![李付廣[中國農業科學院棉花研究所所長]](/img/8/1e5/nBnauM3X3EjN4QzMwETM4YTM1UTM1QDN5MjM5ADMwAjMwUzLxEzL0IzLt92YucmbvRWdo5Cd0FmL0E2LvoDc0RHa.jpg "李付廣[中國農業科學院棉花研究所所長]")
人物履歷
2013年任中國農業科學院棉花研究所所長；
2004年任中國農業科學院棉花研究所副所長；
2002年破格晉升研究員；
2003年在中國農業科學院研究生院生物化學與分子生物學專業獲得博士學位；
1989年至今在中國農業科學院棉花研究所工作；
何梁何利基金1989年於中國農業大學生物學院植物生理與生物化學專業獲得學士學位；
所獲榮譽
2016獲全國優秀科技工作者；
2015中華農業英才獎；
2012年獲何梁何利基金科學與技術創新獎；
2011年獲得國家傑出青年基金
2010年獲得國家技術發明獎二等獎，排名第一；
2009年獲得國家科技進步二等獎，排名第二；
2008年榮獲中國科協求實傑出青年成果轉化獎；
2007年入選新世紀百千萬人才工程國家級人選；
2006年獲國務院政府特殊津貼；
2005年獲得國家科技進步二等獎，排名第一；
2005年榮獲農業部有突出貢獻的中青年專家稱號；
1.2016獲全國優秀科技工作者；
2.2015中華農業英才獎；
3.2012年獲何梁何利基金科學與技術創新獎；
4.2011年獲得國家傑出青年基金
5.2010年獲得國家技術發明獎二等獎，排名第一；
6.2009年獲得國家科技進步二等獎，排名第二；
7.2008年榮獲中國科協求實傑出青年成果轉化獎；
8.2007年入選新世紀百千萬人才工程國家級人選；
9.2006年獲國務院政府特殊津貼；
10.2005年獲得國家科技進步二等獎，排名第一；
11.2005年榮獲農業部有突出貢獻的中青年專家稱號；
研究成果
1. 棉花高頻再生性狀的遺傳機制與新材料創製
從棉花遺傳轉化中“轉化體系不穩定、轉化周期長”等關鍵技術瓶頸入手，以解決棉花組織培養再生體系中基因型限制、畸形胚頻率高、遺傳轉化率低等問題。研究了棉花體細胞分化規律，發明了其分化性狀的純化方法，將生產品種中棉所24的體細胞分化率篩選純化到95%、轉化率提高到51.8%，使棉花成為可直接進行大規模基因功能驗證的目標農作物，為全國從事棉花基礎研究單位提供候選基因的快速功能驗證創造了條件，先後為國內24個實驗室轉化驗證候選基因156個，促進了基礎研究成果在棉花遺傳育種中的套用進程。
建立了棉花規模化遺傳轉化體系，克服了農桿菌介導法轉化效率低、周期長的問題。創製抗蟲種質材料1479份，上交國家中期庫性狀穩定材料865份，相當於我國棉花中期庫50年來收集、引進、保存材料的1/10，對豐富棉花種質材料具有十分重要的意義；利用創製出的sGK9708、sGK中394、sGK中221等一系列具有重要育種價值的、不同基因型的、獲得轉基因安全評價證書的骨幹種質材料，與育種家合作，先後培育出中棉所41等不同生態類型的轉基因抗蟲棉花新品種32個，轉基因種質材料經全國育種家進一步引用，又衍生新品種20多個；培育的各類抗蟲棉新品種累計推廣面積1億多畝，對促進國產抗蟲棉從市場占有率的5%提升到97%以上發揮了重要作用，並創造了顯著的社會經濟效益。
2. 棉花基因組學研究
參與主持了棉花基因組計畫，並在國際上率先實施，先後完成了三個世界上最重要的棉種雷蒙徳氏棉（D5基因組）、亞洲棉（A2基因組）、陸地棉（A1A1D1D1基因組）的全基因組測序，填補了棉花沒有參考基因組圖譜的空白，為闡明棉花的起源、進化、揭示四倍體棉種及其他多倍體物種形成過程奠定了堅實的基礎，同時也為我國在世界棉花基因組學研究方面占得先機。
主持項目
1. 國家自然基金-創新研究群體項目“棉花種質創新和高產分子育種”；
2. 國家傑出青年基金“棉花高頻再生性狀的遺傳與套用研究”；
3. 國家自然基金-新疆聯合基金重點項目“棉花水分高效利用關鍵基因的挖掘及抗旱材料創製
4. 國家自然基金-面上項目“來自棉花新WD-repeat蛋白與棉花抗早衰關係的研究”；
5. 863計畫“優質高產棉花分子品種創製”
6. 973計畫“棉花纖維品質功能基因組研究與分子改良”項目第五課題；
發表論文
Li FG, Fan GY, Lu CR, Xiao GH, Zou CS, Kohel RJ, Ma ZY, Shang HH, Ma XF, Wu JYet al: Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1) provides insights into genome evolution. Nat Biotechnol 2015, 33(5):524-U242.
Li FG, Fan GY, Wang KB, Sun FM, Yuan YL, Song GL, Li Q, Ma ZY, Lu CR, Zou CSet al: Genome sequence of the cultivated cotton Gossypium arboreum. Nature genetics 2014, 46(6):567-572.
Wang K, Wang Z, Li F, Ye W, Wang J, Song G, Yue Z, Cong L, Shang H, Zhu Set al: The draft genome of a diploid cotton Gossypium raimondii. Nature genetics 2012, 44(10):1098-1103.
Yang Z, Zhang C, Yang X, Liu K, Wu Z, Zhang X, Zheng W, Xun Q, Liu C, Lu Let al: PAG1, a cotton brassinosteroid catabolism gene, modulates fiber elongation. New Phytologist 2014, 203(2):437-448.
Ge XY, Zhang CJ, Wang QH, Yang ZR, Wang Y, Zhang XY, Wu ZX, Hou YX, Wu JH, Li FG: iTRAQ Protein Profile Differential Analysis between Somatic Globular and Cotyledonary Embryos Reveals Stress, Hormone, and Respiration Involved in Increasing Plant let Regeneration of Gossypium hirsutum L. Journal of Proteome Research 2015, 14(1):268-278.
You Q, Xu W, Zhang K, Zhang L, Yi X, Yao D, Wang C, Zhang X, Zhao X, Provart NJet al: ccNET: Database of co-expression networks with functional modules for diploid and polyploidGossypium. Nucleic Acids Res 2016:gkw910.
Wang Y, Liang C, Wu S, Zhang X, Tang J, Jian G, Jiao G, Li F, Chu C: Significant Improvement of Cotton Verticillium Wilt Resistance by Manipulating the Expression of Gastrodia Antifungal Proteins. Mol Plant 2016, 9(10):1436-1439.
Sun F, Liu CL, Zhang CJ, Qi WW, Zhang XY, Wu ZX, Kong DP, Wang QH, Shang HH, Qian XYet al: A conserved RNA recognition motif (RRM) domain of Brassica napus FCA improves cotton fiber quality and yield by regulating cell size. Mol Breeding 2012, 30(1):93-101.
Yang Z, Li C, Wang Y, Zhang C, Wu Z, Zhang X, Liu C, Li F: GhAGL15s, preferentially expressed during somatic embryogenesis, promote embryogenic callus formation in cotton (Gossypium hirsutum L.). Molecular genetics and genomics : MGG 2014, 289(5):873-883.
Cheng Y, Lu L, Yang Z, Wu Z, Qin W, Yu D, Ren Z, Li Y, Wang L, Li F: GhCaM7-like, a calcium sensor gene, influences cotton fiber elongation and biomass production. Plant Physiol Biochem 2016, 109:128-136.
Zheng W, Zhang X, Yang Z, Wu J, Li F, Duan L, Liu C, Lu L, Zhang C: AtWuschel Promotes Formation of the Embryogenic Callus in Gossypium hirsutum. PLoS One 2014, 9(1):e87502.
Bello B, Zhang X, Liu C, Yang Z, Wang Q, Zhao G, Li F: Cloning of Gossypium hirsutum Sucrose Non-Fermenting 1-Related Protein Kinase 2 Gene (GhSnRK2) and Its Overexpression in Transgenic Arabidopsis Escalates Drought and Low Temperature Tolerance. PLoS One 2014, 9(11):e112269.
Zhu YX, Li FG: The Gossypium raimondii Genome, a Huge Leap Forward in Cotton Genomics. Journal of Integrative Plant Biology 2013, 55(7):570-571.
Zhang XY, Yao DX, Wang QH, Xu WY, Wei Q, Wang CC, Liu CL, Zhang CJ, Yan H, Ling Yet al: mRNA-seq Analysis of the Gossypium arboreum transcriptome Reveals Tissue Selective Signaling in Response to Water Stress during Seedling Stage. PLoS One 2013, 8(1).
Xu ZZ, Zhang CJ, Zhang XY, Liu CL, Wu ZX, Yang ZR, Zhou KH, Yang XJ, Li FG: Transcriptome Profiling Reveals Auxin and Cytokinin Regulating Somatic Embryogenesis in Different Sister Lines of Cotton Cultivar CCRI24. Journal of Integrative Plant Biology 2013, 55(7):631-642.
Xu B, Gou J-Y, Li F-G, Shangguan X-X, Zhao B, Yang C-Q, Wang L-J, Yuan S, Liu C-J, Chen X-Y: A Cotton BURP Domain Protein Interacts With α-Expansin and Their Co-Expression Promotes Plant Growth and Fruit Production. Molecular Plant 2013, 6(3):945-958.
Huang GQ, Gong SY, Xu WL, Li W, Li P, Zhang CJ, Li DD, Zheng Y, Li FG, Li XB: A Fasciclin-Like Arabinogalactan Protein, GhFLA1, Is Involved in Fiber Initiation and Elongation of Cotton. Plant Physiology 2013, 161(3):1278-1290.
Guo FD, Liu CL, Xia H, Bi YP, Zhao CZ, Zhao SZ, Hou L, Li FG, Wang XJ: Induced Expression of AtLEC1 and AtLEC2 Differentially Promotes Somatic Embryogenesis in Transgenic Tobacco Plants. PLoS One 2013, 8(8).
Zhang C, Yu S, Fan S, Zhang J, Li F: Inheritance of somatic embryogenesis using leaf petioles as explants in upland cotton. Euphytica 2011, 181(1):1-9.
Yao D, Zhang X, Zhao X, Liu C, Wang C, Zhang Z, Zhang C, Wei Q, Wang Q, Yan Het al: Transcriptome analysis reveals salt-stress-regulated biological processes and key pathways in roots of cotton (Gossypium hirsutum L.). Genomics 2011, 98(1):47-55.
Wang Q, Zhang X, Li F, Hou Y, Liu X: Identification of a UDP-glucose pyrophosphorylase from cotton (Gossypium hirsutum L.) involved in cellulose biosynthesis in Arabidopsis thaliana. Plant Cell Rep 2011.
Wang Q, Li F, Zhang X, Zhang Y, Hou Y, Zhang S, Wu Z: Purification and Characterization of a CkTLP Protein from Cynanchum komarovii Seeds that Confers Antifungal Activity. PLoS One 2011, 6(2):e16930.
Xu Z, Zhang C, Ge X, Wang N, Zhou K, Yang X, Wu Z, Zhang X, Liu C, Yang Zet al: Construction of a high-density linkage map and mapping quantitative trait loci for somatic embryogenesis using leaf petioles as explants in upland cotton (Gossypium hirsutum L.). Plant Cell Rep 2015:1-11.
Meng X, Li F, Liu C, Zhang C, Wu Z, Chen Y: Isolation and Characterization of an ERF Transcription Factor Gene from Cotton (Gossypium barbadense L.). Plant Molecular Biology Reporter 2010, 28(1):176-183.
1.Li FG, Fan GY, Lu CR, Xiao GH, Zou CS, Kohel RJ, Ma ZY, Shang HH, Ma XF, Wu JYet al: Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1) provides insights into genome evolution. Nat Biotechnol 2015, 33(5):524-U242.
2.Li FG, Fan GY, Wang KB, Sun FM, Yuan YL, Song GL, Li Q, Ma ZY, Lu CR, Zou CSet al: Genome sequence of the cultivated cotton Gossypium arboreum. Nature genetics 2014, 46(6):567-572.
3.Wang K, Wang Z, Li F, Ye W, Wang J, Song G, Yue Z, Cong L, Shang H, Zhu Set al: The draft genome of a diploid cotton Gossypium raimondii. Nature genetics 2012, 44(10):1098-1103.
4.Yang Z, Zhang C, Yang X, Liu K, Wu Z, Zhang X, Zheng W, Xun Q, Liu C, Lu Let al: PAG1, a cotton brassinosteroid catabolism gene, modulates fiber elongation. New Phytologist 2014, 203(2):437-448.
5.iTRAQ Protein Profile Differential Analysis between Somatic Globular and Cotyledonary Embryos Reveals Stress, Hormone, and Respiration Involved in Increasing Plant let Regeneration of Gossypium hirsutum L
6.You Q, Xu W, Zhang K, Zhang L, Yi X, Yao D, Wang C, Zhang X, Zhao X, Provart NJet al: ccNET: Database of co-expression networks with functional modules for diploid and polyploidGossypium. Nucleic Acids Res 2016:gkw910.
7.Significant Improvement of Cotton Verticillium Wilt Resistance by Manipulating the Expression of Gastrodia Antifungal Proteins
8.Sun F, Liu CL, Zhang CJ, Qi WW, Zhang XY, Wu ZX, Kong DP, Wang QH, Shang HH, Qian XYet al: A conserved RNA recognition motif (RRM) domain of Brassica napus FCA improves cotton fiber quality and yield by regulating cell size. Mol Breeding 2012, 30(1):93-101.
9.GhAGL15s, preferentially expressed during somatic embryogenesis, promote embryogenic callus formation in cotton (Gossypium hirsutum L.)
10.GhCaM7-like, a calcium sensor gene, influences cotton fiber elongation and biomass production
11.AtWuschel Promotes Formation of the Embryogenic Callus in Gossypium hirsutum
12.Cloning of Gossypium hirsutum Sucrose Non-Fermenting 1-Related Protein Kinase 2 Gene (GhSnRK2) and Its Overexpression in Transgenic Arabidopsis Escalates Drought and Low Temperature Tolerance
13.The Gossypium raimondii Genome, a Huge Leap Forward in Cotton Genomics
14.Zhang XY, Yao DX, Wang QH, Xu WY, Wei Q, Wang CC, Liu CL, Zhang CJ, Yan H, Ling Yet al: mRNA-seq Analysis of the Gossypium arboreum transcriptome Reveals Tissue Selective Signaling in Response to Water Stress during Seedling Stage. PLoS One 2013, 8(1).
15.Transcriptome Profiling Reveals Auxin and Cytokinin Regulating Somatic Embryogenesis in Different Sister Lines of Cotton Cultivar CCRI24
16.A Cotton BURP Domain Protein Interacts With α-Expansin and Their Co-Expression Promotes Plant Growth and Fruit Production
17.A Fasciclin-Like Arabinogalactan Protein, GhFLA1, Is Involved in Fiber Initiation and Elongation of Cotton
18.Induced Expression of AtLEC1 and AtLEC2 Differentially Promotes Somatic Embryogenesis in Transgenic Tobacco Plants
19.Inheritance of somatic embryogenesis using leaf petioles as explants in upland cotton
20.Yao D, Zhang X, Zhao X, Liu C, Wang C, Zhang Z, Zhang C, Wei Q, Wang Q, Yan Het al: Transcriptome analysis reveals salt-stress-regulated biological processes and key pathways in roots of cotton (Gossypium hirsutum L.). Genomics 2011, 98(1):47-55.
21.Identification of a UDP-glucose pyrophosphorylase from cotton (Gossypium hirsutum L.) involved in cellulose biosynthesis in Arabidopsis thaliana
22.Purification and Characterization of a CkTLP Protein from Cynanchum komarovii Seeds that Confers Antifungal Activity
23.Xu Z, Zhang C, Ge X, Wang N, Zhou K, Yang X, Wu Z, Zhang X, Liu C, Yang Zet al: Construction of a high-density linkage map and mapping quantitative trait loci for somatic embryogenesis using leaf petioles as explants in upland cotton (Gossypium hirsutum L.). Plant Cell Rep 2015:1-11.
24.Isolation and Characterization of an ERF Transcription Factor Gene from Cotton (Gossypium barbadense L.)
主編專著
《棉花分子育種學》，2013年，中國農業大學出版社；
《特種棉花及其產業化》2006年， 中國農業科學技術出版社
《轉基因抗蟲棉豐產關鍵技術》2006年，中國三峽出版社 。
1.《棉花分子育種學》，2013年，中國農業大學出版社；
2.《特種棉花及其產業化》2006年， 中國農業科學技術出版社
3.《轉基因抗蟲棉豐產關鍵技術》2006年，中國三峽出版社 。
