研究方向
（1）納米生物材料的功能設計及其合成
（2）智慧型醫用高分子材料的設計、合成及其套用
（3）小分子靶向藥物的合成及其在腫瘤診療和轉化醫學等領域中的套用
代表性學術論文
1. Zhigang Xu, Shiying Liu, Hui Liu, Cangjie Yang, Yuejun Kang and Mingfeng Wang, Unimolecular micelles of amphiphilic cyclodextrin-core star-like block copolymers for anticancer drug delivery, Chemical Communication , 2015, DOI: 10.1039/C5CC02743H
2. Zhigang Xu, Shiying Liu, Yuejun Kang, Mingfeng Wang, Glutathione- and pH-responsive nonporous silica prodrug nanoparticles for controlled release and cancer therapy, Nanoscale 2015 , 7, 5859-5868
3. Zhigang Xu, Shiying Liu, Yuejun Kang, Mingfeng Wang, Glutathione responsive polymeric micelles formed by a biodegradable amphiphilic triblock copolymer for anticancer drug delivery and controlled release, ACS Biomaterials Science & Engineering 2015 , 1, 585-592
4. Zhigang Xu, Kelin Zhang, Cuilan Hou , Dongdong Wang, Xiaoyan Liu, Xiujuan Guan, Xiaoyu Zhang, Haixia Zhang. A novel nanoassembled doxorubicin prodrug with a high drug loading for anticancer drug delivery,Journal of Materials Chemistry B, 2014, 2, 3433 – 3437
5. Zhigang Xu, Dongdong Wang, Xiaoyan Liu, Xiaoyu Zhang, Haixia Zhang. Preparation of a Camptothecin Prodrug with Glutathione-Responsive Disulfide Linker for Anticancer Drug Delivery, Chemistry – An Asian Journal, 2014,9, 199-205
6. Zhigang Xu, Dongdong Wang, Xiaoyan Liu, Haixia Zhang, A New Strategy to Prepare Glutathione Responsive Silica Nanoparticles. RSC Advances, 2013,3, 17700-17702.
7. Zhigang Xu, Dongdong Wang, Min Guan, Xiaoyan Liu, Yanjie Yang, Dongfeng Wei, Chunyan Zhao, Haixia Zhang. Photoluminescent Silicon Nanocrystal-Based Multifunctional Carrier for pH-Regulated Drug Delivery. ACS Applied Materials & Interfaces, 2012, 4, 3424–3431.
8. Zhigang Xu, Bo Li, Wanjin Tang, Tong Chen, Haixia Zhang, Qin Wang. Glyco -polypeptide-encapsulated Mn-doped ZnS quantum dots for drug delivery: Fabrication, characterization, and in vitro assessment. Colloids and Surfaces B: Biointerfaces, 2011,88, 51– 57.
9. Zhigang Xu, Yaoyao Feng, Xiaoyan Liu, Min Guan, Chuande Zhao, Haixia Zhang*, Synthesis and characterization of FeO@SiO@poly-l-alanine, peptide brush–magnetic microspheres through NCA chemistry for drug delivery and enrichment of BSA. Colloids and Surfaces B: Biointerfaces, 2010, 81, 503–507.
10. Zhigang Xu, Yongsheng Ji,, Min Guan, Huayu Huang, Chuande Zhao, Haixia Zhang, Preparation and characterization of L-Leucine-modified amphiprotic bifunctional mesoporous SBA-15 molecular sieve as a drug carrier for ribavirin. Applied Surface Science 2010, 256, 3160–3165.
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