4.代表性著作b] 李長欣介紹
淡江大學化學系助理教授(2003~迄今)
中央研究院生化所博士後研究員(1997-1999)
清華大學化學系博士(1997)
淡江大學化學系學士(1982-1986)
研究方向
生醫核磁共振物理化學
結構生物學
研究興趣
利用核磁共振方法研究生物分子之結構,包括生物分子之溶液結構、動態行為、ligand-receptor作用的影響等。以高解析固態MAS方法,進行 ex vivo 細胞疾病之生理代謝研究。
代表性著作
Teng-Yi Huang, Hsiao-Wen Chung, Ming-Yen Chen, Lung-Hui Giiang, Shy-Chyi Chin, Chang-Shin Lee, Cheng-Yu Chen, Yi-Jui Liu. Quantification of supratentorial CSF production rate in healthy adults: A high temporal and spatial resolution 2D cine phase-contrast MRI study. Radiology 2004; 233(2):603-8Wen-Chau Wu, Chao-Ching Huang, Hsiao-Wen Chung, Michelle Liou, Chun-Jen Hsueh, Chang-Shin Lee, Ming-Long Wu, Cheng-Yu Chen. Hippocampal Alterations in Children with Temporal Lobe Epilepsy with or without a History of Febrile Convulsions: Evaluations with MR Volumetry and Proton MR Spectroscopy. AJNR Am J Neuroradiol. 2005 May;26(5):1270-5.
Yi-Fang Tu, Cheng-Yu Chen, Chao-Ching Huang, Chang-Shin Lee. Vacuolating megalencephalic leukoencephalopathy with mild clinical course validated by diffusion tensor imaging and MR spectroscopy. AJNR Am J Neuroradiol. 2004 Jun-Jul;25(6):1041-5.
Yi-Jui Liu, Cheng-Yu Chen, Hsiao-Wen Chung, Ing-Jye Huang, Chang-Shin Lee, Shy-Chyi Chin, Michelle Liou. Temporal evolution of neuronal necrosis following ischemic injury in the middle cerebral artery territory: deep watershed versus territorial infarct subtypes on MR perfusion and spectroscopic imagings. Radiology. 2003;229:366-374
Yi-Jui Liu, Hsiao-Wen Chung, Ing-Jye Huang, Fu-Nien Wang, Shy-Chyi Chin, Chang-Shin Lee, Cheng-Yu Chen. J. Neuroimaging, 2002;12:330-338.
Lee, W. T., Lee, C. S., Pan, Y. L. and Chang C. “Temporal Changes of Cerebral Metabolites and Striatal Lesions in Acute 3-Nitropropionic Acid Intoxication in the Rat”Magn. Res. Med. 2000, 44, 29-34.
Lee, C. S., Kumar, T. K. S., Cheng, J. W., Yu, C. Main-Chain Internal Dynamics of Cardiotoxin II from Taiwan Cobra as Studied by Carbon-13 NMR at Natural Abundance: Delineation of the role of functionally important residues,” Biochemistry 1998, 37,