個人履歷
2013年6月畢業於中國科學院天津工業生物技術研究所工業酶國家工程實驗室,獲碩士學位;
2016年7月畢業於中國科學院青島生物能源與過程研究所,獲博士學位;
2016年9月起任教於青島農業大學 化學與藥學院,教授,碩士生導師。
研究方向
生物納米材料的設計:納米酶、仿生納米材料、生物無機雜化納米材料;
生物醫學感測平台的構建:致病菌、癌細胞、蛋白標誌物、關鍵生物分子的檢測與疾病診斷;
生物納米材料在農業中的套用:農業感測檢測平台的構建、農藥降解、新型生物納米農藥的研發
表面展示技術:微生物表面展示、噬菌體表面展示、特異性生物探針淘選;
酶工程:酶的基因工程改造、人工模擬酶、新型酶感測器。
主講課程
研究生課程:《生物化學工程》
本科生課程:《分析化學》、《基礎化學實驗》、《食品化學與分析》
科研代表作
[1] Lei Han, Haijiao Zhang, Daoyuan Chen, Feng Li*. Protein-Directed Metal Oxide Nanoflakes with Tandem Enzyme-Like Characteristics: Colorimetric Glucose Sensing Based on One-Pot Enzyme-Free Cascade Catalysis. Advanced Functional Materials. 2018. 28. 1800018.(影響因子13.325)
[2] Haijiao Zhang, Xin Liang, Lei Han*, Feng Li*. “Non-Naked” Gold with Glucose Oxidase-Like Activity: A Nanozyme for Tandem Catalysis. Small. 2018. 14(44). 1803256.(影響因子9.598)
[3] Lei Han, Pei Liu, Haijiao Zhang, Feng Li*, and Aihua Liu, Phage Capsid Protein-Directed MnO2 Nanosheets with Peroxidase-Like Activity for Spectrometric Biosensing and Evaluation of Antioxidant Behaviour, Chemical Communications. 2017. 53(37). 5216–5219. (Nature指數期刊)
[4] Lei Han, Hongqi Xia, Long Yin, Valery A. Petrenko, Aihua Liu*. Selected landscape phage probe as selective recognition interface for sensitive total prostate-specific antigen immunosensor. Biosensors and Bioelectronics. 2018. 106. 1–6.(影響因子8.173)
[5] Lei Han, Dapeng Yang*, and Aihua Liu*, Leaf-Templated Synthesis of 3D Hierarchical Porous Cobalt Oxide Nanostructure as Direct Electrochemical Biosensing Interface with Enhanced Electrocatalysis, Biosensors and Bioelectronics. 2015, 63, 145−152.
[6] Lei Han, Aihua Liu*. Novel Cell–Inorganic Hybrid Catalytic Interfaces with Enhanced Enzymatic Activity and Stability for Sensitive Biosensing of Paraoxon. ACS Applied Materials & Interfaces. 2017. 9(8). 6894–6901.(影響因子8.097)
[7] Lei Han, Changxu Shao, Bo liang, and Aihua Liu*, Genetically Engineered Phage-Templated MnO2 Nanowires: Synthesis and Their Application in Electrochemical Glucose Biosensor Operated at Neutral pH Condition, ACS Applied Materials & Interfaces. 2016, 8, 13768–13776.
[8] Lei Han, Cuncheng Li, Tao Zhang, Qiaolin Lang, and Aihua Liu*, Au@Ag Heterogeneous Nanorods as Nanozyme Interfaces with Peroxidase-Like Activity and Their Application for One-Pot Analysis of Glucose at Nearly Neutral pH, ACS Applied Materials & Interfaces. 2015, 7, 14463–14470.
[9] Lei Han, Lingxing Zeng, Mingdeng Wei*, ChangMing Li, and Aihua Liu*, V2O3-Ordered Mesoporous Carbon Composite with Novel Peroxidase-Like Activity towards Glucose Colorimetric Assay, Nanoscale. 2015, 7, 11678–11685.
[10] Yanfang Zhao, Chao Chang, PanPan Gai, Lei Han*, Feng Li*, Bo Li. One-step synthesis of fluorescent organic nanoparticles: the application to label-free ratiometric fluorescent pH sensor. Sensors and Actuators B: Chemical. 2018. 273. 1479−1486.