個人簡介
1984年畢業於南京大學生物系,獲學士學位;1987年於南京大學生物系獲碩士學位;2004年於南京大學生命科學院獲博士學位。
2001年,作為高級訪問學者赴美國哈佛大學醫學院Beth Israel Deaconess Medical Center開展合作研究。長期從事生殖生物學、幹細胞生物學研究,主持並參與國家自然科學基金、國家“973計畫”、教育部骨幹教師基金、江蘇省自然科學基金、江蘇省衛生廳科學基金及橫向科研項目的研究,在國內外學術刊物共發表論文90餘篇。
主持“文、理、醫結合七年制臨床醫學專業人才培養模式的最佳化與創新”、“組織胚胎學多媒體課程建設”、“生殖生物學研究生核心課程建設”等教學改革項目,參編“生殖病理學”、“組織胚胎學”教材。
任江蘇省高等學校醫藥教育研究會副理事長,江蘇省解剖學會常務理事,江蘇省製冷學會冷凍醫療專業委員會主任。
代表性成果(專業成果、學術論文、學術專著等):
【1】Wu Jiang, Fuqiang Wang, Gong Yi,Li Dongmei, Jiahao Sha, Xiaoyan Huang and Han Xiaodong*. Proteomic analysis of changes induced by nonylphenol in Sprague Dawley rat Sertoli cells. Chemical Research in Toxicology. 2009,22:668-675.
【2】Li Dongmei,G Yi, Y Chun-tao, H Yu-feng and Han Xiaodong*.Effects of subchronic methyl tert-butyl ether ether exposure on male Sprague-Dawley rats. Toxicology and Industrial Health. 2009,22:668-675.
【3】Gong Yi,Wu Jiang, Yufeng Huang, Han Xiaodong *. Nonylphenol induces apoptosis
in rat testicular Sertoli cells via endoplasmic reticulum stress. Toxicology Letters. 186(2009)84-95. 2009,186:84-95.
【4】Dongmei Li, Qin Liu, Gong Yi,Yufeng Huang, Xiaodong Han*.Cytotoxicity and Oxidative Stress Study in Cultured Rat Sertoli Cells with Methyl tert-butyl ether (MTBE) Exposure. Reproductive Toxicology.2009,27:170-176.
【5】Gong Yi, XuPing Pan, Yufeng Huang, ZiShen Gao, HongXia Yu, Han Xiaodong* . NP-induced biophysical and biochemical alterations of rat testicular Sertoli cell membranes related to disturbed intracellular Ca(2+) homeostasis. Toxicology Letters. 2008,183:10-20.
【6】Li Yan, Shen Jie, Sha Jiahao, Han Xiaodong*. The toxic effects of microcystin-LR on the reproductive system of male rats in vivo and in vitro. Reproductive Toxicology. 2008,26:239-45.
【7】Dongmei Li, Chuntao Yuan, Yi Gong, Yufeng Huang , Han Xiaodong*. The effects of methyl tert-butyl ether (MTBE) on the male rat reproductive system. Food and Chemical Toxicology 2008,46:2402–2408.
【8】Yajing Wang,Chang Chen,Tao Wu,Jing Xu, Xiaodong Han*. Methyl tert-butyl ether(MTBE) induced Ca2+-dependent cytotoxicity in isolated rabbit tracheal cells. Toxicology in Vitro.2008,22:1734-1741.
【9】Chuntao Yuan, Xuping Pan, Yi Gong, Aijun Xia, Jianqing Tang,Guanghong Wu, Xiaodong Han*. Effect of Astragalus polysaccharides(APS)on the expression of immune response genes in head kidney,gill and spleen of the common carp,Cyprinus carpio L.International Immunopharmacology.2008,8:51-58。
【10】Dongmei Li,Daqiang Yin,Han Xiaodong *. methyl tert-butyl ether(MTBE)- induced cytotoxicity and oxidative stress in isolated rat spermatogenic cells. Journal of Applied Toxicology. 2007, 27:10-17.
【11】Chuntao Yuan, Dongmei Li, Wei Chen, Fangfang Sun, Guanghong Wu, Yi Gong, Jianqing Tang, Meifang Shen, Xiaodong Han* .Administration of the herbal immunoregulation mixture (HIRM) enhances some immune parameters in carp (Cyprinus carpio) . Fish Physiology and Biochemistry .2007,33:93-101.
【12】Guanghong Wu, Chuntao Yuan, Meifang Shen, Jianqing Tang, Yi Gong, Dongmei Li, Fangfang Sun, Cheng Huang, Xiaodong Han*. Immunological and biochemical parameters in carp (Cyprinus carpio) after Qompsell feed ingredients for long-term administration. Aquaculture research.2007,38:246-255.
【13】Gong Yi,Han Xiaodong*. Nonylphenol-induced oxidative stress and cytotoxicity in testicular Sertoli cell. Reproductive Toxicology. 2006,22: 623-630.
【14】Li Dongmwi,Han Xiaodong*. Evaluation of toxicity of methyl tert-butyl ether (MTBE) on mouse spermatogenic cells in vitro. Toxicology and Industrial Health. 2006, 22: 291-299.
【15】Gong Yi,Han Xiaodong*. Effect of Nonylphenol on Steroidogenesis of Rat Leydig cells. Journal of Environmental Science and Health Part B. 2006, 41:705-715.
【16】Shuzhen Yang,Han Xiaodong *. Chen Wei, Jianxiu Chen and Daqiang Yin.The toxic effects of pentachlorophenol on rat Sertoli cells in vitro. Environmental Toxicology and Pharmacology. 2005,20:182-187.
【17】Han Xiaodong*, Zhi G. Tu, Yi Gong , Su N. Shen, Xu Y. Wang, Li N. Kang, Ya Y. Hou, Jian X. Chen. The toxic effects of nonylphenol on the reproductive system of male rats. Reproductive Toxicology. 2004, 19:215-221.
【18】Han Xiaodong*,Z.Tu,X.Wang,S.Shen. NP induced apoptosis in rat testis through Fas/FasL pathway. Bulletin of Environmental Contamination and Toxicology. 2004, 73(4):620-627.
科研項目
【1】國家自然科學基金項目(20577019):環境內分泌干擾物烷基酚生殖毒性風險評價標準的探索
【2】江蘇省環境監測中心科研項目:典型飲用水源地有機毒物與潛在健康風險的相關性研究
【3】江蘇省科技廳(BS2007050):飲用水源地有機毒物監控及其健康損害預警聯動技術研究
【4】江蘇省衛生廳科技項目(H200755):蛋白組學技術在骨髓間充質幹細胞修復移植氣
管上皮中的套用
【5】國家重點基礎研究發展計畫“973”計畫(2007CB815603):微生物群落分解礦物的機理及其對生態環境的影響
學術兼職
【1】江蘇省高等學校醫藥教育研究會副理事長
【2】江蘇省解剖學會常務理事
【3】江蘇省製冷學會冷凍醫療專業委員會主任