Wang Kunren, physiologists, cell biologists, educators, Wang Kunren, physiologists, cell biologists, educators, . .
the Blazers in the Chinese Journal of Histochemistry of Digestive Physiology, immunohistochemistry, molecular biology and other aspects of the study, nearly 60 years in the field of education, the promotion of Chinese university and middle school biology education. They have made a great contribution to 
Introduction
Wang Kunren, March 7, 1912 born in Jiayu County as a native of Xiuning County, Anhui Province, Wang Kunren, March 7, 1912 born in Jiayu County as a native of Xiuning County, Anhui Province, . .
grandfather grandfather . are a magistrate's father and seven of the long - term unemployed, your home will decline: are a magistrate's father and seven of the long - term unemployed, your home will decline: .
Wang Kunren 9 days after birth, the mother died, my father, our home was Wang Kunren 9 days after birth, the mother died, my father, our home was . died shortly after in the Beiyang government to serve for the remainder of his uncle, Benjamin its helpless, adoption by died shortly after in the Beiyang government to serve for the remainder of his uncle, Benjamin its helpless, adoption by .
uncle after the death of my family is increasingly bleak uncle after the death of my family is increasingly bleak . Wang Kunren had to live with his aunt in paying rent in Beijing's Xuanwumen Outer Xiuning clubhouse Wang Kunren had to live with his aunt in paying rent in Beijing's Xuanwumen Outer Xiuning clubhouse .
tough environment, so that the child he fosters regardless of difficulties, for the prosperity of the tough environment, so that the child he fosters regardless of difficulties, for the prosperity of the . character in 1928,Wang Kunren after graduating from Beijing Normal University character in 1928,Wang Kunren after graduating from Beijing Normal University .
he studies hard, attending lectures, experimental operation, homework assignments, is very serious about he studies hard, attending lectures, experimental operation, homework assignments, is very serious about . to be well - read, a gathering of Chinese and foreign references, assiduously to be well - read, a gathering of Chinese and foreign references, assiduously .
in the Department of Biology, 4 years, grades always among the best in the Department of Biology, 4 years, grades always among the best . Furthermore, finding time also took up chemistry, English of course some Furthermore, finding time also took up chemistry, English of course some .
these are his work after the study has laid a solid foundation for the these are his work after the study has laid a solid foundation for the . Wang Kunren people by gentleness, and open - minded, people spend more time with his close Wang Kunren people by gentleness, and open - minded, people spend more time with his close .
1934, Wang Kunren due to excellent teaching assistant after graduation is,Responsible for Physiology and Comparative Anatomy Experiment 1934, Wang Kunren due to excellent teaching assistant after graduation is,Responsible for Physiology and Comparative Anatomy Experiment . during the summer of 1937, has been recommended to the Department of Physiology examines the refresher, the merger of the TA / RA during the summer of 1937, has been recommended to the Department of Physiology examines the refresher, the merger of the TA / RA .
commissioner he further studied physiology, biochemistry, neuro - anatomy and histology of the course, passing the exams, and in a well - known physiologist Zhang Xijun, Lin Sheng can be carried out under the guidance of work, subject to rigorous scientific training, from the rel evant documents, the design of experiments, to surgical preparation before operation, results analysis, thesis composing, etc are in earnest, meticulous commissioner he further studied physiology, biochemistry, neuro - anatomy and histology of the course, passing the exams, and in a well - known physiologist Zhang Xijun, Lin Sheng can be carried out under the guidance of work, subject to rigorous scientific training, from the rel evant documents, the design of experiments, to surgical preparation before operation, results analysis, thesis composing, etc are in earnest, meticulous . these, precise style of Wang Kunren later conducted scientific research and guidance to students, these, precise style of Wang Kunren later conducted scientific research and guidance to students,.
all had strong influence in the Pacific War, Japanese advances, grave national crisis, Wang Kunren decided to leave and has relocated to the Medical College of Beijing Normal University, Shanxi Province to all had strong influence in the Pacific War, Japanese advances, grave national crisis, Wang Kunren decided to leave and has relocated to the Medical College of Beijing Normal University, Shanxi Province to . 1939 May, Wang Kunren borrow Chuanzi, accompanied by his wife and two girls from Beiping via sea, via Hong Kong, Vietnam, Yunnan, Guizhou and Sichuan, lasted for more than four months, the travel, finally arrived in September 1939, at which point the 1939 May, Wang Kunren borrow Chuanzi, accompanied by his wife and two girls from Beiping via sea, via Hong Kong, Vietnam, Yunnan, Guizhou and Sichuan, lasted for more than four months, the travel, finally arrived in September 1939, at which point the .
Shaanxi Normal University has been renamed the Northwest Normal University, Wang Kunren Shaanxi Normal University has been renamed the Northwest Normal University, Wang Kunren . due as a result of his outstanding teaching, being promoted to associate professor in the override,Soon was promoted again to due as a result of his outstanding teaching, being promoted to associate professor in the override,Soon was promoted again to .
professor of Beijing Normal University in 1946, after moving with the school, Wang Kunren Beiping professor of Beijing Normal University in 1946, after moving with the school, Wang Kunren Beiping . in July 1947, Wang Kunren America organized by the Department of Clinical Medicine, University of Illinois School of Medicine study, only 10 months passed the thesis defense, in July 1947, Wang Kunren America organized by the Department of Clinical Medicine, University of Illinois School of Medicine study, only 10 months passed the thesis defense, .
he earned a master's degree in 1949, the peaceful liberation of Peiping. He was trying to doctor's degree and then attend the construction, but in July the same year to the North China Committee of Culture Dong Biwu, a telegram, asking him to return home at an early stage in order to participate in the construction of new China. He realizes this is the call of the motherland, then gave up the chance of their doctoral studies,declined mentor, A. C. Avenue (Ivy) professor of detainment, and in 1949 returned to Beiping
8 months after returning home, Wang Kunren, continued as a professor from Beijing Normal University, in 1952, dean of the Department of Biology, Ren 8 months after returning home, Wang Kunren, continued as a professor from Beijing Normal University, in 1952, dean of the Department of Biology, Ren . 1953 - 1958, he held a concurrent postacted as the Chinese Central Health Research Institute, a researcher with the Department of Pathology and Pathological Research Director 1953 - 1958, he held a concurrent postacted as the Chinese Central Health Research Institute, a researcher with the Department of Pathology and Pathological Research Director .
People's Republic of China all the constructions is flourishing, Wang Kunren encouraged People's Republic of China all the constructions is flourishing, Wang Kunren encouraged . To the prosperity of the motherland, he, on the one hand, and do a good job in teaching and scientific research, while at the same time began the work of the administrative burden, warmth and enthusiasm, working night and day, both by students of the beloved To the prosperity of the motherland, he, on the one hand, and do a good job in teaching and scientific research, while at the same time began the work of the administrative burden, warmth and enthusiasm, working night and day, both by students of the beloved .
in March 1956,Wang Kunren proudly joined the communist party of china in March 1956,Wang Kunren proudly joined the communist party of china . 1964 election as deputies to the Third 1964 election as deputies to the Third .
during the "cultural revolution", Wang Kunren, teaching, scientific research cannot be conducted, to be allowed to leave Beijing during the "cultural revolution", Wang Kunren, teaching, scientific research cannot be conducted, to be allowed to leave Beijing . 1976 to Beijing Institute for Cancer Research, Ren and researcher of Chinese Academy of Sciences, Cell Biology, Director, Deputy Director, determination for the anticancer and contribute their efforts 1976 to Beijing Institute for Cancer Research, Ren and researcher of Chinese Academy of Sciences, Cell Biology, Director, Deputy Director, determination for the anticancer and contribute their efforts .
1980 is regulated back to the Beijing Normal University, and worked as the dean and professor of biology, "Academic Committee, deputy director, deputy director of the school council,school teacher title appraisal committee and Biology Evaluation Team to U.S. and 1980 election as Zhuang Qiaosheng 1980 election as Zhuang Qiaosheng .
1981 - 1986 he was elected vice - chairman of the Chinese Society for Cell Biology 1981 - 1986 he was elected vice - chairman of the Chinese Society for Cell Biology . 1983, 1987, twice elected as deputies to the Beijing 1983, 1987, twice elected as deputies to the Beijing .
since 1983, Wang Kunren ceases to be a series of administrative posts, according to one of the department of biology professor, doctoral supervisor of since 1983, Wang Kunren ceases to be a series of administrative posts, according to one of the department of biology professor, doctoral supervisor of ., , .
died of illness in Beijing died of illness in Beijing.
Resume
March 17, 1912 born in Jiayu County as a 1934 graduate of Beijing Normal University March 17, 1912 born in Jiayu County as a 1934 graduate of Beijing Normal University . 1934 - 1937 Ren, an assistant professor in the Department of Biology of Beijing Normal University 1934 - 1937 Ren, an assistant professor in the Department of Biology of Beijing Normal University .
1937 - 1939 in the Medical College's Department of Physiology refresher 1937 - 1939 in the Medical College's Department of Physiology refresher . 1939 - 1946 served as the Northwest Normal University and Beijing Normal University associate professor, and 1939 - 1946 served as the Northwest Normal University and Beijing Normal University associate professor, and .
1947 - 1949 in the United States at the University of Illinois School of Medicine, Department of Clinical Medicine studies, master's degree from 1947 - 1949 in the United States at the University of Illinois School of Medicine, Department of Clinical Medicine studies, master's degree from . 1949 - 1975 Deputy Director - General of the Department of Biology of Beijing Normal University professor,since 1952 and chairman of the department of 1949 - 1975 Deputy Director - General of the Department of Biology of Beijing Normal University professor,since 1952 and chairman of the department of .
1953 - 1958, he held a concurrent postacted as the Chinese Central Health Research Institute researcher and director at 1953 - 1958, he held a concurrent postacted as the Chinese Central Health Research Institute researcher and director at . 1976 - 1980 Deputy Director - General of the Beijing Institute for Cancer Research Fellow, at the Tumour Cell Biology Laboratory of the director, deputy director of the Institute 1976 - 1980 Deputy Director - General of the Beijing Institute for Cancer Research Fellow, at the Tumour Cell Biology Laboratory of the director, deputy director of the Institute .
1981 - 1983 Deputy Director - General of the Department of Biology of Beijing Normal University professor and chairman of the department of 1981 - 1983 Deputy Director - General of the Department of Biology of Beijing Normal University professor and chairman of the department of . 1983 - -by far the Department of Biology of Beijing Normal University professor Ren 1983 - -by far the Department of Biology of Beijing Normal University professor Ren .
September 1993 of the People's Republic of China on the People's Bank of China, died of illness in Beijing September 1993 of the People's Republic of China on the People's Bank of China, died of illness in Beijing .
The Main Works
1, Wang Kunren, et al. Cell Biology. Beijing: Beijing Normal University Publishing House, 1990. (2), (KJ, Wang, Wang, Y. C. - post - Reflex (VI) - the cells of the pars nervosa. Chin J of Physiol, 1938, 13: 405. 3.Wang K J, Grossman M I. A Simplified Technique for Preparation of Section - drying Method by. J Lab Clin Med, 1949, (34): 292.Wang K J, Grossman M I. Study of Prepared by - drying Method. Anat. Rec. 1949, (104): 79.K J Wang, R. Grant et al. Action of Lysozyme on. Arch Pathol, 1950, 49: 298.C C Wang, Wang K J, Grossman M I. Effect of Ligation of duct upon action of and inch rabbit with a correlated study. of Amer J Physiol, 1950, 160: 155.C C Wang, Wang K J, Grossman M I. Alkaline Phosphatse with in Present in Tissue with Juice. Proc Soc Exp Biol and Med, 1951, 78: 310.Grant R, Grossman M I, Wang K J. et al., The Action of some and Functional Gastro - intestinal on Cells of BackgroundGastric and J. of Cellular and Comparative Phys, 1951, 37: 1. 9, Wang Kunren. adenosine triphosphate enzyme (ATPase) histochemical localization, particularly with respect to the inner wall of the gastric mucosa cells. J. Physiol., 1952, 1 (3, 4): 181. 10, Wang Kunren, Fu Cong far, Huaxing Zhang. The stimulation of the vagus nerve or injection of histamine in rabbit gastric parietal cells and chief cells in the activity of ATP enzyme histochemical study. Acta Physiological Sinica, 1955, 19 (3, 4): 281. 11, Wang Kunren, Yang Fu, Fu Cong far etc. in animal development in several digestive gland (salivary gland,Gastric and pancreatic digestive enzymes) in the normal case. Acta Nutrimenta Sinica, 1956, 1 (1): 35. 12, Wang Rihong, Wang Kunren, Yang, Corfu, etc. of the pancreas (anti - fatty liver effect of cobalt chloride on guinea pig's pancreas and liver. Acta Nutrimenta Sinica, 1956, 1 (3): 189 - 13, Wang Rihong, Wang Kunren, Yang, Corfu, etc. anti - fatty liver and pancreas; (II) and ligation of the pancreatic duct injection of cobalt chloride caused liver pancreas injury of rabbits. Acta Nutrimenta Sinica, 1956, 1 (4): 267. 14, Wang Rihong, Wang Kunren,Yang Zhongfu etc. on anti - fatty liver and pancreas; (III) produced in rats of experimental fatty liver and pancreatic tissue variation. Nutrition, 1956, 1 (4): 273. 15, Wang Kunren, Chang Hua, Zhang Huaxing etc. mouse pancreatic secretory cycle within the enzyme in situ, RNA and lipase in cytochemical changes and with the three major digestive enzymes activity. Acta Physiological Sinica, 1963, 26 (2): 108. 16, Zhang Yuan, Wang Kunren. r - globulin on ccl4 - poisoned rat of the preventive effect of Journal (Natural Science Edition), 1965, 2: 73. 17,Lu Gui Zhi, Wang Kunren, Zhang Jinzhu etc. Mice of Ehrlich ascites carcinoma cells were observed under light and electron microscope (chemical), 1981, 12 (2): 474. 18, Lin Zhongxiang, end Wang Shun, Wang Kunren, etc. of cultured normal cells and tumor cells, microtubule - Study of the microtubules in normal cells by immunofluorescence to observe , 1982, 15 (4): 439. 19, Wang Kun - ren (benevolence) Wang Kun, Zhao Ya - li, Dai Wang - shu,et al. Effects of Traditional Chinese, Toad and Adenosine 3, 5 on cAMP of Ehrlich Tumor Cells in Mice. Chinese Medical Journal, 1982, 95 (7): 527 - 532), and that of Wang Dai Shu, Zhao Lian Meng, Wang Kunren, etc.,5 different cAMP EHRLICH ASCITES CELLS AND cAMP - PDE ACTIVITY AND TUMOR CELLS cells film on its surface in certain morphological changes in the relationship. Acta Anatomica Sinica, 1983, 14 (1): 87. 21, Lin Zhongxiang, end Wang Shun, Wang Kunren, etc. of cultured normal cells and tumor cells MICROTUBULES; (II) within the microtubules of tumor cells by immunofluorescence to observe the termi nalis. Acta Biol, 1984, 17 (4): 377 - 389. 22, Zhao Yali, Monson's mother,Wang Kunren etc. S180V cells in cAMP and cGMP in the cytoskeleton and cell behavior and relationship. I. STUDIES ON CYCLIC NUCLEOTIDE CONTENT IN THE CELL CYCLE with the morphology of endothelial cells. Cell, 1984, 17 (2): 199 - 209. 23, Fang Chun, Fan Baorong, Wang Kunren, etc. of tumor mice Bw5147 cells and mouse reticulocytes fusion before and after 3, 5 - cyclic AMP phosphodiesterase enzyme cytochemical observation and termi nalis. Acta Biol, 1984, 17 (4): 415 - 421. 24, Lin Zhong Xiang, Wang Shun end,Wang Kunren etc. in human esophageal cancer cells and normal esophageal epithelial cells within the microtubule of the immunofluorescence study. Science in China, Series B, 1985, 7: 636. 25, the end Wang Shun, Gu Dong Yun, Wang Kunren etc. microtubule filament system changes on human gastric cancer cells cultured MG803 mucus secretion, 1987, 18 (2): 181 - 186. 26, Zhao Yali, Monson's mother, Wang Kunren etc. calmodulin inhibitors, trifluoperazine on tumor cell proliferation and microtubule assembly of affect. Journal of Experimental Biology, 1988, 21 (4): 481 - 491.
Scientific Achievements
Wang Kunren, for scientific research for nearly 50 years, digestive physiology, and the roles of the tumor cell biology research has made significant achievements, and has published over 70 papers and writings, main achievements include the following four aspects: (1) discovery of the vagus nerve and the posterior pituitary and reflection of the relationship, Wang Kunren in PUMC studies during Zhang Xijun, Lin Kesheng, a professor, carry through the vagus nerve and posterior pituitary Reflex of Wang Kunren, for scientific research for nearly 50 years, digestive physiology, and the roles of the tumor cell biology research has made significant achievements, and has published over 70 papers and writings, main achievements include the following four aspects: (1) discovery of the vagus nerve and the posterior pituitary and reflection of the relationship, Wang Kunren in PUMC studies during Zhang Xijun, Lin Kesheng, a professor, carry through the vagus nerve and posterior pituitary Reflex of . known posterior pituitary secretes nine hormones, but have not yet found the cytology according to known posterior pituitary secretes nine hormones, but have not yet found the cytology according to .
Wang Kunren, found that the stimulation of the vagus nerve to the dog in the end, the posterior pituitary cells is changed,while the stimulation of Central Ends of Cervical Sympathetic when there was no change in that posterior pituitary secretory cell, wherein the particles, i.e. it is a secreted product from (2) were studied with immunohistochemical method, the stomach, the pancreas cells of functional localization, Wang Kunren in Harborview Medical, Ai Wei, a professor studying a drug toxicity, Ai Wei, Wang Kunren please study the drug's renal toxicity mechanism of (2) were studied with immunohistochemical method, the stomach, the pancreas cells of functional localization, Wang Kunren in Harborview Medical, Ai Wei, a professor studying a drug toxicity, Ai Wei, Wang Kunren please study the drug's renal toxicity mechanism of .
because of the study is not the animal was placed on the conventional paraffin sections, which cannot pass through (alcohol, xylene, etc.), must be frozen vacuum drying method, to 190 degrees Celsius by liquid nitrogen fixed kidney, then low - temperature vacuum dehydration of Wang Kunren had neither experience,in the absence of any information that can be used for reference in the case, through painstaking research and repeated experiments to design a simple and practical of vacuum freezing dryer, solves the problem by Wang Kunren had neither experience,in the absence of any information that can be used for reference in the case, through painstaking research and repeated experiments to design a simple and practical of vacuum freezing dryer, solves the problem by .
instruments Comparative studies indicated that, in such a way that they could obtain a precise positioning of the instruments Comparative studies indicated that, in such a way that they could obtain a precise positioning of the . cellular enzymatic activity of this instrument is made of a solution on the new technology of the development impetus of the cellular enzymatic activity of this instrument is made of a solution on the new technology of the development impetus of the .
in glands and ATP enzyme activity of relations, Wang Kun, who also had a very meaningful work in glands and ATP enzyme activity of relations, Wang Kun, who also had a very meaningful work . gastric parietal cells is a kind of acid - secreting cells by histochemical methods can be found in parietal cells are rich of ATP enzyme, gastric parietal cells is a kind of acid - secreting cells by histochemical methods can be found in parietal cells are rich of ATP enzyme,.
significantly different from the other cells when the centrifugal end stimulation of the vagus nerve or injection of histamine, the parietal cell acid secretion is increased at the same time as the cells in the ATPase positive, indicating that cell wall production and secretion of hydrochloric acid required for ATP ATP decomposition enzyme to release the energy to be conducted with significantly different from the other cells when the centrifugal end stimulation of the vagus nerve or injection of histamine, the parietal cell acid secretion is increased at the same time as the cells in the ATPase positive, indicating that cell wall production and secretion of hydrochloric acid required for ATP ATP decomposition enzyme to release the energy to be conducted with . chloromercuric benzoic acid inhibited the secretion of hydrochloric acid, then the wall cellular ATP enzyme histochemical reactions; using L - cysteine is released and this inhibition, ATP enzyme activity is also observed the change chloromercuric benzoic acid inhibited the secretion of hydrochloric acid, then the wall cellular ATP enzyme histochemical reactions; using L - cysteine is released and this inhibition, ATP enzyme activity is also observed the change .
This is the function and localization phase and a remarkable results in the secretion by the pancreas function on This is the function and localization phase and a remarkable results in the secretion by the pancreas function on .,Renhe, Wang and his colleagues also did a series of valuable work their ,Renhe, Wang and his colleagues also did a series of valuable work their .
biochemical methods determination of pancreatic secretion period 3 kinds of digestive enzyme activity, and methods, the result shows the zymogen granules and lipase, it was found that 3 species of digestive enzyme activity by histochemical method and the obtained results, the functional activity of the worker to the cellular level, Wang Kunren, etc biochemical methods determination of pancreatic secretion period 3 kinds of digestive enzyme activity, and methods, the result shows the zymogen granules and lipase, it was found that 3 species of digestive enzyme activity by histochemical method and the obtained results, the functional activity of the worker to the cellular level, Wang Kunren, etc . the pancreas in the GPF also carried out an in - depth exploration of the the pancreas in the GPF also carried out an in - depth exploration of the .
to the injection of cobalt chloride, on islet A cells had significantly destructive effect, about half of animals had fatty liver; while in rabbit by injection of a continuous cobalt chloride with Selective Injured Islet A cells,but does not result in nonalcoholic to the injection of cobalt chloride, on islet A cells had significantly destructive effect, about half of animals had fatty liver; while in rabbit by injection of a continuous cobalt chloride with Selective Injured Islet A cells,but does not result in nonalcoholic . and vice versa, with a high cholesterol food feeding rats injected with cobalt chloride or chloroform, rats appeared severe fatty liver, the pancreas does not occur on the histological changes of and vice versa, with a high cholesterol food feeding rats injected with cobalt chloride or chloroform, rats appeared severe fatty liver, the pancreas does not occur on the histological changes of .
Accordingly, they believe that "Islet A cells is unlikely to produce lipotropic factors of location", hence the negation of some foreign scholars advocate islet A cells have lipotropic factor opinion Accordingly, they believe that "Islet A cells is unlikely to produce lipotropic factors of location", hence the negation of some foreign scholars advocate islet A cells have lipotropic factor opinion . work, Wang Kunren Zeng in July 1956, held in Brussels, Belgium, the twentieth international physiology conference report, affected by the work, Wang Kunren Zeng in July 1956, held in Brussels, Belgium, the twentieth international physiology conference report, affected by the .
, and - -Wang Kunren and her colleagues on experimental hepatic lesion induced by carbon tetrachloride in the study found, as well as the gamma globulin in rats of CCl4 poisoning prevention role , and - -Wang Kunren and her colleagues on experimental hepatic lesion induced by carbon tetrachloride in the study found, as well as the gamma globulin in rats of CCl4 poisoning prevention role . (3) Effect of cAMP on cell division, differentiation, regulation of research since the 1970s, people found that 5 '- monophosphate (cAMP) of the transformed plant cells can be reversed since the report of the scientific community has already attracted extensive attention in the Gaza Strip, Wang Kunren Binford (3) Effect of cAMP on cell division, differentiation, regulation of research since the 1970s, people found that 5 '- monophosphate (cAMP) of the transformed plant cells can be reversed since the report of the scientific community has already attracted extensive attention in the Gaza Strip, Wang Kunren Binford .
He predicting by the cancer cell reverse - AMP research and wrote a review article,China to step up research work contributed to He predicting by the cancer cell reverse - AMP research and wrote a review article,China to step up research work contributed to . Wang Kunren studied effective anticancer Chinese herbal medicine (Compound white snake wine) effect and the relationship between this Wang Kunren studied effective anticancer Chinese herbal medicine (Compound white snake wine) effect and the relationship between this .
he has a 3 - 0, 5 and cAMP Compound white snake wine processing were respectively inoculated Ehrlich ascites carcinoma in mice, found Compound white snake wine took for an animal in order to increase cAMP levels, while also the proliferation of cancer cells was obviously inhibited, and this phenomenon with cAMP and aminophylline and treated mouse Ehrlich ascites cells was thought to be similar, i.e., the cAMP level elevate,indicating that curative effect of compound Chinese medicine through cAMP control of cell proliferation achieved He also evidenced the fact that cAMP levels led to the increase of cAMP by phosphodiesterase inhibition He also evidenced the fact that cAMP levels led to the increase of cAMP by phosphodiesterase inhibition .
he and the co - worker in Polyporus umbellatus inhibit mouse sarcoma 180 ascites cells proliferation, but also get the same conclusion from these studies is the Chinese medicinal herb he and the co - worker in Polyporus umbellatus inhibit mouse sarcoma 180 ascites cells proliferation, but also get the same conclusion from these studies is the Chinese medicinal herb . control mechanism of the proliferation of cancer cells, providing valuable information control mechanism of the proliferation of cancer cells, providing valuable information .
study Once attained the beijing scientific and technological work and the Nominees AwardMinistry of Science and Technology and the Nominees Award for work and study the Prize of Academy of Traditional Chinese Medicine Grifola umbellata study Once attained the beijing scientific and technological work and the Nominees AwardMinistry of Science and Technology and the Nominees Award for work and study the Prize of Academy of Traditional Chinese Medicine Grifola umbellata . 1980 he will be "about the research in West Berlin at the Second International Society for Cell Biology, made a report by international colleagues and students 1980 he will be "about the research in West Berlin at the Second International Society for Cell Biology, made a report by international colleagues and students .
In addition, under his leadership, his team S180V lineage cell synchronization method for the determination of the different phases within the cAMP levels, and a change of a division period of the lowest, non - dividing higher In addition, under his leadership, his team S180V lineage cell synchronization method for the determination of the different phases within the cAMP levels, and a change of a division period of the lowest, non - dividing higher . from SEM observation reveals the dividing cells of skeletal system was very difficult.suggest that cancer cells with the dynamics of the cytoskeleton and the changes of the system and the morphological changes of the cells had a significant positive correlation with
cAMP treatment of cancer, also found that many of the indicators (such as cell surface receptors of ConA, microvilli, ATP activity, the membrane proteins in a lateral diffusion motion, etc.), a reverse phenomenon of the (4) is the study of the cytoskeleton and cancer at the turn of the 1980s, Wang Kunren began to notice "cytoskeleton" which is a multifunctional organelles, normal tissues of the cytoskeleton system has undergone significant change this state of affairs which affect the function of a variety of cells to change,believed that the cells of the skeletal system is likely to be one of the important target of the oncogene product in (4) is the study of the cytoskeleton and cancer at the turn of the 1980s, Wang Kunren began to notice "cytoskeleton" which is a multifunctional organelles, normal tissues of the cytoskeleton system has undergone significant change this state of affairs which affect the function of a variety of cells to change,believed that the cells of the skeletal system is likely to be one of the important target of the oncogene product in .
Wang Kunren, under the leadership of the team by indirect immunofluorescence on normal cells of the microtubule system changes, and the People's Republic of China was the only three strains within a cancer cell changes of microtubules and typing; also studied Eca109 esophageal cancer and normal esophageal epithelial cells microtubule difference Wang Kunren, under the leadership of the team by indirect immunofluorescence on normal cells of the microtubule system changes, and the People's Republic of China was the only three strains within a cancer cell changes of microtubules and typing; also studied Eca109 esophageal cancer and normal esophageal epithelial cells microtubule difference ., and the results of these studies for the early diagnosis of tumor cells and cAMP, the cytoskeleton of a tumour cell reversing the relevant theoretical foundation , and the results of these studies for the early diagnosis of tumor cells and cAMP, the cytoskeleton of a tumour cell reversing the relevant theoretical foundation .
Furthermore,He also found the effects of sodium butyrate on human gastric cancer and esophageal cancer cell Eca109 cells MG8003 of growth inhibition on human gastric carcinoma cell differentiation but also influence (such as cells (projection wall or the like tends to fibroblast morphology change), and esophageal cancer line Eca109 cell line) for Furthermore,He also found the effects of sodium butyrate on human gastric cancer and esophageal cancer cell Eca109 cells MG8003 of growth inhibition on human gastric carcinoma cell differentiation but also influence (such as cells (projection wall or the like tends to fibroblast morphology change), and esophageal cancer line Eca109 cell line) for . Wang Kunren et al found that sodium butyrate could promote the mRNA expressions of MG803 cells in gastric cancer and esophageal cancer cell Eca109 of microtubules within the intermediate filaments assembly Wang Kunren et al found that sodium butyrate could promote the mRNA expressions of MG803 cells in gastric cancer and esophageal cancer cell Eca109 of microtubules within the intermediate filaments assembly .
he thinks these are associated with Alzheimer's disease and Huntington's disease treatment after a change in cell morphology closely related he thinks these are associated with Alzheimer's disease and Huntington's disease treatment after a change in cell morphology closely related . they found,Alzheimer's disease and Huntington's disease may block the cell cycle in G1 phase, 3 -, 4 -, 5 - cAMP phosphodiesterase activity is strongly inhibited, increased cAMP levels, resulting in suppression of proliferation of the cells indicating that the they found,Alzheimer's disease and Huntington's disease may block the cell cycle in G1 phase, 3 -, 4 -, 5 - cAMP phosphodiesterase activity is strongly inhibited, increased cAMP levels, resulting in suppression of proliferation of the cells indicating that the .
(NaB) on human gastric cancer cell Eca109 esophageal MG803 and has a certain role in the (NaB) on human gastric cancer cell Eca109 esophageal MG803 and has a certain role in the . in a word, since that 1980s, Wang Kunren, their collaborators, in - depth study of the cAMP in the cell division, differentiation and cAMP, and cytoskeletal cancerization, its reversal of the relationship, and has achieved gratifying achievements in a word, since that 1980s, Wang Kunren, their collaborators, in - depth study of the cAMP in the cell division, differentiation and cAMP, and cytoskeletal cancerization, its reversal of the relationship, and has achieved gratifying achievements .
education career, Wang Kunren contribution in the field of education during the last 60 years,Both teaching and educating people, as China has cultivated a higher level of biological teaching and research talent education career, Wang Kunren contribution in the field of education during the last 60 years,Both teaching and educating people, as China has cultivated a higher level of biological teaching and research talent . his students throughout China, where some people have become experts, professor, doctorial tutor, many of who have become the backbone of good education and scientific research workers ( his students throughout China, where some people have become experts, professor, doctorial tutor, many of who have become the backbone of good education and scientific research workers (.
a) students deeply respected teacher, Wang Kunren graduating in 1934, he was appointed assistant professor, due to the serious and responsible work, skilled operation experiment, experiment, win the tie within the teachers praised a) students deeply respected teacher, Wang Kunren graduating in 1934, he was appointed assistant professor, due to the serious and responsible work, skilled operation experiment, experiment, win the tie within the teachers praised . During the War of Resistance Against Japan he taught at the Northwest Normal University, has taught at the department of biology, physiology, anatomy and histology, the department of anatomy and physiology.and the physiology of the courses, but also taught the liberal arts general biology
initially no teaching assistants, regardless of classHall demonstration, lecture, or prepare to experiment on lab to correcting our homework, he was an actor to initially no teaching assistants, regardless of classHall demonstration, lecture, or prepare to experiment on lab to correcting our homework, he was an actor to . did so, he brought his family to Shaanxi in Chongqing when passing by their advances to buy sets of physiological experiment instrument to play a role, he almost gave in PUMC drove through all of that physiological experiment, under the circumstances, It wasn't easy to did so, he brought his family to Shaanxi in Chongqing when passing by their advances to buy sets of physiological experiment instrument to play a role, he almost gave in PUMC drove through all of that physiological experiment, under the circumstances, It wasn't easy to .
anatomy experiment wasn't dead, he and other teachers to the brew instead of dogs and cats; no specimen, no pick - up main bodies strung from fleshless frames after processing using the anatomy experiment wasn't dead, he and other teachers to the brew instead of dogs and cats; no specimen, no pick - up main bodies strung from fleshless frames after processing using the . In summary, in order to improve teaching quality, Wang Kunren overcome underfunding, lack of equipment and other difficulties,self - angling for a lot of specimens and teaching aid, to meet the needs of teaching now In summary, in order to improve teaching quality, Wang Kunren overcome underfunding, lack of equipment and other difficulties,self - angling for a lot of specimens and teaching aid, to meet the needs of teaching now .
northwest areas of sport, the biology of many first - class teaching, he is a multi - cultured students when they mention the northwest areas of sport, the biology of many first - class teaching, he is a multi - cultured students when they mention the . Wang Kunren was wholeheartedly committed to the teaching of the case, all benefited greatly by, blessed, and miss her Wang Kunren was wholeheartedly committed to the teaching of the case, all benefited greatly by, blessed, and miss her .
in 1949, Wang Kunren returned from the United States, the Department of Biology of Beijing Normal University to teach physiology and histology of course. The father of , carefully preparing lessons, lectures vivid language, understandable, logical, no difficulty is stated, and also at interludes, speak of the scientific development of the new achievements, and therefore the department of biology students"Mr. Wang likes to listen to the lecture"
in the 1980s, Wang Kunren has 7 ten - years old, still insists on a postgraduate lecture, supervise postgraduate to do research, teach and counsel their students, strict in the 1980s, Wang Kunren has 7 ten - years old, still insists on a postgraduate lecture, supervise postgraduate to do research, teach and counsel their students, strict . also in previous years and other teachers for a student - written a major textbook "Cell Biology" also in previous years and other teachers for a student - written a major textbook "Cell Biology" .
(2) of running the welfare and well - being of the dean, in addition to the "Cultural Revolution" for 10 years, from 1952 to 1983, Wang Kunren has been dean of Beijing Normal University (2) of running the welfare and well - being of the dean, in addition to the "Cultural Revolution" for 10 years, from 1952 to 1983, Wang Kunren has been dean of Beijing Normal University . as an educator, he attaches particular importance to the cultivation of the talent as an educator, he attaches particular importance to the cultivation of the talent .
in the school's support and his plan, the Department of Biology, Zoology and built up a lead,Agriculture as the foundation and physiology the three seminars, in accordance with the provisions of the State on the one hand and increased recruitment of graduates, and cultivated a batch of university teachers and researchers think in the school's support and his plan, the Department of Biology, Zoology and built up a lead,Agriculture as the foundation and physiology the three seminars, in accordance with the provisions of the State on the one hand and increased recruitment of graduates, and cultivated a batch of university teachers and researchers think . Wang Kunren, to run a school, a train, not only strong leadership, also needs to have a good number of teachers; not only should make a success of the course, but also properly attributable to a series of electives; not only should notice the classroom teaching, experimental and Wang Kunren, to run a school, a train, not only strong leadership, also needs to have a good number of teachers; not only should make a success of the course, but also properly attributable to a series of electives; not only should notice the classroom teaching, experimental and .
He Chang for certain courses of the teaching quality is low and anxiety, he said: "All schools for the students, classmate listen once in a lifetime, possibly speak bad influence family life." He Chang has personally hire famous professors and experts to lecture series, is also planning to open some new courses, while at the same time appoint some of the young teachers to go abroad for training future backbone of the Department of Biology, He Chang has personally hire famous professors and experts to lecture series, is also planning to open some new courses, while at the same time appoint some of the young teachers to go abroad for training future backbone of the Department of Biology, .
he thought the teachers to improve the academic level, studies assiduously the service, it must persist in scientific research in the he thought the teachers to improve the academic level, studies assiduously the service, it must persist in scientific research in the . his advocate, the department of biology teachers in scientific research is a common sight, the achievement is his advocate, the department of biology teachers in scientific research is a common sight, the achievement is .
under his guidance, through the efforts of all students and staff,Development of the Department of Biology, as has laid a solid foundation under his guidance, through the efforts of all students and staff,Development of the Department of Biology, as has laid a solid foundation . (3) caring educator and teacher - training education of biology, Wang Kunren, a former Beijing Normal University as the Member of the Board of Governors and the Academic Committee, Deputy Director, managerial method, improving the quality of teaching, training and research in the area of the rights to carry out the major problems concerned, he was busy, always on time for meetings, and actively work for the school to present ideas for (3) caring educator and teacher - training education of biology, Wang Kunren, a former Beijing Normal University as the Member of the Board of Governors and the Academic Committee, Deputy Director, managerial method, improving the quality of teaching, training and research in the area of the rights to carry out the major problems concerned, he was busy, always on time for meetings, and actively work for the school to present ideas for .
he thinks China is a key school of Beijing Normal University, should have its own characteristic he thinks China is a key school of Beijing Normal University, should have its own characteristic . it not only take the task of cultivating outstanding middle school teachers should be given to the teachers' colleges and universities to cultivate high - quality teachers,To this end they shall endeavour to create conditions to gradually expand the postgraduates from it not only take the task of cultivating outstanding middle school teachers should be given to the teachers' colleges and universities to cultivate high - quality teachers,To this end they shall endeavour to create conditions to gradually expand the postgraduates from .
Normal University believes that he should not only emphasize the pedagogical quality, but also to improve the academic level of Normal University believes that he should not only emphasize the pedagogical quality, but also to improve the academic level of . should push ahead with scientific research, to improve the academic level, teaching quality will be ensured should push ahead with scientific research, to improve the academic level, teaching quality will be ensured .
Wang Kunren as professor, scientist, and a member of the NPC, China's interest in, primary education, the author has repeatedly called for society to bioscience education and talents, and in the National and Municipal People's Congress (NPC) on China education and the development of bioscience and put forward many valuable opinions and suggestions for Wang Kunren as professor, scientist, and a member of the NPC, China's interest in, primary education, the author has repeatedly called for society to bioscience education and talents, and in the National and Municipal People's Congress (NPC) on China education and the development of bioscience and put forward many valuable opinions and suggestions for . May 1990, he founded the Integrative Biology, under the leadership of theThe appointee, a member of Professor Qiu Weifan co - lead the Advisory Group is composed of, on the strengthening of the middle school biology teaching conducted a national review of the study, during the first half of 1992 has been a special report published in newspapers and were shadowed by the leaders and the majority of biology teachers in welcome May 1990, he founded the Integrative Biology, under the leadership of theThe appointee, a member of Professor Qiu Weifan co - lead the Advisory Group is composed of, on the strengthening of the middle school biology teaching conducted a national review of the study, during the first half of 1992 has been a special report published in newspapers and were shadowed by the leaders and the majority of biology teachers in welcome .
Wang Kunren septuagenarian has, he says to man: "I don't have much of the year, I vow to do more work in our lifetimes," his dedication and hard work always Wang Kunren septuagenarian has, he says to man: "I don't have much of the year, I vow to do more work in our lifetimes," his dedication and hard work always ., , .
his promise his promise.
