人物簡介
主要研究方向是固有免疫反應的調節與信號傳導。在國內完成的工作以第一作者發表在Nature Immunology (影響因子 26.2)、Immunity (影響因子 18.3)、Blood (影響因子 10.1)、J Biol Chem (影響因子5.5) 等學術雜誌。發表論文：1Phosphatase SHP-1 promotes TLR- and RIG-I-activated production of type I interferon by inhibiting the kinase IRAK1. 論文 Nat Immunol. 2008 1 2 SHP-2 phosphatase negatively regulates the TRIFadaptorprotein-dependent type I interferon andproinflammatory cytokineproduction. 論文 Immunity. 2006 1 3 Src homology 2 domain-containing inositol-5-phosphatase 1 (SHIP1) negatively regulates TLR4-mediated LPS response primarily through a phosphatase activity- and PI-3K-independent mechanism.
