研究方向
● 癌症化學預防的動物模型研究;
● 癌症發生的易感基因研究
發表論文
[1] You MS,Rouggly LC, You M, Wang Y*. Mousemodels of lung squamous cell carcinomas. Cancer Metastasis Rev. 2013Jun;32(1-2):77-82.
[2] Wang Y, Yao R, Gao S, Wen W, Du Y,Szabo E, Hu M, Lubet RA, You M. Chemopreventive effect of a mixture of ChineseHerbs (antitumor B) on chemically induced oral carcinogenesis. Mol Carcinog.2013 Jan;52(1):49-56.
[3] Pan J,Zhang Q, Li K, Liu Q, Wang Y, You M.Chemoprevention of lung squamous cell carcinoma by ginseng. Cancer Prev Res(Phila). 2013 Jun;6(6):530-9.
[4] Zhang Q,Pan J, Wang Y, Lubet R, You M.Beetroot red (betanin) inhibits vinyl carbamate- and benzo(a)pyrene-inducedlung tumorigenesis through apoptosis. Mol Carcinog. 2013 Sep;52(9):686-91.
[5] Dragnev K,You M, Wang Y, Lubet R. Lung cancerchemoprevention: difficulties, promise and potential agents?Expert OpinInvestig Drugs. 2013 Jan;22(1):35-47.
[6] Xiong D, LiG, Li K, Xu Q, Pan Z, Ding F, Vedell P, Liu P, Cui P, Hua X, Jiang H, Yin Y,Zhu Z, Li X, Zhang B, Ma D, Wang Y,You M. Exome sequencing identifies MXRA5 as a novel cancer gene frequentlymutated in non-small cell lung carcinoma from Chinese patients. Carcinogenesis.2012 Sep;33(9):1797-805.
[7] Zhang Q,Pan J, North PE, Yang S, Lubet RA, WangY, You M. Aerosolized 3-bromopyruvate inhibits lung tumorigenesis withoutcausing liver toxicity. Cancer Prev Res(Phila). 2012 May;5(5):717-25.
[8] PengyuanLiu, Hongbo Liu, Yan Lu, Weidong Wen, Dongmei Jia, Yian Wang, and Ming You. Genome-wide association and fine mappingof genetic loci predisposing to colon carcinogenesis in mice. Mol Cancer Res2012;10:66-74.
[9] James MA,Wen W, Wang Y, Byers LA, Heymach JV,Coombes KR, Girard L, Minna J, You M. Functional Characterization of CLPTM1L asa Lung Cancer Risk Candidate Gene in the 5p15.33 Locus. PLoS One 2012;7:e36116.
[10] Lu Y,Govindan R, Wang L, Liu PY, Goodgame B, Wen W, Sezhiyan A, Pfeifer J, Li YF,Hua X, Wang Y, Yang P, You M.MicroRNA profiling and prediction of recurrence/relapse-free survival in stageI lung cancer. Carcinogenesis. 2012 May;33(5):1046-54.