董琳:女,四川大學華西藥學院 教授(博士生導師)
簡歷
1994-1998 鄭州大學化學系,化學專業,理學學士
2001-2006 中國科學院成都有機化學研究所,有機化學專業,碩博連讀,師從龔流柱教授
2006-2009 澳大利亞昆士蘭大學化學系,博士後,師從Craig M. Williams教授
2009-2011 新加坡科技研究局化學與工程科學研究院,研究科學家,師從著名化學家K. C. Nicolaou 教授
2011-至今 四川大學華西藥學院,副教授
獲獎情況
1、2012年 四川省“青年百人計畫”海外高層次引進人才
2、2012年 四川大學優秀青年骨幹教師獎勵
研究方向
1、 有機合成方法學研究
2、天然產物與藥物合成
科研項目及成果
1、國家自然科學基金青年基金:“3位季碳手性中心吲哚類天然產物及藥物的全合成研究”
2013-2015,項目負責人
發表論文
2011 年以後
[1] Dong, L.*; Qu, C.-H.; Huang, J.-R.; Zhang, W.; Zhang, Q.-R.; Deng, J.-G. “Rhodium-catalyzed Spirocyclic Sultam Synthesis by [3+2] Annulation with CyclicN-Sulfonyl Ketimines and Alkynes”,Chem. Eur. J. 2013,DOI: 10.1002/chem.201303372.
[2] Dong, L.*; Huang, J.-R.; Qu, C.-H.; Zhang, Q.-R.; Zhang, W.; Han, B.; Peng, C.* “Rhodium(III)-catalyzed vinylic sp2 C–H bond functionalization: efficient synthesis of pyrido[1,2-α]-benzimidazoles and imidazo[1,2-α]pyridines”,Org. Biomol. Chem. 2013,11, 6142–6149.
[3] Huang, J.-R.; Zhang, Q.-R.; Qu, C.-H.; Sun, X.-H.; Dong, L.* Chen. Y.-C.* “Rhodium(III)-Catalyzed Direct Selective C(5)-H Oxidative Annulations of 2-Substituted Imidazoles and Alkynes by Double C-H Activation”,Org. Lett. 2013,15, 1878-1881.
[4] Huang, J.-R.; Dong, L.*; Han, B.; Peng, C.*; Chen. Y.-C.* “Synthesis of Aza-Fused Polycyclic Quinolines via Double C-H Bond Activations”,Chem. Eur. J. 2012,18, 8896-8898.
2011年以前
[1] Dong, L.; Deng, L.-J.; Lim, Y.-W.; Leung, G. Y.-C.; Chen, D. Y.-K.* “Synthesis of Advanced Maoecrystal V Core Structure”,Chem. Eur. J. 2011,17, 5778-5781.
[2] Nicolaou, K.-C.*; Dong, L.; Deng, L.-J.; Talbota, A. C.; Chen, D. Y.-K. “Synthesis of functionalized maoecrystal V core structures”,Chem. Commun. 2010,46, 70-72.
[3] Dong, L.; Schill, H.; Grange, R. L.; Porzelle, A.; Johns, J. P.; Parsons, P. G.; Gordon, V. A.; Reddell, P. W.; Williams, C. M.* “Anticancer Agents from the Australian Tropical Rainforest: Spiroacetals EBC-23, 24, 25, 72, 73, 75 and 76”,Chem. Eur. J. 2009,15, 11307-11318.
[4] Dong, L.; Gordon, V. A.; Grange, R. L.; Johns, J.; Parsons, P. G.; Porzelle, A.; Reddell, P.; Schill, H.; Williams, C. M.* “Synthesis of ent-EBC-23”,Highlight in Synfacts, 2009, 468.
[5] Dong, L.; Gordon, V. A.; Grange, R. L.; Johns, J.; Parsons, P. G.; Porzelle, A.; Reddell, P.; Schill, H.; Williams, C. M.* “Structure and Absolute Stereochemistry of the Anticancer Agent EBC-23 from the Australian Rainforest", J. Am. Chem. Soc. 2008,130, 15262-15263.
[6] Dong, L.; Xu, Y.-J.; Gong, L.-Z.* “Rhodium-Catalyzed Asymmetric Nitroallylation of Arylmetallics with Cyclic Nitroallyl Acetates and Applications in Organic Synthesis”,Eur.J. Org. Chem. 2006, 4093-4105.
[7] Dong, L.; Xu, Y.-J.; Cun, L.-F.; Cui, X.; Mi, A.-Q.; Jiang, Y.-Z.; Gong, L.-Z.* “Asymmetric Nitroallylation of Arylboronic Acids with Nitroallyl Acetates Catalyzed by Chiral Rhodium Complexes and Its Application in a Concise Total Synthesis of Optically Pure (+)-g-Lycorane”,Org. Lett. 2005,7, 4285-4288.
[8] Dong, L.; Xu, Y.-J.; Gong, L.-Z.*; Mi,A.-Q.; Jiang, Y.-Z. “Conjugate Additions ofα,β-Unsaturated Ketones with Arylzinc Species That Form in Situ from Diethylzinc and Arylboronic Acids”,Synthesis, 2004,7, 1057.