![楊春濤[廣州醫科大學副教授]](/img/7/8b7/nBnauM3X1MzN3QjM1IzN1kTO0UTMyITNykTO0EDMwAjMwUzLyczL3MzLt92YucmbvRWdo5Cd0FmLzE2LvoDc0RHa.jpg "楊春濤[廣州醫科大學副教授]")
科研成果
主要從事含硫化合物與疾病相關的研究。目前主持國家自然科學基金和廣東省科技計畫項目基金，並參與多項國家及省級課題的研究。曾在《ACS Chem Biol》、《Plos One》、《Cell Physiol Biochem》、《Mol Cells》、《Mol Cell Biochem》、《Clin Exp Pharmacol Physiol》以及多種國核心心期刊發表論文數十篇。
Publications
[19] Yang CT, Chen L, Xu S, Day JJ, Li X, Xian M. Recent Development of Hydrogen Sulfide Releasing/Stimulating Reagents and Their Potential Applications in Cancer and Glycometabolic Disorders. Front Pharmacol, 2017, 8 664. (IF=4.4)
[18] Yang CT, Lai ZZ, Zheng ZH, Kang JM, Xian M, Wang RY, Shi K, Meng FH, Li X, Chen L, Zhang H. A novel pH-controlled hydrogen sulfide donor protects gastric mucosa from aspirin-induced injury. J Cell Mol Med, 2017, 21 (10):2441-51. (IF=4.938)
[17] Yang CT, Meng FH, Chen L, Li X, Cen LJ, Wen HY, Li CC, Zhang H. Inhibition of Methylglyoxal-Induced AGEs/RAGE Expression Contributes to Dermal Protection by N-Acetyl-L-Cysteine. Cell Physiol Biochem, 2017, 41 (2):742-54. (IF=5.01)
[16] Kang J, Li Z, Organ CL, Park CM, Yang CT, Pacheco A, Wang D, Lefer DJ, Xian M. pH-Controlled Hydrogen Sulfide Release for Myocardial Ischemia-Reperfusion Injury. J Am Chem Soc, 2016, 138 (20):6336-9. (IF=13)
[15] Zhang H, Zhuang XD, Meng FH, Chen L, Dong XB, Liu GH, Li JH, Dong Q, Xu JD, Yang CT (corresponding author). Calcitriol prevents peripheral RSC96 Schwann neural cells from high glucose & methylglyoxal-induced injury through restoration of CBS/H2S expression. Neurochem Int, 2016, 92: 49-57. (IF=3.4)
[14] Zhao Y, Yang C, Organ C, Li Z, Bhushan S, Otsuka H, Pacheco A, Kang J, Aguilar HC, Lefer DJ, Xian M. Design, Synthesis, and Cardioprotective Effects of N-Mercapto-Based Hydrogen Sulfide Donors. J Med Chem, 2015, 58 (18):7501-11 (Joint first authors). (IF=6.2)
[13]Yang CT, Zhao Y, Xian M, et al. A Novel Controllable Hydrogen Sulfide-Releasing Molecule Protects Human Skin Keratinocytes Against Methylglyoxal-Induced Injury and Dysfunction. Cell Physiol Biochem, 2014, 34 (4):1304-1317.（IF=3.55）
[12] Dong XB,Yang CT, Zheng DD, et al. Inhibition of ROS-activated ERK1/2 pathway contributes to the protection of H(2)S against chemical hypoxia-induced injury in H9c2 cells [J]. Mol Cell Biochem, 2012, 362 (1): 149-57, (Joint first authors)
[11] Wang XY,Yang CT, Zheng DD, et al. Hydrogen sulfide protects H9c2 cells against doxorubicin-induced cardiotoxicity through inhibition of endoplasmic reticulum stress [J]. Mol Cell Biochem, 2012, 363 (2): 419-26. (Joint first authors)
[10]楊春濤, 左婉紅, 趙斌, 等. 硫化氫激活H9c2 心肌細胞容積調節性氯通道. 中國動脈硬化雜誌, 2012, 20 (6):523-7.
[09]Yang C, Yang Z, Zhang M, et al. Hydrogen Sulfide Protects against Chemical Hypoxia-Induced Cytotoxicity and Inflammation in HaCaT Cells through Inhibition of ROS/NF-kappaB/COX-2 Pathway [J]. PLoS ONE, 2011, 6 (7):e21971.
[08]Yang C, Ling H, Zhang M, et al. Oxidative stress mediates chemical hypoxia-induced injury and inflammation by activating NF-κb-COX-2 pathway in HaCaT cells [J]. Mol Cells, 2011, 31 (6):531-8.
[07] Yang Z,Yang C, Xiao L, et al. Novel insights into the role of HSP90 in cytoprotection of H2S against chemical hypoxia-induced injury in H9c2 cardiac myocytes [J]. Int J Mol Med, 2011, 28 (3):397-403.
[06]楊春濤, 凌宏忠, 曾凡欽, 等. 磷酸化NF-kB亞基p65介導化學性缺氧誘導的HaCaT細胞炎症損傷. 中華皮膚科雜誌, 2011, 44 (3):195-8.
[05]楊春濤, 楊戰利, 莫利球, 等. 環氧化酶2 介導化學性缺氧誘導的人角質形成細胞的炎症損傷作用. 中國藥理學通報, 2011, 27 (1):69-73.
[04] 張美芬,楊春濤, 楊戰利, 等. N-乙醯半胱氨酸對化學性缺氧引起HaCaT細胞損傷的保護作用. 中華皮膚科雜誌, 2010, 43 (12):859-862.
[03] Chen SL,Yang CT, Yang ZL, et al Hydrogen sulphide protects H9c2 cells against chemical hypoxia-induced injury [J]. Clin Exp Pharmacol Physiol, 2010, 37 (3):316-21. (Joint first authors)
[02] 李建平,楊春濤, 楊戰利, 等. CFTR氯通道在硫化氫誘導的心肌保護及細胞增殖中的作用. 中國病理生理雜誌, 2009, 25 (6):1070-1075.
[01] Tang XQ,Yang CT, Chen J, et al. Effect of hydrogen sulphide on beta-amyloid-induced damage in PC12 cells [J]. Clin Exp Pharmacol Physiol, 2008, 35 (2):180-6.
