![許金榮[西北農林科技大學教授]](/img/7/9d1/nBnauM3XwITO3YzM5UTM0YTN1UTM1QDN5MjM5ADMwAjMwUzL1EzLwUzLt92YucmbvRWdo5Cd0FmLzE2LvoDc0RHa.jpg "許金榮[西北農林科技大學教授]")
個人經歷
曾任微生物學報副主編，現任微生物學研究學報編委，分子微生物學學報諮詢編委。是美國植病學會、真菌學會、微生物學會和遺傳學會的會員，美國植病學會遺傳組委和真菌學組委的成員。
工作簡介
1984年，北京農業大學植保與微生物系畢業, 獲學士學位；
1987年，北京農業大學植保與微生物系畢業, 獲碩士學位；
1994年，美國堪薩斯州立大學植物病理系畢業，獲博士學位；
1994年1月-1997年10月，美國普度大學生物系，博士後；
1997年10月-1999年10月，美國諾華公司農業生技所真菌靶位組，課題組長；
1999年10月-2004年7月，美國普度大學植物與植物病理系，助教授；
2004年8月-2008年7月，美國普度大學植物與植物病理系，副教授；
2008年8月至今，美國普度大學植物與植物病理系，教授；
2008年8月受聘於西北農林科技大學植物保護學院，長江學者講座教授。
現為西北農林科技大學特聘教授
研究方向與領域
以植物病原真菌的生物學與分子遺傳學為主攻方向，從基因學、功能基因學、生物信息學與分子生物學方面揭示重要病原真菌的致病機理、病原物與寄主植物的互作關係以及病原真菌信號途徑，為植物真菌病害防治的新策略制定提供理論依據。
主要研究成果
至今已發表60餘篇期刊文章，7篇書本章節，其中包括一篇《Science》(第三作者)，一篇《Nature》(作者之一)，一篇《PNAS》（第一作者），一篇《Genes & Development》（第一作者），四篇《Plant Cell》（三篇通訊作者）,一篇《Annual Rev. of Phytopathology》（第一兼通訊作者）, 四篇《Mol. Microbiology》（三篇通訊作者），十篇《MPMI》（第一或通訊作者）,五篇《Eukaryotic Cell》（四篇通訊作者),和一篇《Genetics》（第一作者）。
1) Ding, S., Liu, W., Iliuk, A., Ribot, C., Vallet, J., Wang, Y., Tao, A., Lebrun, M., and Xu, J. –R. 2010. The TIG1 HDAC complex regulates infectious growth in the rice blast fungus Magnaporthe oryzae. Plant Cell. In press.
2) Ma, L., Rep, M., Borkovich, K. A., Coleman, J. J., Daboussi, M., DiPietro, A., Dufresne, M., Freitag, M., Grabherr, M., Henrissat, B., Kang, S., Park, J., Shim, W., Woloshuk, C. Xie, X., Xu, J. –R., Antoniw, J., ………….. and Kistler, H. C. 2010. Fusarium comparative genomics reveals pathogenicity related lineage-specific genome expansion. Nature. 464: 367-373.
3) Liu, W., Xie, S., Zhao, X., Chen, X., Yi, Y., Liu, S., Lu, G., Xu, J. –R, Wang, Z. 2010. A homeodomain transcription factor is essential for asexual reproduction in a filamentous ascomycete. Molecular Plant-Microbe Interactions. 23: 366–375.
4) Yang, J., Zhao, X., Sun, J., Kang, Z., Ding, S., Xu, J. –R., Peng, Y. 2010. A novel protein Com1 is required for normal conidium morphology and full virulence in Magnaporthe oryzae. Molecular Plant-Microbe Interactions. 23: 112-123.
5) Choi, Y. E. and Xu, J. -R. 2010. The cAMP signaling pathway in Fusarium verticillioides is important for conidiation, plant infection, and stress responses but not fumonisin production. Molecular Plant-Microbe Interactions. 23: 522-533.
6) Zhou, X., Heyer, C., Choi, Y., Mehrabi, R., and Xu, J. –R. CID1 is important for plant infection in Fusarium verticillioides. 2010. Fungal Genetics and Biology. 47: 143–151.
7) John F. Leslie and Jin-Rong Xu. 2010. Fusarium genetics and pathogenicity, pp. 607-621. In: Cellular and Molecular Biology of Filamentous Fungi (eds. K. A. Borkovich & D. J. Ebbole). ASM Press, Washington, D.C.
8) Ding, S., Mehrabi, R., Koten, C., Kang, Z., Wei, Y., Seong, K., Kistler, H. C., and Xu, J. –R. 2009. The transducin beta like gene FTL1 is essential for pathogenesis in Fusarium graminearum. Eukaryotic Cell. 8: 867–876.
9) Mitchell, T., Dean, R., Xu, J. -R., Zhu, H., Oh, Y. Y., and Rho, H. 2009. Protein Chips and Chromatin Immunoprecipitation – emerging technologies to study molecule interactions in Magnaporthe grisea. pp. 73-82. In Advances in Genetics, Genomics and Control of Rice Blast Disease. Springer Publishing, Netherlands.
10) Ding, S., Zhou, X., Zhao, X., and Xu, J. -R. 2009. The PMK1 MAP kinase pathway and infection-related morphogenesis in Magnaporthe grisea. pp. 13-21. In Advances in Genetics, Genomics and Control of Rice Blast Disease. Ed. G. Wang and B. Valent. Springer Publishing, Netherlands.
11) Mehrabi, R., Zhao, X., Kim, Y., and Xu, J. –R. 2009. The cAMP signaling and MAP kinase pathways in plant pathogenic fungi. In Plant Relationship (The Mycota V) Ed. H.B. Deising, Springer. Germany. pp. 157-172.
12) Seong, K.Y., Pasquali, M., Zhou, X., Song, J., Hilburn, K., McCormick, S.P., Dong, Y., Xu, J. -R., and Kistler, H.C. 2009. Global gene regulation by Fusarium transcription factors Tri6 and Tri10 reveals adaptations for toxin biosynthesis. Molecular Microbiology. 72: 354-367.
13) Barhoom, S., Kupiec, M., Zhao, X., Xu, J. -R., and Sharon, A. 2008. Functional characterization of cgCTR2, a vacuole copper transporter that is involved in germination and pathogenicity of Colletotrichum gloeosporioides. Eukaryotic Cell. 7: 1098–1108.
14) Mehrabi, R., Ding, S., and Xu, J. -R. 2008. The MADS-box transcription factor Mig1 is required for infectious growth in Magnaporthe grisea. Eukaryotic Cell. 7: 791–799.
15) Seong, K, Zhao, X., Xu, J. -R, Güldener, U., and Kistler, H. C. 2008. Conidial germination in the filamentous fungus Fusarium graminearum. Fungal Genetics and Biology. 45: 389-399 (journal cover).
16) Zhao, X., Mehrabi, R., and Xu, J. -R. 2007. MAP kinase pathways and fungal pathogenesis. Eukaryotic Cell. 10: 1701-1714. (18184)
17) Cuomo, C., Güldener, U., Xu, J. -R, Trail, F., Turgeon, B. G., ………… and Kistler, H. C. 2007. The genome sequence of Fusarium graminearum reveals localized diversity and pathogen specialization. Science. 317: 1402-1405.
18) Betts, M. F., Tucker, S. L., Galadima, N., Meng, Y., Patel, G., Li, L., Donofrio, N. M., Floyd, A., Nolin, S., Brown, D., Mandel, M. A., Mitchell, T. K., Xu, J. -R., Dean, R. A., Farman, M. L., Orbach, M. J. 2007. Development of a high throughput transformation system for insertional mutagenesis in Magnaporthe oryzae. Fungal Genetics and Biology. 44: 1035-1049.
19) Meng, Y., Patel, G., Heist, M., Betts, M., Tucker, S. L., Donofrio, N. M., Brown, D., Mitchell, T. K., Li, L., Xu, J. -R., Orbach, M. J., Thon, M., Dean, R. A., and Farman, M. L. 2007. A systematic analysis of T-DNA insertion events in Magnaporthe oryzae. Fungal Genetics and Biology. 44: 1050-1064.
20) Bluhm, B. H., Zhao, Z., Flaherty, J., Xu, J. -R., and Dunkle, L. D. 2007. RAS1 regulates growth and pathogenesis in Fusarium graminearum. Molecular Plant-Microbe Interactions. 20: 627-636. (18031)
21) Li, L., Ding, S., Orbach, M., Sharon, A., and Xu, J. -R. 2007. A novel nuclear protein MIR1 is highly up-regulated during infectious hyphal growth in the rice blast fungus. Molecular Plant-Microbe Interactions. 20: 448-458. (18185)
22) Ramamoorthy, V., Zhao, X., Snyder, A. K., Xu, J. -R., and Shah, D. M. 2007. Two Mitogen-activated protein kinase signaling cascades regulate sensitivity to antifungal plant defensins in Fusarium graminearum. Cellular Microbiology. 9: 1491–1506.
23) Zhao, X., and Xu, J. -R. 2007. A highly-conserved MAPK-docking site in Mst7 is essential for Pmk1 activation in Magnaporthe grisea. Molecular Microbiology. 63: 881–894. (18033)
24) Xu, J. -R., Zhao, X., and Dean, R. A. 2007. From genes to genomes; a new paradigm for studying fungal pathogenesis in Magnaporthe oryzae. In Advances in Genetics (Fungal Genomics) 57: 175-218. (18188)
25) Park, G., Xue, C., Zhao, X., Kim, Y., Orbach, M., and Xu, J. -R. 2006. Multiple upstream signals converge on an adaptor protein Mst50 to activate the PMK1 pathway in Magnaporthe grisea. The Plant Cell. 18: 2822–2835. (18032)
26) Soderlund, C., Pampanwar, V., Haller, K., Ebbole, D., Farman, M., Mitchel, T., Orbach, M., Wang, G., Wing, R., Xu, J. -R., and Dean, R. 2006. MGOS: a resource for studying Magnaporthe grisea and Oryza sativa interactions. Molecular Plant-Microbe Interactions. 19: 1055-1061.
27) Xu, J. -R., Peng, Y., Dickman, M. B., and Sharon, A. 2006.The dawn of fungal pathogen genomics. Annual Reviews of Phytopathology. 44: 337-366. (18034)
28) Goswami, R. S., Xu, J. -R., Trail, F., Hilburn, K., and Kistler, H. C. 2006. Genomic analysis of host-pathogen interaction between Fusarium graminearum and wheat during early stages of disease development. Microbiology. 6: 1877-1890.
29) Güldener, U., Seong, K., Boddu, J., Cho, S., Trail, F., Xu, J. -R., Adam, G., Mewes, H., Muehlbauer, G. J., and Kistler, H. C. 2006. Development of a Fusarium graminearum Affymetrix GeneChip for profiling fungal gene expression in vitro and in planta. Fungal Genetics and Biology. 43: 316-325.
30) Seong, K., Li, L., Hou, Z., Kistler, H. C., and Xu, J. -R. 2006. Cryptic promoter activity of the HMR1 coding region in the wheat scab fungus Fusarium graminearum. Fungal Genetics and Biology. 43: 34-41. (17825) Journal Cover
31) Seong, K., Hou, Z., Kistler, H. C., and Xu, J. -R. 2005. Random insertional mutagenesis identifies genes associated with virulence in the wheat scab fungus Fusarium graminearum. Phytopathology. 95 (7): 744-750. (17664) Journal Cover
32) Dean, R., Talbot, N., Ebbole, D., Farman, M., Mitchell, T., Orbach, M., Thon, M., Kulkarni, R., Xu, J. -R., Pan, H., Read, N., Lee, Y., ……..….… and Birren, B. 2005. Analysis of the genome sequence of the plant pathogenic fungus Magnaporthe grisea, the causal agent of rice blast disease. Nature. 434: 980-986.
33) Zhao, X., Kim, Y., Park, G., and Xu, J. -R. 2005. A MAP kinase cascade regulating infection-related morphogenesis in Magnaporthe grisea. The Plant Cell. 17 (4): 1317-1329. (17663)
34) Xue, C., Li, L., Seong, K, and Xu, J. -R. 2004. The Magnaporthe grisea – rice interaction: A model system for studying fungal-plant interactions. pp. 138-165. In Plant-Pathogen Interactions. Ed. N. J. Talbot, Blackwell Scientific Publishers, UK. (Invited book chapter).
35) Xu, J. -R. and Wang, G. 2004. Rice Blast. pp.1-4. In The Encyclopedia of Plant and Crop Science (ISBN: 0-8247-4268-0). Ed. R. Goodman, Marcel Dekker, Inc. 270 Madison Ave. New York, USA.
36) Park, G., and Xu, J. -R. 2004. Mechanisms of Infection-Imperfect Fungi. pp.694-696. In The Encyclopedia of Plant and Crop Science (ISBN: 0-8247-4268-0). Ed. R. Goodman, Marcel Dekker, Inc. 270 Madison Ave. New York, USA.
37) Zhao, X., Xue, C., Kim, Y., and Xu, J. -R. 2004. A Ligation-PCR approach for generating gene replacement constructs in Magnaporthe grisea. Fungal Genetics Newsletter. 51: 17-18. (17662)
38) Bruno, K., F. Tenjo, Li, L., Hamer, J., and Xu, J. -R. 2004. Expression and localization of PMK1 during different plant infection stages. Eukaryotic Cell. 3: 1525-1532. (17522)
39) Park, G., Bruno, K., Talbot, N., Staiger, C., and Xu, J. -R. 2004. Independent genetic mechanisms mediate turgor generation and penetration peg formation during plant infection in the rice blast fungus. Molecular Microbiology. 53: 1695-1707. (17311)
40) Li, L., Xue, C. Y., Bruno, K., Nishimura, M., and Xu, J. -R. 2004. Two PAK kinase genes MST20 and CHM1 have distinct functions in Magnaporthe grisea. Molecular Plant-Microbe Interactions. 17: 547-556. (17141).
41) Nishimura, M., Park, G., and Xu, J. -R. 2003. The G-beta subunit MGB1 is involved in regulating multiple steps of infection-related morphogenesis in Magnaporthe grisea. Molecular Microbiology. 50: 231-243. (17140)
42) Trail, F., Xu, J. -R., San Miguel, P., Halgren, R. G., and Kistler, H. C. 2003. Analysis of Expressed Sequence Tags from Gibberella zeae (anamorph Fusarium graminearum). Fungal Genetics and Biology 38: 187-197. (16895)
43) Hou, Z., Xue, C., Katan, T., Peng, Y., Kistler, H. C., and Xu, J. -R. 2002. A MAP kinase gene (MGV1) for hyphal growth and plant infection in Fusarium graminearum. Molecular Plant-Microbe Interactions. 15: 1119-1127. (16853)
44) Xue, C., Park, G., Choi, W., Zheng, L., Dean, R. A., and Xu, J. -R. 2002. Two novel fungal virulence genes specifically expressed in appressoria of the rice blast fungus. The Plant Cell. 14: 2107-2119. (16752)
45) Zhang, Y., Lamm, R., Pillonel, C., Lam, S., and Xu, J. -R. 2002. Osmoregulation and fungicide resistance: the Neurospora crassa OS-2 gene encodes a HOG1 MAP kinase homologue. Applied and Environmental Microbiology. 68: 532-538. (16663)
46) Xu, J. -R., and Xue, C. 2002. Time for a blast: genomics of Magnaporthe grisea. Molecular Plant Pathology. 3: 173-176. (16731)
47) Park, G., Xue, C., Zheng, L., Lam, S., and Xu, J. -R. 2002. MST12 regulates infectious growth but not appressorium formation in the rice blast fungus Magnaporthe grisea. Molecular Plant-Microbe Interactions. 15: 183-192. (16662)
48) Xu, J. -R. 2000. MAP kinases in fungal pathogens. Fungal Genetics and Biology. 31: 137-152. (16298)
49) Zheng, L., Campbell, M., Murray, J., Lam, S., and Xu, J. -R. 2000. The BMP1 gene is essential for pathogenicity in the gray mold fungus Botrytis cinerea. Molecular Plant-Microbe Interactions. 13: 724-732.
50) Dixon, K., Xu, J. -R., Smirnoff, N., and N. J. Talbot. 1999. Independent signaling pathways regulate cellular turgor during hyperosmotic stress and appressorium-mediated plant infection by Magnaporthe grisea. The Plant Cell. 11: 2045-2058.
51) Xu, J. -R., Staiger, C., and J. E. Hamer. 1998. Inactivation of the mitogen-activated protein kinase Mps1 from the rice blast fungus prevents penetration of host cells but allows activation of plant defense responses. Proceeding of the National Academy of Sciences (USA). 95: 12713-12718.
52) Hamer, J. E., Xu, J. -R., Urban, M., Adachi, K. 1998. Signal transduction and gene expression during early stages of fungal phytopathogenesis in the rice blast fungus. pp 225-244. In Molecular Genetics of Host-Specific Toxins in Plant Disease, ed. K. Kohmoto and O. C. Yoder), Kluwer Academic Publisher, Netherlands
53) Xu, J. -R., Urban, M., Sweigard, J., and J. E. Hamer. 1997. cAMP dependent protein kinase is essential for forming functional appressoria in Magnaporthe grisea. Molecular Plant-Microbe Interactions. 10: 187-194.
54) Xu, J. -R. and J. E. Hamer. 1996. MAP Kinase and cAMP signaling regulate infection structure formation and pathogenic growth in the rice blast fungus Magnaporthe grisea. Genes & Development. 10: 2696-2706.
55) Xu, J. -R. and J. F. Leslie. 1996. A RFLP map of Gibberella fujikuroi mating population A. Genetics. 143: 175-189.
56) Xu, J. -R. and J. F. Leslie. 1996. Strain genotypes of Gibberella fujikuroi mating population A (Fusarium moniliforme) mapping population. Fungal Genetics Newsletter. 43: 61-65.
57) Xu, J. -R. and J. E. Hamer. 1995. Assessment of Magnaporthe grisea mating type by spore PCR. Fungal Genetics Newsletter. 42: 80-81.
58) Xu, J. -R., Leslie, J. F., Yan, K. and Dickman, M. B. 1995. Electrophoretic karyotypes distinguish the biological species of Gibberella fujikuroi (Fusarium section Liseola). Molecular Plant-Microbe Interactions. 8: 74-84.
59) Xu, J. -R. and Leslie, J. F. 1993. A computer program for constructing classical genetic linkage maps in haploid fungi. Fungal Genetics Newsletter. 40: 80-82.
60) Yan, K., Dickman, M.B., Xu, J. -R. and Leslie, J. F. 1993. Sensitivity of field strains of Gibberella fujikuroi (Fusarium section Liseola) to benomyl and hygromycin B. Mycologia. 85: 206-213.
