主要貢獻
論文發表
A． SCI期刊 (*Corresponding author)
(1) Cheng G*, Luo R, Hu C, Lin J, Bai Z, Zhang B, Wang H. TiO2-based phosphoproteomic analysis of schistosomes: characterization of phosphorylated proteins in the different stages and sex of Schistosoma japonicum. J Proteome Res. 2013 Feb 1;12(2):729-42. (2011 SCI IF=5.11).
(2) Luo R, Zhou C, Shi Y, Zhao J, Cheng G*. Molecular characterization of a cytokine-induced apoptosis inhibitor from Schistosoma japonicum. Parasitol Res. 2012 Dec;111(6):2317-24. (2011 SCI IF=2.149).
(3) Cheng G* and Jin YX. microRNAs: Potentially Important Regulators for Schistosome Development and Therapeutic Targets against Schistosomiasis. Parasitology. 2012 Apr;139(5):669-79. (2011 SCI IF=2.96).
(4) Luo R, Zhou C, Lin J, Yang D, Shi Y, Cheng G*. Identification of in vivo protein phosphorylation sites in human pathogen Schistosoma japonicum by a phosphoproteomic approach. J Proteomics. 2012, 75(3):868-77. (2010 SCI IF=5.047)
(5) Chen J, Yang Y, Guo S, Peng J, Liu Z, Li J, Lin J*, Cheng G*. Molecular cloning and expression profiles of Argonaute proteins in Schistosoma japonicum. Parasitol Res. 2010;107(4):889-99. (2010 SCI IF=1.812)
(6) Peng J, Yang Y, Feng X, Cheng G*, Lin J*. Molecular characterizations of an inhibitor of apoptosis from Schistosoma japonicum. Parasitol Res. 2010;106(4):967-76. (2010 SCI IF=1.812)
(7) Cheng G, Fu Z, Lin J, Shi Y, Zhou Y, Jin Y, Cai Y. In vitro and in vivo evaluation of small interference RNA-mediated gynaecophoral canal protein silencing in Schistosoma japonicum. J Gene Med. 2009;11(5):412-21. (2009 SCI IF=2.986)
(8) Cheng G, Zhu L, Mahato RI. Caspase-3 gene silencing for inhibiting apoptosis in insulinoma cells and human islets. Mol Pharm. 2008;5(6):1093-102. (2008 SCI IF=4.565)
(9) Chen Y, Cheng G, Mahato RI. RNAi for treating hepatitis B viral infection. Pharm Res. 2008;25(1):72-86. (2008 SCI IF=4.024)
(10) Cheng G, Davis RE. An improved and secreted luciferase reporter for schistosomes. Mol Biochem Parasitol. 2007;155(2):167-71. (2007 SCI IF=2.896) 【Selected by Faculty 1000 biology】
(11) Cheng G, Cohen L, Mikhli C, Jankowska-Anyszka M, Stepinski J, Darzynkiewicz E, Davis RE. In vivo translation and stability of trans-spliced mRNAs in nematode embryos. Mol Biochem Parasitol. 2007;153(2):95-106. (2007 SCI IF=2.896)
(12) Cheng G, Cohen L, Ndegwa D, Davis RE. The flatworm spliced leader 3'-terminal AUG as a translation initiator methionine. J Biol Chem. 2006 13;281(2):733-43. (2006 SCI IF=5.808)
(13) Cheng GF, Lin JJ, Shi Y, Jin YX, Fu ZQ, Jin YM, Zhou YC, Cai YM. Dose-dependent inhibition of gynecophoral canal protein gene expression in vitro in the schistosome (Schistosoma japonicum) by RNA interference. Acta Biochim Biophys Sin. 2005;37(6):386-90. (2005 SCI IF=0.505)
(14) Cheng GF, Lin JJ, Feng XG, Fu ZQ, Jin YM, Yuan CX, Zhou YC, Cai YM. Proteomic analysis of differentially expressed proteins between the male and female worm of Schistosoma japonicum after pairing. Proteomics. 2005;5(2):511-21. (2005 SCI IF=6.08)
(15) 張亮, 程國鋒, 付志強, 金亞美, 馮新港, 苑純秀, 蔡幼民. 血吸蟲新抗原基因SjMF4的克隆、表達及功能分析. 生物化學與生物物理學報, 2003,35(12):1099-1104. (2003 SCI IF=0.524)
B． 編著
(16) Cheng G, Danquah M and Mahato RI (2009) MicroRNAs as therapeutic targets for cancer. In: Lu Y and Mahato RI (eds) Pharmaceutical Perspectives of Cancer Therapeutics (ISBN: 978-1-4419-0130-9) Springer, New York, NY. pp441-474.
科研經歷
2001.2-2005.1 中國農業科學院上海家畜寄生蟲病研究所，博士研究生；
2005.4-2007.4 University of Colorado School of Medicine，博士後；
2007.4-2008.8 The University of Tennessee Health Science Center，研究助理；
2008.8-至今 中國農業科學院上海獸醫研究所，研究員，課題組長。
獲獎記錄
2006年獲上海明治生命科學獎科學獎；
2007年獲全國百篇優秀博士論文提名；
2008年獲中國農業科學院科學技術成果獎二等獎（第三完成人）；
2008年獲上海市科技進步獎二等獎（第三完成人）；
2009年獲上海市領軍人才後備隊培養計畫（閔行領軍人才）；
2009年獲上海市人才發展資金資助；
2010年獲上海市浦江人才稱號並獲資助。
