內容簡介
0世紀70年代發現核磁共振（MRI）以來，其套用在近30年間得到飛速發展，目前它已成為現代社會無傷害性醫學成像技術中最為重要的技術之一。隨著神經科學的迅速發展，20世紀90年代初功能性核磁共振（fMRI）被引入，並成為當今探索大腦活動最有價值的工具之一。本書詳細介紹了核磁共振、功能性核磁共振的成像原理及套用方法。
成像的速度是核磁共振重要的衡量指標，Multiband（MB）成像是前沿的高時間解析度成像技術，可用於同時採集多層圖像。本書將介紹Multiband成像原理及其3個套用，具體包括靜態功能性核磁共振（resting-state fMRI）、軀體感覺區功能性核磁共振（somatosensory fMRI）和磁共振動脈自旋標（ASL）。
圖書目錄
Contents
Abstract
Acknowledgements
1Introduction
1.1Comparison between the MRI and others
1.2Overview of the book
2Nuclear magnetic resonance and magnetic resonance imaging
2.1NMR
2.1.1Introduction
2.1.2Nuclei and spin, energy levels
2.1.3Spins in magnetic eld
2.1.4Boltzmann statistics
2.1.5Rotating frame
2.1.6Relaxation
2.1.7Bloch equation
2.1.8Chemical shift
2.2MRI
2.2.1Introduction
2.2.2Gradients
2.2.3Slice selection
2.2.4Spatial encoding
2.2.5k-space
2.2.6Gradient echo imaging
2.2.7Spin echo imaging
2.2.8Echo planar imaging
2.2.9Turbo spin echo imaging
2.2.10GRASE
2.2.11Parallel imaging
2.2.12Simulation of matrix inversion
2.3Hardware
2.3.1Overview
2.3.2Main magnet
2.3.3Shim coils
2.3.4Gradient coils
2.3.5RF system
Bibliography
3Functional magnetic resonance imaging
3.1Introduction
3.2Cerebral cortex
3.2.1Somatosensory cortex
3.2.2Motor cortex
3.2.3Visual cortex
3.3BOLD contrast
3.4fMRI data acquisition
3.5Paradigm
3.6Data analysis
3.6.1Preprocessing
3.6.2Statistical analysis
3.7Cortical flattening
3.8Resting state
3.9Perfusion imaging
3.10Conclusion
Bibliography
4A comparison of resting state functional connectivity
using fast imaging: 2D GEEPI, 3D GEEPI and 3D PRESTO
4.1Introduction
4.1.1Brain networks
4.1.2Default mode network （DMN）
4.1.3Sensorimotor network
4.1.4Visual network
4.1.5Dorsal attention network
4.2Overview of fast imaging sequences
4.2.1Echo planar imaging
4.2.2PRESTO
4.3Methods
4.3.1Data acquisition
4.3.2Data analysis
4.4Results
4.4.1No physiological noise correction
4.4.2Post physiological correction
4.5Discussion
4.6Conclusion
Bibliography
5Implementation and application of multiband echo planar
imaging in conjunction with SENSE
5.1Introduction
5.2Multiband imaging
5.2.1Introduction
5.2.2Multiband RF pulses
5.2.3Optimization
5.2.4Reconstruction
5.3Implementation
5.4Applications
5.4.1Resting state fMRI
5.4.2Somatotopic mapping of both primary and secondary
somatosensory cortex
5.4.3Multiband DABS ASL
5.5Conclusion
Bibliography
6Orientation mapping at ultra-high field
6.1Visual cortex
6.2Retinotopic organization
6.3Orientation column organization
6.4Introduction to the study
6.5Methods
6.5.1Stimuli and paradigm
6.5.2fMRI data acquisition
6.5.3Pre-processing
6.5.4Data analysis
6.6Results
6.7Discussion
6.8Conclusion
Bibliography
Abbreviations
Index
