魏海明:博士生導師。籍貫:安徽。山東大學醫學院免疫學專業博士畢業。現為中國科學技術大學生命科學實驗中心常務副主任,中國科學技術大學生命學院實驗動物中心主任,中國免疫學會英文會刊Cellular&MolecularImmunology編輯部主任。中國免疫學會終身會員、理事,中國免疫學會青年學術委員會委員,中國抗癌協會腫瘤生物治療專業委員會委員,安徽省免疫學會副理事長。2002年以來為首承擔參加了6項科研項目,其中國家863課題2項,國家973課題1項,國家自然科學基金項目2項,國家傑出青年科學基金B類1項(國內負責人),安徽省人才培養及科研帶頭人專項資金1項。近5年發表SCI論文25篇。
主要發表論文
HaimingWei,JianZhang,WeiXiao,JinboFeng,RuiSun,andZhigangTian.InvolvementofHumannaturalkiller(NK)cellsinasthmapathogenesis:NK2cellsintype-twocytokinepredominance.JAllergyClinImmunol.2005Apr;115(4):841-7HaimingWei,XiaodongZheng,DermingLou,LiangZhang,RuijunZhang,RuiSun,ZhigangTian.Tumor-inducedsuppressionofinterferonproductionandenhancement ofinterleukin-10productionbynaturalkiller(NK)cells:paralleledtoCD4+Tcells.MolecularImmunology;2005May;42(9):1023-31
ZhangB,WeiHM,ZhengXD,TianZG.Syntheticshortpeptides,mimickingMICAandtargetingatNKG2Dreceptors,inhibitthefunctionofhumanNKcells:implicationintherapyofautoimmuneliverinjury.Peptides;2005Mar;26(3):405-12.
WeiH,SunR,XiaoW,FengJ,ZhenC,XuX,TianZ.TraditionalChinesemedicineAstragalusreversespredominanceofTh2cytokinesandtheirup-streamtranscriptfactorsinlungcancerpatients.OncolRep.2003;10(5):1507-12
ZhangJ,SunR,WeiHM,TianZ.Antitumoreffectsofrecombinanthumanprolactininhumanadenocarcinoma-bearingSCIDmicewithhumanNKcellxenograft.IntImmunopharmacol.2005Feb;5(2):417-25.
DongZJ,WeiHM,SunR,ZhiqiangHou,GaoB,TianZG.InvolvementofnaturalkillercellsinPolyIC-inducedliverinjury.Journalofhepatology;2004;41(6):966-973(IF=5.3)
SunR,WeiH,ZhangJ,TianZ.Theeffectsofnaturalkiller-celldepletiononexvivoexpansionofhematopoieticprogenitorcellsfromumbilicalcordblood.Haematologica.2003;88(5):561-9.
LiuW,WeiH,LiangS,ZhangJ,SunR,TianZ.Abalancedexpressionoftwochainsofheterodimerprotein,thehumaninterleukin-12,improveshigh-levelexpressionoftheproteininCHOcells.BiochemBiophysResCommun.2004;313(2):287-93.
LiangS,WeiH,SunR,TianZ.IFNalpharegulatesNKcellcytotoxicitythroughSTAT1pathway.Cytokine.2003;23(6):190-9.
ChenY,WeiH,GaoB,HuZ,ZhengS,TianZ.ActivationandfunctionofhepaticNKcellsinhepatitisBinfection:anunderinvestigatedinnateimmuneresponse.JViralHepat.2005Jan;12(1):38-45.
WuP,WeiH,ZhangC,ZhangJ,TianZ.RegulationofNKcellactivationbystimulatoryandinhibitoryreceptorsintumorescapefrominnateimmunity.FrontBiosci.2005Sep1;10:3132-42.
SunR,WeiH,ZhangJ,LiA,ZhangW,TianZ.Recombinanthumanprolactinimprovesantitumoreffectsofmurinenaturalkillercellsinvitroandinvivo.Neuroimmunomodulation.2002-2003;10(3):169-76.