory organs and nine orifice, small convenience, eyesight, strength " Bielu ": gastrointestinal pathogenic wind, cold and heat and mass in the hernia, head wind, the local atmosphere to refuel, stuffy nose, and eyes, deafness, pimples, warm, under gas, sweating, strong yin, Yijing,Ann five zang - organs, sensory organs and nine orifice, small convenience, eyesight, strength .
9, On Medicine Property: treat bone pain, stop months of adventitious water, tonifying Qi, strengthening Yang, essence, tinnitus therapy, in addition to the surface of the sore, the main effect of induce sweat, urine is not stop - and - three - year - old festival 9, On Medicine Property: treat bone pain, stop months of adventitious water, tonifying Qi, strengthening Yang, essence, tinnitus therapy, in addition to the surface of the sore, the main effect of induce sweat, urine is not stop - and - three - year - old festival . 10, "Materia Medica": warming waist and knees, dirty water, in addition to all the winds, all the gas, and town, and is used for the treatment of wine 10, "Materia Medica": warming waist and knees, dirty water, in addition to all the winds, all the gas, and town, and is used for the treatment of wine .
11, a "pearl sac": Warming Liver 11, a "pearl sac": Warming Liver . 12, Ben Cao to original, ": stopping diarrhea, fever and sweating 12, Ben Cao to original, ": stopping diarrhea, fever and sweating .
guilty guilty.
Identification Of Medicinal Materials
Trait Identification
fleshy pericarp crimple rupture, incomplete, or is formed as a flat cylindrical, ca. 1 cm, a width of about 0.5 cm new surface is purple, the older the see is mostly purple - black, lustrous, stalks at base sometimes visible marks, at its end a circular Calyx of trace new surface is purple, the older the see is mostly purple - black, lustrous, stalks at base sometimes visible marks, at its end a circular Calyx of trace .
. Quality soft, not brittle, odorless, sour and astringent and bitter to Quality soft, not brittle, odorless, sour and astringent and bitter to .
seedless flesh of hypertrophy, the colour red in order to moisten the prefered seedless flesh of hypertrophy, the colour red in order to moisten the prefered .
Microscopic Identification
cross - section at the level of flesh: the exocarp is slightly flattened in one column of epidermal cells, thick cuticle cross - section at the level of flesh: the exocarp is slightly flattened in one column of epidermal cells, thick cuticle . mesocarp is wide, a plurality of columns of parenchyma cells, the sizes of the cells of color which are dark brown, nearly 8 vascular bundles at the inside of the ring rows mesocarp is wide, a plurality of columns of parenchyma cells, the sizes of the cells of color which are dark brown, nearly 8 vascular bundles at the inside of the ring rows .
stalk near at a cross - sectional view of a surface often have stone cells and fiber bundle stalk near at a cross - sectional view of a surface often have stone cells and fiber bundle .
Chemical Identification Of Traditional Chinese Medicine
Thin Layer Chromatography: Prepare 1g of powdered medicinal, adding ether refluxing 2 hours, and then with petroleum ether (60 - 90 c) refluxing and extracting for 4 hours and the extract was recovered after the solvent is chloroform - absolute alcohol (1: 1) mixed solvent for dissolving the spotting Thin Layer Chromatography: Prepare 1g of powdered medicinal, adding ether refluxing 2 hours, and then with petroleum ether (60 - 90 c) refluxing and extracting for 4 hours and the extract was recovered after the solvent is chloroform - absolute alcohol (1: 1) mixed solvent for dissolving the spotting . the another group of ursolic acid control, with chloroform - EtOH (1: 1) mixed solvent to obtain a control solution to the two solutions were respectively spotted on the reverse the same octadecylsilane - bonded silica gel, using cyclohexane - chloroform - ethyl acetate (20: 5: 8), the plate was dried, 10% sulfuric acid ethanol spray reagent, and drying at 110.d egree. C. for 5 minutes, the test sample solution chromatogram at the same position,There is the same as the amaranth spot
the cultivation of medicinal plants on biological characteristics in warm and humid climate, it is better to select the light the cultivation of medicinal plants on biological characteristics in warm and humid climate, it is better to select the light . .
prefers fertile soil, deep soil, well - drained sandy loam or loam soil cultivation prefers fertile soil, deep soil, well - drained sandy loam or loam soil cultivation .
Cultivation Techniques
Biological Characteristics
The reproduction by seeds, layering and cutting propagation The reproduction by seeds, layering and cutting propagation . seed propagation;autumn fruit maturity, harvesting a large, red color of the fruit seed, stripped of flesh, the ethnic cleansing of the seeds, with sand layered cellar, overwintering and seedling transplanting method of pregermination seed propagation;autumn fruit maturity, harvesting a large, red color of the fruit seed, stripped of flesh, the ethnic cleansing of the seeds, with sand layered cellar, overwintering and seedling transplanting method of pregermination .
: in March - April spring sowing, row spacing 30cm according to the opening of the Han people, after sowing grass covered with soil, watering, keep the soil moist, after emergence, the removal of the cover grass, weeding, loosening soil, fertilization, the seedling height of 30 - 60cm, transplanting, planting, when row spacing of 2m x 2m : in March - April spring sowing, row spacing 30cm according to the opening of the Han people, after sowing grass covered with soil, watering, keep the soil moist, after emergence, the removal of the cover grass, weeding, loosening soil, fertilization, the seedling height of 30 - 60cm, transplanting, planting, when row spacing of 2m x 2m . .
Live planted with Yang - ZiTime Point - Open Method: cultivating in a row - by - 2m x 2m spacing, fertilizing, thinning each dibble seeding was 3 ~ 4 capsules, covered with soil 1 - 2cm Live planted with Yang - ZiTime Point - Open Method: cultivating in a row - by - 2m x 2m spacing, fertilizing, thinning each dibble seeding was 3 ~ 4 capsules, covered with soil 1 - 2cm . layering: harvested in autumn,ground - level 2, and 3 years old branches are bent to the ground, at or near the ground surface is cut through the xylem to shoots 1 / 3 and being buried in soil overlying a 15cm thick layer of sandy loam layering: harvested in autumn,ground - level 2, and 3 years old branches are bent to the ground, at or near the ground surface is cut through the xylem to shoots 1 / 3 and being buried in soil overlying a 15cm thick layer of sandy loam .
2 in winter or the 3rd year in the spring of the root bead has been long and maternal separation on 2 in winter or the 3rd year in the spring of the root bead has been long and maternal separation on . graft cuttings: around mid - May, late in the one - year - old mother clipping branches, lignification of shoots Cut 15 - 20cm of the spike strip, sand bed and a row spacing in x 8cm cuttings, cap insulation film, on the light - shielding shade, watering, weeding, fertilizing in early spring the following year graft cuttings: around mid - May, late in the one - year - old mother clipping branches, lignification of shoots Cut 15 - 20cm of the spike strip, sand bed and a row spacing in x 8cm cuttings, cap insulation film, on the light - shielding shade, watering, weeding, fertilizing in early spring the following year .
Field Management
a year after planting and weeding should be 4 - 5 times;5, and 6 months increased the superphosphate, promote and increase the fruit setting rate of winter wax applying fertilizer, also can result in differences in the size of the balance in the summer of hilling a year after planting and weeding should be 4 - 5 times;5, and 6 months increased the superphosphate, promote and increase the fruit setting rate of winter wax applying fertilizer, also can result in differences in the size of the balance in the summer of hilling . 1, 1, .
saplings to prevent lodging was about 40 - 60 cm, between December and February and hit the top, and 3 - 4 branch, branch selection can be carry out on - the - job - 3, four sub - branches, forming a natural shape systems saplings to prevent lodging was about 40 - 60 cm, between December and February and hit the top, and 3 - 4 branch, branch selection can be carry out on - the - job - 3, four sub - branches, forming a natural shape systems . saplings to shaping, trimming and supplemented with saplings to shaping, trimming and supplemented with .
because of the dogwood long, both in the short fruit to bud tip results in various branches may not be shorter than a truncated because of the dogwood long, both in the short fruit to bud tip results in various branches may not be shorter than a truncated . adult tree in spring and autumn cropping, adjusting the contradiction between the growth and fruiting, fruiting update group, reserved growing dendrites, a short section, adult tree in spring and autumn cropping, adjusting the contradiction between the growth and fruiting, fruiting update group, reserved growing dendrites, a short section,.
promote ramification promote ramification.
Pest Control
Diseases with gray plaster disease, mature plants and is easy to occur, by a mealy bug infestation, became ill in 1: 1: 100 Bordeaux protect Diseases with gray plaster disease, mature plants and is easy to occur, by a mealy bug infestation, became ill in 1: 1: 100 Bordeaux protect . anthracnose, in early June and the onset of infected fruits, prevention methods and see gray plaster disease in cheng anthracnose, in early June and the onset of infected fruits, prevention methods and see gray plaster disease in cheng .
powdery mildew, and damage of the plants, at the initial injection of 50% thiophanate methy 1 000 times powdery mildew, and damage of the plants, at the initial injection of 50% thiophanate methy 1 000 times . pests damaging fruit borer pest feed on fruit, in the peak period of eclosion and spraying 2. 5% Decamethrin and 5 000 times;wooden mask inchworm, Lei bagworm infestation
Plant Culture
Fructus Corni in this name first appeared in "Fructus Corni in this name first appeared in ". in folk, Cornus officinalis on the origin of the name is still a legend in folk, Cornus officinalis on the origin of the name is still a legend .
Zhao in the Warring States Period (475 - 221 BC), Wang According to the legend of cervical vertebra, neck pain, a physician with a liftoff a fruit decoction to Zhao Wang within the administration, and soon made Wang Zhao relieves the indisposition Zhao in the Warring States Period (475 - 221 BC), Wang According to the legend of cervical vertebra, neck pain, a physician with a liftoff a fruit decoction to Zhao Wang within the administration, and soon made Wang Zhao relieves the indisposition . while Wang Zhu Houzhao asked his physician for a panacea, the answer is the Zhu royal family were of cornus officinalis, if being taken for a long time, not only can cure the cervical pain, it is also possible, and improving the king to hear while Wang Zhu Houzhao asked his physician for a panacea, the answer is the Zhu royal family were of cornus officinalis, if being taken for a long time, not only can cure the cervical pain, it is also possible, and improving the king to hear .
after the wedding, the major species of medicinal herbs. The Zhu, an Archiater in recognition of achievements, it will be renamed Shan Zhu, fructus Corni, Later on, people Now Shan Zhu Yu wrote of dogwood, Zhu, an Archiater in recognition of achievements, it will be renamed Shan Zhu, fructus Corni, Later on, people Now Shan Zhu Yu wrote of dogwood,.
gradually and survive from the ancient worship of Cornus officinalis, charmingly, the legendary King of Chu in the Warring States Period (475 - 221 BC), the Princess was carrying a spray of dogwood and jewelry, to Chongyang day scenic, the cornel twigs, cornel, drinking cornel wine, dogwood and chanting poems, the best of pleasure feed upon Le gradually and survive from the ancient worship of Cornus officinalis, charmingly, the legendary King of Chu in the Warring States Period (475 - 221 BC), the Princess was carrying a spray of dogwood and jewelry, to Chongyang day scenic, the cornel twigs, cornel, drinking cornel wine, dogwood and chanting poems, the best of pleasure feed upon Le . Wen people together out to Chongyang Mastixia climbing tours, especially in the Tang Dynasty, Bai Juyi, Du Fu, Han Shan, such poets were singing and this custom of wearing cornel on the poem, while the most popular account of Wang Wei is the "9th Yidong see brother", the poem said: "THE ELDER DAY brothers climb Department Biancha Zhuyu less a person" Wen people together out to Chongyang Mastixia climbing tours, especially in the Tang Dynasty, Bai Juyi, Du Fu, Han Shan, such poets were singing and this custom of wearing cornel on the poem, while the most popular account of Wang Wei is the "9th Yidong see brother", the poem said: "THE ELDER DAY brothers climb Department Biancha Zhuyu less a person" .
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