個人經歷
學習經歷
1997年12月獲無錫輕工業學院發酵工程專業博士學位;1989年12月獲無錫輕工業學院發酵工程專業碩士學位。
研究經歷
2000年6月-2001年6月,香港科技大學博士後;2003年7月-2004年12月,美國夏威夷大學訪問科學家。
社會兼職
Journal of the Science of Food & Agriculture (JSFA)副主編,
中國發酵工業協會常務
理事,中國發酵工業協會發酵工程技術工作委員會委員,中國釀酒工業協會啤酒分會副理事長,中國食品科技學會第四屆酶製劑專業委員會委員,江蘇省發酵工業協會副理事長,江蘇省生物技術協會常務理事,華南理工大學廣東省“發酵與酶工程”重點實驗室學術委員會委員。
研究領域
發酵過程最佳化與控制,酶工程與技術,代謝工程技術
主要論著
近5年來,發表SCI收錄論文102篇,其中第一作者/責任作者SCI論文43篇;出版相關著作4部。主要代表作如下:
1. Zhu Yuhong, Li Jianghua, Liu Long, Du Guocheng, Chen Jian. Production of α-ketoisocaproate via free-whole-cell biotransformation by Rhodococcusopacus DSM 43250 with L-leucine as the substrate. Enzyme and Microbial Technology. 2011, 49: 321-325
2. Zhou Haiyan, Liao Xianyan, Liu Long, Wang Tianwen, Du Guocheng, Chen Jian. Enhanced L-phenylalanine production by recombinant Escherichia coli BR-42 (pAP-B03) resistant to bacteriophage BP-1 via a two-stage feeding approach. Journal of Industrial Microbiology and Biotechnology. 2011, 38: 1219-1227
3. Zhang Zichen, Li Jianghua, Liu Long, Sun Jun, Hua Zhaozhe, Du Guocheng, Chen Jian. Enzymatic transformation of 2-O-α-D-Glucopyranosyl-L-Ascorbic acid (AA-2G) by immobilized α-cyclodextring lucanotransferase from recombinant Escherichia coli. Journal of Molecular Catalysis B: Enzymatic. 2011, 68: 223–229
4. Liu Song, Zhang Dongxu, Wang Miao, Cui Wenjing, Chen Kangkang, Liu Yi, Du Guocheng, Chen Jian, Zhou Zhemin. The pro-region of Streptomyces hygroscopicus transglutaminase affects its secretion by Escherichia coli. FEMS Microbiology Letters. 2011. 324: 98-105
5. Lin Jun, Liao Xianyan, Du Guocheng, Chen Jian. Use of Escherichia coli add/ade mutant and Saccharomyces cerevisiae WSH2 to construct a highly efficient coupled system for glutathione production. Enzyme and Microbial Technology. 2010, 48(2): 82-86
6. Wang Zhihao, Wang Yun, Zhang Dongxu, Li Jianghua, Hua Zhaozhe, Du Guocheng, Chen Jian. Enhancement of cell viability and alkaline polygalacturonate lyase production by sorbitol co-feeding with methanol in Pichia pastoris fermentation. Bioresource Technology, 2010, 101: 1318–1323
7. Liu Zhiyu, Zhang Dongxu, HuaZhaozhe, Li Jianghua, Du Guocheng and Chen Jian. Improvement of laccase production and its properties by low-energy ion implantation. Bioprocess and Biosystems Engineering. 2010, 33: 639-646
8. Lin Jun, Liao Xianyan, Du Guocheng, Chen Jian. Use of Escherichia coli add/ade mutant and Saccharomyces cerevisiae WSH2 to construct a highly efficient coupled system for glutathione production. Enzyme and Microbial Technology. 2010, 48(2): 82-86
9. Wang Zhihao, Wang Yun, Zhang Dongxu, Li Jianghua, Hua Zhaozhe, Du Guocheng, Chen Jian. Enhancement of cell viability and alkaline polygalacturonate lyase production by sorbitol co-feeding with methanol in Pichia pastoris fermentation. Bioresource Technology, 2010, 101: 1318–1323
10. Liu Zhiyu, Zhang Dongxu, HuaZhaozhe, Li Jianghua, Du Guocheng and Chen Jian. Improvement of laccase production and its properties by low-energy ion implantation. Bioprocess and Biosystems Engineering. 2010, 33: 639-646
11. Liu Long, Wang Miao, Sun Jun, Du Guocheng, Chen Jian. Application of a novel cavern volume controlled culture model to microbial hyaluronic acid production by batch culture of Streptococcus zooepidemicus. Biochemical Engineering Journal. 2010, 48: 141-147
科研項目
1.重要食品酶微生物發酵生產與高效製備關鍵技術(2011AA100905), 2011-2015年,十二五863課題;
2.解脂亞洛酵母代謝網路異位重構強化alpha-酮戊二酸積累(31171638),2012-2015年,國家自然科學基金項目;
3. 生態紡織關鍵科學問題與技術(No.IRT1135),2012-2014年,2011年度教育部“長江學者和創新團隊發展計畫”創新團隊。
]]科研成果及獎勵b]b]
近5年來完成或承擔了包括國家863項目、國家自然科學基金、“長江學者和創新團隊發展計畫”創新團隊項目等在內的國家、省部級項目11項。發表SCI收錄論文102篇,其中第一作者/責任作者SCI論文43篇;出版相關著作4部;獲授權發明專利45項,申請發明專利52項;獲得6項國家科技進步獎二等獎和省部級獎勵。獲江蘇省教學成果特等獎2項、國家教學成果二等獎1項。擔任國家精品課程“生化工程”的負責人。09年入選新世紀百千萬人才工程國家級人選、獲全國優秀教師稱號。擔任Journal of the Science of Food and Agriculture副主編。