人物經歷
博士畢業後赴美國普渡大學生物化學系與癌症中心從事博士後研究，現通過吉林大學“優秀人才引進計畫”以學術骨幹身份加入吉林大學生命科學學院。
目前為止，已在Angew. Chem. Int. Ed., Anal. Chem., J. Proteome Res.等雜誌上發表論文20 余篇，他人引用600 余次，參與撰寫英文著作兩章，申請國家發明專利兩項，多次在國際國內學術會議上做口頭報告，並榮獲第六屆亞太人類蛋白質組學大會“Young Scientist Travel Award” Best Winner。現為美國質譜學會(ASMS)會員，J. Chromatogr. A, Anal. Chim. Acta,《高等學校化學學報》和《色譜》等雜誌審稿人，主持國家自然科學基金兩項，2012年入選教育部“新世紀優秀人才支持計畫”。
個人成就
Lianghai Hu,Li Yang,Lipchik AM,Geahlen RL, W. Andy Tao. A Quantitative Proteomics-Based Competition Binding Assay to Characterize pITAM-Protein Interactions. Anal. Chem. 2013, 85, 5071-5077.
Lianghai Hu, John Paul Fawcett, Jingkai Gu. Protein target discovery of drug and its reactive intermediate metabolite by using proteomic strategy. Acta Pharm. Sinica B 2012, 2, 126-136. (Invited Review)
Lianghai Hu, Anton Iliuk, Jacob Galan, Michael Hans, W. Andy Tao. Identification of drug targets in vitro and in living cells by soluble nanopolymer-based proteomics. Angew. Chem. Int. Ed. 2011, 50, 4133-4136. (Hot Paper)
Anton Iliuk, Lianghai Hu, W. Andy Tao. Aptamer in bioanalytical applications. Anal. Chem. 2011, 83, 4440-4452.
Lianghai Hu, Houjiang Zhou, Yinghua Li, Shutao Sun, Lihai Guo, Mingliang Ye, Xiaofeng Tian, Jianren Gu, Shengli Yang, Hanfa Zou. Profiling of endogenous serum phosphorylated peptides by titanium (Ⅳ) immobilized mesoporous silica particles enrichment and MALDI-TOF MS detection. Anal. Chem., 2009, 81, 94–104.
Lianghai Hu, Mingliang Ye, Hanfa Zou, Recent advances in mass spectrometry-based peptidome analysis. Expert Rev. Proteomics, 2009, 6(4), 433-447136. (Invited Review)
Lianghai Hu, Karl-Siegfried Boos, Mingliang Ye, Ren’an Wu, Hanfa Zou, Selective on-line serum peptide extraction and multidimensional separation by coupling a restricted access material-based capillary trap column with nanoLC-MS/MS. J. Chromatogr. A, 2009, 1216, 5377-5384.
Lianghai Hu, Xin Li, Xinning Jiang, Houjiang Zhou, Xiaogang Jiang, Liang Kong, Mingliang Ye, Hanfa Zou, Comprehensive peptidome analysis of mouse livers by size exclusion chromatography prefractionation and nanoLC-MS/MS identification. J. Proteome Res., 2007, 6, 801-808.
Lianghai Hu, Xueguo Chen, Liang Kong, Xingye Su, Mingliang Ye, Hanfa Zou, Improved performance of comprehensive two-dimensional HPLC separation of traditional Chinese medicines by using a silica monolithic colum n and normalization of peak heights. J. Chromatogr. A, 2005, 1092, 191-198.
Liang Xue, Wenhong Wang, Anton Iliuk, Lianghai Hu, Galan JA, Yu S, Hans M, Geahlen RL, Tao WA, Sensitive kinase assay linked with phosphoproteomics for identifying direct kinase substrates. Proc. Natl. Acad. Sci. 2012,109(15):5615-5620
1.Lianghai Hu,Li Yang,Lipchik AM,Geahlen RL, W. Andy Tao. A Quantitative Proteomics-Based Competition Binding Assay to Characterize pITAM-Protein Interactions. Anal. Chem. 2013, 85, 5071-5077.
2.Lianghai Hu, John Paul Fawcett, Jingkai Gu. Protein target discovery of drug and its reactive intermediate metabolite by using proteomic strategy. Acta Pharm. Sinica B 2012, 2, 126-136. (Invited Review)
3.Lianghai Hu, Anton Iliuk, Jacob Galan, Michael Hans, W. Andy Tao. Identification of drug targets in vitro and in living cells by soluble nanopolymer-based proteomics. Angew. Chem. Int. Ed. 2011, 50, 4133-4136. (Hot Paper)
4.Anton Iliuk, Lianghai Hu, W. Andy Tao. Aptamer in bioanalytical applications. Anal. Chem. 2011, 83, 4440-4452.
5.Lianghai Hu, Houjiang Zhou, Yinghua Li, Shutao Sun, Lihai Guo, Mingliang Ye, Xiaofeng Tian, Jianren Gu, Shengli Yang, Hanfa Zou. Profiling of endogenous serum phosphorylated peptides by titanium (Ⅳ) immobilized mesoporous silica particles enrichment and MALDI-TOF MS detection. Anal. Chem., 2009, 81, 94–104.
6.Lianghai Hu, Mingliang Ye, Hanfa Zou, Recent advances in mass spectrometry-based peptidome analysis. Expert Rev. Proteomics, 2009, 6(4), 433-447136. (Invited Review)
7.Lianghai Hu, Karl-Siegfried Boos, Mingliang Ye, Ren’an Wu, Hanfa Zou, Selective on-line serum peptide extraction and multidimensional separation by coupling a restricted access material-based capillary trap column with nanoLC-MS/MS. J. Chromatogr. A, 2009, 1216, 5377-5384.
8.Lianghai Hu, Xin Li, Xinning Jiang, Houjiang Zhou, Xiaogang Jiang, Liang Kong, Mingliang Ye, Hanfa Zou, Comprehensive peptidome analysis of mouse livers by size exclusion chromatography prefractionation and nanoLC-MS/MS identification. J. Proteome Res., 2007, 6, 801-808.
9.Lianghai Hu, Xueguo Chen, Liang Kong, Xingye Su, Mingliang Ye, Hanfa Zou, Improved performance of comprehensive two-dimensional HPLC separation of traditional Chinese medicines by using a silica monolithic colum n and normalization of peak heights. J. Chromatogr. A, 2005, 1092, 191-198.
10.Liang Xue, Wenhong Wang, Anton Iliuk, Lianghai Hu, Galan JA, Yu S, Hans M, Geahlen RL, Tao WA, Sensitive kinase assay linked with phosphoproteomics for identifying direct kinase substrates. Proc. Natl. Acad. Sci. 2012,109(15):5615-5620
