個人簡介
教育背景:
1976.09至1979.09: 蘭州醫學院臨床醫學專業讀大學。
1982.01至1984.12:在山西醫學院藥理學專業讀碩士研究生。
1988.03至1989.03:公派出國在日本國岐阜大學醫學部藥理學教研室進修藥理學一年
工作經歷:
1985.04至2004.11: 在蘭州醫學院藥理學專業任教。
2004.11至2007.12:在蘭州大學藥學院藥理學專業任教。
2007.12至2009.03:在蘭州大學基礎醫學院藥理學專業任教。
2006.10至2009.03任甘肅省新藥臨床前研究重點實驗室副主任。
Resume:
Education:
Sept. 1996至June 1999 Students. in Clinical Medicine Department of Lanzhou Medical College of China。
Jan. 2002至Dec 2004 Master Degree in Pharmacology, the Department of Pharmacology of Shanxi Medical College, China。
Mar. 1988至Mar 1989 Visiting Scholar in Department of Pharmacology of Gifu University,Japan。
Working Experiences
Jul. 1997至-Now Professor, Institute of Pharmacology,School of Basic Medicine Science, Lanzhou University, China 。
Apr. 1985至Jun. 1997 A teaching assistant, then Lecturer in Department of Pharmacology,Lanzhou Medical College,.China。
科研方向
抗腫瘤藥理學。
新藥藥理學。
抗炎與免疫藥理學。
Research Interests:
Antitumor Pharmacology。
Preclinical Pharmacology of New Drugs。
Anti-inflammatory Pharmacology。
榮譽稱號及獎勵
1992年獲甘肅省青年教師成材獎。
《葡萄籽原花青素經腸給藥系統的臨床前研究》,2006年獲甘肅省科技進步2等獎,1/5。
《葡萄籽中原花青素對阿黴素增效減毒作用及機理研究》獲2006年獲甘肅省自然科學獎,(3/5)。
《組織修復及炎症過程中不同蛋白類藥物的藥理、毒理作用及其機理的實驗研究》, 2008年獲甘肅省科技進步2等獎,5/5。
1998年12月入選“333科技人才工程、甘肅省跨世紀學術技術帶頭人。2006年獲國務院政府特殊津貼。
honors and awards:
1992 obtained the honor of TheYoung Teachers Chengcai Award in Gansu Province 。
1998 obtained the honor of Academic technology leaders of Gansu Province。
2006 obtaine the second prize of Gansu Provincial Science and Technology Progress Award (First author) for Sdudy on Enteral delivery systems of Proanthocyanidin from Grape Seeds。
2006 obtained the second prize of Gansu Provincial Natural Science (Third author) for the Mechanisms of Proanthocyanidin from Grape Seeds in both Potentiating Anti-tumor Activity and Reducing Toxicity of Doxorubicin。
2006 obtained the honor of special allowance of Government of the State Council。
發表論文
LI Xiao-li, Cai Yong-qing Qin Hong WU Yong-jie (corresponding Author),The therapeutic effect and mechanism of proanthocyanidins from grape seeds in rats with TNBS-induced ulcerative colitis. Can J Physiol Pharmacol.2008;86:841-849。
崔明霞,高?,閔光寧,王莉,路莉,張寶來,吳勇傑*(通訊作者),.造模持續時間對大鼠高營養性肥胖模型製備的影響 中國藥理學通報. 2008;24(3):412-6。
李志成,覃紅,吳勇傑*(通訊作者),.大鼠肌注傷寒Vi多糖蛋白結合疫苗的長期毒性. 中國新藥雜誌. 2008;17(7):565。
孫炯,吳勇傑*(通訊作者),李文廣,高明堂.套用?窩淋巴結實驗評價干擾素的免疫毒性 中國藥理學通報 2005; 21(8):974-77。
鞠洋,路莉,吳勇傑*(通訊作者),高明堂,李文廣,閔光寧.ELISA法研究新型重組人腫瘤壞死因子在小鼠體內的藥代動力學. 中國藥理學通報 2005; 21(7):847-51。
Xiaoyu ZHANG, Decheng BAI, Yongjie WU, Wenguang LI and Naifa LIU. Proanthocyanidin from grape seeds enhances anti-tumor effect of doxorubicin both in vitro and in vivo. Pharmazie. 2005; 60(7): 533?538。
10.路莉,吳勇傑*(通訊作者),,高明堂,李文廣. 重組人鹼性成纖維細胞生長因子膠囊對大鼠慢性胃潰瘍癒合質量的影響. 中國藥理學通報 2004;20:75-8。
Chang Lin, Zhang Zhao, Wu Yong-Jie (corresponding Author), Zhu Ren-Zhi.Effects of recombinant human basic fibroblast growth factor on restenosis after arterial endothelial injury in rats. Acta Pharmacol Sin 2001; 22(10): 876-80。
ZHANG Yi, WANG Jun-zhi, WU Yong-jie and LI Wen-guang. Anti-inflammatory effect of recombinant human superoxide dismutase in rats and mice and its mechanism. Acta Pharmacologica Sinica. 2002; 23(5):439-444。
WANG Jun-zhi, WU Yong-jie, RAO Chun-ming, GAO Ming-tang and LI Wen-guang. Effect of recombinant human basic fibroblast growth factor on stomach ulcers in rats and mice. Acta Pharmacologica Sinica. 1999; 20(8):763-768。
WU Yong-jie, LI Wen-guang, ZHANG Zhen-ming and TIAN Xuan. Antioxidative activity of 4-oxy and 4-hydroxy nitroxides in tissues and erythrocytes from rats. Acta Pharmacologica Sinica. 1997; 18(6):510-514。
WANG Jun-zhi, BAI De-cheng, RAO Chun-ming, LI Wen-guang, GAO Ming-tang, WANG Xiao-qi and WU Yong-jie. Effects of 2.5s mouse nerve growth factor on regeneration of injured sciatic nerves in mice and rats. Acta Pharmacologica Sinica. 1997; 18(6):501-504。
Wu Yong-Jie,Li Xin-Fang. Effects of sodium 18 beta-glycrrhetinic acid on the production of active oxygen species and the concentration of intracellular free Ca2+ in rat neutrophils. Acta Pharmacol Sin 1991;12(2):280-4。
Wu Yong-Jie,Zhou Er-feng.Effect of methylflavonolamine on platelet aggregation in rabbits. Acta Pharmacol Sin 1988,9(1):79-83。