包永明:大連理工大學盤錦校區,食品與環境學院, 副院長,教授
主要學歷及工作經歷:
1986-7,大連輕工業學院,食品工程,工學學士學位;
1991-3,大連輕工業學院,發酵工程,工學碩士學位;
2006-6,大連理工大學,生物化工,工學博士學位。
1986年08月至1988年08月:大連輕工業學院,微生物學教研室,助教
1991年04月至1998年07月:大連輕工業學院,微生物學教研室,講師
1998年02月至1999年12月:大連輕工業學院,微生物學教研室,副教授
2000年01月至2015年11月:大連理工大學,生物科學與工程系, 教授
2015年11月至 今 :大連理工大學盤錦校區,食品與環境學院, 副院長,教授
主要學術及社會兼職:
1.遼寧省生物技術協會常務理事,專家委員會委員;
2.遼寧省生物化學學會理事;
3.遼寧省細胞生物學會理事;
4.遼寧省微生物學會理事;
5.大連市食品行業協會專家委員會委員;
6.大連市醫學會生物化學與分子生物學專業委員會理事。
研究領域:
蛋白質及酶工程、生物催化與轉化、藥物工程。
代表論文:
1. Yongming Bao*, Pengcheng Bu, Liji Jin, Wang Hongxia, Qing Yang, Lijia An. Purification, Characterization and Gene Cloning of a Novel Phospholipase A2 from the Venom of Agkistrodon blomhoffii ussurensis. International Journal of Biochemistry and Cell Biology 2005, 37(3): 558-565.
2. Xiang-Yu Wang, Yong-Ming Bao*, Li-Jia An. Purification of phospholipase A2 homologue from Agkistrodon blomhoffii ussurensis snake venom by using affinity ligand of immunoglobulin yolk. Process Biochemistry 2005, 40: 3171-3176.
3. Bao Yongming*, Bu Pengcheng, Yang Jun, Yang Wei, Jia Peilin, An Lijia. Myotoxic activity of a Gln-49 phospholipase A2 from Agkistrodon blomhoffii ussurensis snake venom. Progress in Nature Science 2006, 16(2): 178-182.
4. Siu-hong Chan#, Yongming Bao#, Ewa Ciszak, Sophie Laget, Shuang-yong Xu. Catalytic domain of restriction endonuclease BmrI as a cleavage module for engineering endonucleases with novel substrate specificities. Nucleic Acid Research 2007, 35(18):6238-48.
5. Chang Yan, Li Yingxue, Bao Yongming*, An Lijia. Neurotoxic activity of Gln49 phospholipase A (2) from Gloydius ussuriensis snake venom. Journal of Applied Toxicology 2007, 27 (5): 447-452.
6. Zhang Q, Wang J, Han Y, Xie Q, An L, Bao Y*. Identification of a novel thrombin-like phospholipase A2 from Gloydius ussuriensis snake venom. Blood Coagul Fibrinolysis 2007, 18(8):723-9.
7. Zhibo Li, Jingyun Wang, Bo Jiang, Xiuli Zhang, Lijia An, Yongming Bao*. Benzobijuglone, a novel cytotoxic compound from Juglans mandshurica, induced apoptosis in HeLa cervical cancer cells. Phytomedicine, 2007, 14(12): 846-852.
8. Penghua Zhang, Yongming Bao, Lauren Higgins, Shuang-yong Xu. Rational design of a chimeric endonuclease targeted to NotI recognition site. Protein Engineering Design & Selection 2007, 20(10): 497–504.
9. Li Zhi Bo, Bao Yong Ming, Chen Hong Bo, Wang Jing Yun, Hu Jie Han, An Li Jia. A cytotoxic compound from the leaves of Juglans mandshurica. Chinese Chemical Letters 2007, 18 (7): 846-848.
10. Bao Yongming, Higgins L, Zhang P, Chan SH, Laget S, Sweeney S, Lunnen K, Xu SY. Expression and purification of BmrI restriction endonuclease and its N-terminal cleavage domain variants. Protein Expr Purif 2008, 58(1):42-52.
11. Li Z, Wang J, Yang J, Zhang X, An L, Bao Yongming*. Apoptosis of BGC823 cell line induced by p-hydroxymethoxybenzobijuglone, a novel compound from Juglans mandshurica. Phytother Res. 2009, 23: 551-557.
12. Ling Zhao, Yongming Bao, Jingyun Wang, Boshi Liu, Lijia An. Optimization and mechanism of diacetyl accumulation by Enterobacter aerogenes mutant UV-3. World J Microbiol Biotechnol 2009, 25: 57–64.
13.Gao W, Bao Yongming, Zhang X, Wang J, An L. Characterization of Thermo-stable Endoinulinase from a New Strain Bacillus Smithii T7. Appl Biochem Biotechnol 2009, 157(3): 498-506.
14. Zhang Y, Jiang B, Li W, Zhou C, Ji F, Xie Q, Sun X, An L, Bao Yongming*. Mechanisms of Analgesic Action of Gln49-PLA2 from Gloydius ussurensis Snake Venom. Appl Biochem Biotechnol 2010, 160(3): 773-779.