人物經歷
教育背景
2008年2月畢業於天津大學化工學院,獲工學博士學位。
工作經歷
2011.1-至今首都師範大學生命科學學院副教授
2010.4-2010.10 加拿大薩斯喀徹溫大學醫學院博士後
2008.4-2010.4 基因港(香港)科技有限公司及香港中文大學從事纖維素乙醇研究,Senior Scientist
2003.9-2008.2 參與代謝工程釀酒酵母工業菌株提高乙醇產量的研究(863計畫);主要構建的最佳化工程菌株“FTG2” 獲得了美國EdenIQ公司總額為95萬美元資金,用於技術許可費和合作開發資助。
研究方向
釀酒酵母戊糖和己糖代謝工程;合成生物學生產生物乙醇,丁醇和柴油等重要生物基化學品;纖維素和半纖維素降解的分子機制。
主要貢獻
發表文章
[1] Cao, L., Zhang, A., Kong, Q., Xu, X., Josine, T.L., and Chen, X. (2007). Overexpression of GLT1 in fps1DeltagpdDelta mutant for optimum ethanol formation by Saccharomyces cerevisiae. Biomol Eng 24, 638-642.
[2] Cao, L.M., Kong, Q.X., Zhang, A.L., and Chen, X. (2010). Overexpression of SYM1 in a gpdDelta mutant of Saccharomyces cerevisiae with modified ammonium assimilation for optimization of ethanol production. J Taiwan Inst Chem E 41, 2-7.
[3] Kong, Q.X., Cao, L.M., Zhang, A.L., and Chen, X. (2007a). Overexpressing GLT1 in gpd1Delta mutant to improve the production of ethanol of Saccharomyces cerevisiae. Appl Microbiol Biotechnol 73, 1382-1386.
[4] Kong, Q.X., Gu, J.G., Cao, L.M., Zhang, A.L., Chen, X., and Zhao, X.M. (2006). Improved production of ethanol by deleting FPS1 and over-expressing GLT1 in Saccharomyces cerevisiae. Biotechnol Lett 28, 2033-2038.
[5] Kong, Q.X., Zhang, A.L., Cao, L.M., and Chen, X. (2007b). Over-expressing GLT1 in a gpd2Delta mutant of Saccharomyces cerevisiae to improve ethanol production. Appl Microbiol Biotechnol 75, 1361-1366.
[6] Xu, X.J., Cao, L.M., and Chen, X. (2008). Elementary flux mode analysis for optimized ethanol yield in anaerobic fermentation of glucose with Saccharomyces cerevisiae. Chinese J Chem Eng 16, 135-142.
[7] Zhang, A., Kong, Q., Cao, L., and Chen, X. (2007). Effect of FPS1 deletion on the fermentation properties of Saccharomyces cerevisiae. Lett Appl Microbiol 44, 212-217.