生平經歷
1996年畢業於南開大學化學系,1999年獲中科院上海藥物研究所有機化學碩士學位,2003年獲中科院上海植物生理生態研究所植物分子遺傳學博士學位。2003年11月至2006年12月,在美國University of Michigan (Ann Arbor) 進行博士後研究工作(植物揮發性物質代謝)。2006年底-2009年5月,在美國 Samuel Roberts Noble Foundation 繼續從事植物次生代謝研究(以植物腺體腺毛為研究材料)。2009年六月,入選中國科學院“百人計畫”,中科院遺傳發育所研究員。
科研項目
1、擬南芥中NAD補償途徑(salvage pathway)研究。目前該研究集中於在分子水平上對NAD補償途徑中尼古丁酸(nicotinic acid)和尼古丁醯胺(nicotinamide)的代謝合成及其體內生理功能研究。
2、植物次生代謝反應器-腺毛(glandular trichome)的基因組學,代謝組學分析及其次生代謝物合成途徑研究。目前該研究集中於啤酒花(Humulus lupulus)腺體腺毛中苦味酸代謝途徑和調控。
3、植物代謝組學技術平台的建立。以GC-MS和LC-MS/MS為分析平台,以植物和相應突變群體為分析材料,通過高通量數據分析,尋找和解析植物未知代謝途徑。
論文著作
1.Wang, G., and Dixon RA. (2009) Heterodimeric geranyl(geranyl)diphosphate synthase from hop (Humulus lupulus) and the evolution of monoterpene biosynthesis. Proc Natl Acad Sci U S A.
2.Wang G., Tian L, Aziz N, Broun P, Dai X, He J, King A, Zhao PX, and Dixon RA. (2008) Terpene biosynthesis in glandular trichomes of hop. Plant Physiol
3.Wang, G., and Pichersky, E. (2007) Nicotinamidase participates in the salvage pathway of NAD biosynthesis in Arabidopsis. Plant J
4.Wang, G., and Chen, X.. (2007) Detoxification of soil phenolic pollutants by plant secretory enzyme. In Methods in Biotechnology Vol. 23: Phytoremediation: Methods and Reviews, (Neil, W. ed.), page
5.Iijima, Y., Wang, G., Fridman, E., and Pichersky, E. (2006) Analysis of the enzymatic formation of citral in the glands of sweet basil. Arch Biochem Biophys
6.Yang Y., Varbanova M., Ross J., Wang, G., Cortes D., Fridman E., Shulaev V., Noel J.P., Pichersky E. (2005) Methylation and demethylation of plant signal molecules. In Recent Advances in Phytochemistry
7.Wang, G., Li, Q., Luo, B., and Chen, X. (2004) Ex planta phytoremediation of trichlorophenol and phenolic allelochemicals via anengineered secretory laccase. Nat. Biotechnol
8.Wang, G., and Chen, X. (2003) Laccase: properties, catalytic mechanism and applicability. Chinese Bulletin of Botany,
9.Luo, P., Wang, Y, Wang, G., Essenberg, M., and Chen, X. (2001) Molecular cloning and functional identification of (+)-delta-cadinene-8-hydroxylase, a cytochrome P450 mono-oxygenase (CYP706B1) of cotton sesquiterpene biosynthesis. Plant J
10.Luo, P., Wang, G., and Chen, X.. (2001) Isolation and expression analysis of two cDNA encoding C4H homologues from Gossypium arboretum. Acta Botanica Sinica