![周樹堂[博士生導師]](/img/0/384/nBnauM3XwcDO1YDMwUzM1kTO0UTMyITNykTO0EDMwAjMwUzL1MzL2AzLt92YucmbvRWdo5Cd0FmLzE2LvoDc0RHa.jpg "周樹堂[博士生導師]")
人物簡介
1981-09-01—1985-06-30河南農業大學本科
1998-06-15—2002-12-30 加拿大Queen's University博士
![周樹堂[博士生導師]](/img/a/a01/wZwpmL3gDOyATN2IDM1kTO0UTMyITNykTO0EDMwAjMwUzLyAzLwMzLt92YucmbvRWdo5Cd0FmLwE2LvoDc0RHa.jpg)
周樹堂[博士生導師]2002年畢業於加拿大Queen’s University，獲生物化學和分子生物學博士學位。2003-2004年在Queen’s University蛋白質功能中心和生物化學系從事博士後研究，2005年後在美國Duke University Medical Center任助理研究員、助理教授。2009年入選中國科學院“百人計畫”，2010年起擔任中國科學院動物研究所研究員、博士生導師、昆蟲發育與生殖基因調控研究組組長，2011年獲“百人計畫”擇優支持。
主要成就
長期從事發育生物學，轉錄調控機制，細胞因子與信號通路，功能基因進化及環境脅迫適應等方面的研究。曾獲美國PRS NIH/NICHD Young Investigator Award，擔任Journal of Allergy and Therapy編委。近年的研究成果發表於 PNAS, Insect Biochemistry and Molecular Biology, Journal of Cell Science, American Journal of Physiology等SCI期刊上。授權國際專利1項。
研究方向
綜合運用分子生物學、生物化學、細胞生物學等手段，研究昆蟲生殖發育與變態的基因調控機制，昆蟲與寄主植物的相互作用和昆蟲適應環境脅迫的分子機理。包括昆蟲激素（保幼激素、蛻皮激素、肽激素等）或環境與寄主因子誘導下的基因轉錄與調控、蛋白表達與修飾、信號傳導等。
出版著作
1、S. Zhou*, E.Potts, F. Cuttitta, W.M. Foster, and M.E. Sunday*. Gastrin-releasing peptide blockade: broad-spectrum anti-inflammatory therapy for asthma.* Co-corresponding authors. Submitted.
2、S. Zhou, S. Degan, E.N. Potts, W.M. Foster and M.E. Sunday. 2009. NPAS3 is a trachealess homolog critical for lung development and homeostasis. Proceeding of the National Academy of Science. 106, 11699–11704.
3、B.M. Levesque*, S. Zhou*, L. Shan, Y. Kong and M.E. Sunday. 2007. NPAS1 regulates branching morphogenesis in embryonic lung. American Journal of Respiratory Cell and Molecular Biology. 36, 427-434. * contributed equally as co-first authors
4、S. Zhou, M. Tejada, G.R. Wyatt, V.K. Walker. 2006. A DNA-binding protein, tfp1, involved in juvenile hormone-regulated gene expression in Locusta migratoria. Insect Biochemistry and Molecular Biology. 36: 724-734.
5、S. Zhou, B.A. Webb, R. Eves, and A.S. Mak. 2006. Effects of Tyr-phosphorylation of cortactin on podosome-formation in A7r5 vascular smooth muscle cells. AJP-Cell Physiology.290, C463-471.
6、B.A. Webb, S. Zhou, R. Eves, and A.S. Mak. 2006. Phosphorylation of cortactin by p21-activated kinase. Archives of Biochemistry Biophysics. 456, 183-193.
7、R. Eves, B.A. Webb, S. Zhou, and A.S. Mak. 2006. Caldesmon is an integral component of podosomes in smooth muscle cells. Journal of Cell Science. 119, 1691-1702.
8、B.A. Webb, R. Eves, S. Crawley, S. Zhou, G.P., Côté and A.S. Mak. 2005. p21-activated kinase induces podosome formation in A7r5 vascular smooth muscle cells in a PIX-dependent manner. AJP-Cell Physiology. 289: C898-907.
9、D.C. Hayward, T.S. Dhadialla, S. Zhou, M.J. Kuiper, E.E. Ball, G.R. Wyatt, V.K. Walker. 2003. Ligand specificity and developmental expression of RXR and ecdysone receptor in the migratory locust. Journal of Insect Physiology. 49, 1135-1144.
10、S. Zhou, J. Zhang, M. Hirai, Y. Chinzei, H. Kayser, G.R. Wyatt, V.K. Walker. 2002. A DNA-binding protein involved in gene regulation by juvenile hormone. Molecular and Cellular Endocrinology. 190, 177-185.
11、S. Zhou, J. Zhang, M.D. Fam, G.R. Wyatt, V.K. Walker. 2002. Sequences of elongation factors-1a and -1g and stimulation by juvenile hormone in Locusta migratoria. Insect Biochemistry and Molecular Biology. 32, 1567-1576.
