主要成就
1983年生,畢業於美國伊利諾理工大學(Illinois Institute of Technology),現任芝加哥大學外科學院高級醫學科學家(University of Chicago),美國傑出人才綠卡獲得者,主要從事生物醫學,再生醫學,組織再造,外科移植,多肽疫苗等方面的研究。參與過中國國家自然科學基金,美國國立衛生研究院,比爾和梅琳達·蓋茨基金會等項目多項。目前,發表論文SCI論文近20篇,研究成果被同行發表論文引用達500多次,同時擔任Journal of Visualized Experiments (JoVE), Annals of Laboratory Medicine, Diabetes, Obesity and Metabolism, Clinical & Experimental Immunology, Diabetologia,Kidney International - Nature,Journal of Molecular Medicine等多個國際學術期刊的審稿人,《醫藥前沿》榮譽編輯。同時,為美國Xenobiomed生物醫學公司創始人。2013年被澳大利亞SIMEFF企業雜誌專訪報導 。2014年被美國伊利諾州彩票機構評選為伊利諾州十大美籍亞太裔行業開拓者之一 ,同時入選的還有歷史首位伊利諾州女亞裔議員譚美(Tammy Duckvworth)。
2009-今 美國芝加哥大學外科學院,高級醫學科學家
2013-今 美國Xenobiomed生物醫學公司,創始人兼總裁
出版著作
近年發表學術論文:
•Thermal stability of self-assembled peptide vaccine materials.Acta Biomaterialia(2015) doi:10.1016/j.actbio.2015.11.019(IF:6.589)
•Gradated assembly of multiple proteins into supramolecular nanomaterials.Nature Materials (2014) doi:10.1038/nmat3998(IF: 35.749)
•The use of self-adjuvanting nanofiber vaccines to elicit high-affinity B cell responses to peptide antigens without inflammation.Biomaterials, 13 August 2013.(IF:8.911)
•A self-adjuvanting supramolecular assembly vaccine carrying a folded protein antigen.Advanced Healthcare Material25 FEB 2013(IF:4.5)
•1,25-Dihydroxyvitamin D Promotes Negative Feedback Regulation of TLR Signaling via Targeting MicroRNA-155–SOCS1 in Macrophages.The Journal of ImmunologyFebruary 22, 2013(IF:5.362)
•Vitamin D Receptor Signaling in Podocytes Protects against Diabetic Nephropathy.Journal of the American Society of Nephrology: JASNNovember 2, 2012(IF:9.5)
•Inhibition of renin activity by aliskiren ameliorates diabetic nephropathy in type 1 diabetes mouse model.Journal of Diabetes Mellitus2 (3), 353-360
•Modulating adaptive immune responses to peptide self-assemblies.ACS Nano Vol.6, No. 2, 1557-1546, 2012(IF:12.033)
•1,25-Dihydroxyvitamin D3 Suppresses Inflammatory Induction of Plasminogen Activator Inhibitor-1 by Blocking the Nuclear Factor-Kappa B Activation Pathway.Archives of Biochemistry and BiophysicsVolume 507, Issue 2, 15 March 2011(IF:3.252)
•Therapeutic Effects of Vitamin D Analogs on Cardiac Hypertrophy in Spontaneously Hypertensive Rats.The American Journal of Pathology, Vol. 177, No. 2, August 2010(IF:5.205)
•Combination of Vitamin D Analog and AT1 Receptor Antagonist Synergistically Blocks the Development of Diabetic Nephropathy in Type 2 Diabetes Model.Kidney International February 24, 2010; doi:10.1038/ki.2010.22(IF:8.520)
•Effects of High Intensive Exercise on Myocardial Mitochondrial Membrane Permeability Transition Pore of Rats.China Sport Science, Vol.27, No.11, 2007
•Comparisons of Some Pattern of Hypoxic-training.Sichuan Sports Science, No.2, 2007
•Heat shock protein and myocardial ischemia/reperfusion injury.Journal of Clinical Rehabilitative Tissue Engineering Research, Vol.11, No.21, July, 2007
•Coffee and Sport.Sichuan Sports Science,No.2, 2006
•Oxidative Stress and Cardiopathies.Sichuan Medical Journal, Vol.27, No.6, 2006
•Free Radical and Ischemia/Reperfusion Injury.Practical Journal of Clinical Medicine, Vol.3, No.4, July, 2006
•The Effect of Electrical Stimulation on the Diameter Change of Amputated Sciatic Nerve Induced Type I and Type II Gastrocnemius Fibers.Chinese Journal of Rehabilitation, Dec. 2006, Vol. 21 No.6